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Melanie A. Wellington, M.D., Ph.D.



Showing all 23 journal articles & 4 books available

Journal Articles

Chang YL, Yu SJ, Heitman J, Wellington M, Chen YL. "New facets of antifungal therapy." Virulence.. 2017 Feb 17; 8(2):222-236. Epub 2016 Nov 07.

Koselny K, Green J, DiDone L, Halterman JP, Fothergill AW, Wiederhold NP, Patterson TF, Cushion MT, Rappelye C, Wellington M, Krysan DJ. "The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis." Antimicrobial agents and chemotherapy.. 2016 Dec 0; 60(12):7115-7127. Epub 2016 Nov 21.

Krysan DJ, Sutterwala FS, Wellington M. "Catching fire: Candida albicans, macrophages, and pyroptosis." PLoS pathogens.. 2014 Jun 0; 10(6):e1004139. Epub 2014 Jun 26.

Harrison BD, Hashemi J, Bibi M, Pulver R, Bavli D, Nahmias Y, Wellington M, Sapiro G, Berman J. "A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole." PLoS biology.. 2014 Mar 0; 12(3):e1001815. Epub 2014 Mar 18.

Butts A, Koselny K, Chabrier-Roselló Y, Semighini CP, Brown JC, Wang X, Annadurai S, Didone L, Tabroff J, Childers WE, Abou-Gharbia M, Wellington M, Cardenas ME, Madhani HD, Heitman J, Krysan DJ. "Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo." mBio. 2014 Feb 11; 5(1):e00765-13. Epub 2014 Feb 11.

Wellington M, Koselny K, Sutterwala FS, Krysan DJ. "Candida albicans triggers NLRP3-mediated pyroptosis in macrophages." Eukaryotic cell.. 2014 Feb 0; 13(2):329-40. Epub 2013 Dec 27.

Butts A, Didone L, Koselny K, Baxter BK, Chabrier-Rosello Y, Wellington M, Krysan DJ. "A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis." Eukaryotic cell.. 2013 Feb 0; 12(2):278-87. Epub 2012 Dec 14.

Wellington M, Koselny K, Krysan DJ. "Candida albicans morphogenesis is not required for macrophage interleukin 1? production." mBio. 2012 Dec 26; 4(1):e00433-12. Epub 2012 Dec 26.

Kajfasz JK, Mendoza JE, Gaca AO, Miller JH, Koselny KA, Giambiagi-Demarval M, Wellington M, Abranches J, Lemos JA. "The Spx regulator modulates stress responses and virulence in Enterococcus faecalis." Infection and immunity.. 2012 Jul 0; 80(7):2265-75. Epub 2012 Apr 16.

Mitra S, Dolan K, Foster TH, Wellington M. "Imaging morphogenesis of Candida albicans during infection in a live animal." Journal of biomedical optics.. 2010 15(1):010504.

Van Alst NE, Wellington M, Clark VL, Haidaris CG, Iglewski BH. "Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa." Infection and immunity.. 2009 Oct 0; 77(10):4446-54. Epub 2009 Aug 03.

Dolan K, Montgomery S, Bucchiet B, Didone L, Wellington M, Krysan DJ. "Antifungal activity of tamoxifen: in vitro and in vivo activities and mechanistic characterization." Antimicrobial agents and chemotherapy.. 2009 Aug 0; 53(8):3337-46. Epub 2009 Jun 01.

Wellington M, Dolan K, Krysan DJ. "Live Candida albicans suppresses production of reactive oxygen species in phagocytes." Infection and immunity.. 2009 Jan 0; 77(1):405-13. Epub 2008 Nov 03.

Oberholzer CM, Wellington M. "Serologic diagnosis of infectious diseases in the adolescent." Adolescent Medicine: State of the Art Reviews. 2008; 19: 135-48.

Wellington M, Dolan K, Haidaris CG. "Monocyte responses to Candida albicans are enhanced by antibody in cooperation with antibody-independent pathogen recognition." FEMS immunology and medical microbiology.. 2007 Oct 0; 51(1):70-83. Epub 2007 Jul 04.

Wellington M, Kabir MA, Rustchenko E. "5-fluoro-orotic acid induces chromosome alterations in genetically manipulated strains of Candida albicans." Mycologia.. 2006 98(3):393-8.

Wellington MA, Bonnez W. "Consultation with the specialist: genital warts." Pediatrics in review. 2005 Dec 0; 26(12):467-71.

Wellington M, Rustchenko E. "5-Fluoro-orotic acid induces chromosome alterations in Candida albicans." Yeast (Chichester, England). 2005 Jan 15; 22(1):57-70.

Wang YK, Das B, Huber DH, Wellington M, Kabir MA, Sherman F, Rustchenko E. "Role of the 14-3-3 protein in carbon metabolism of the pathogenic yeast Candida albicans." Yeast (Chichester, England). 2004 Jun 0; 21(8):685-702.

Wellington M, Bliss JM, Haidaris CG. "Enhanced phagocytosis of Candida species mediated by opsonization with a recombinant human antibody single-chain variable fragment." Infection and immunity.. 2003 Dec 0; 71(12):7228-31.

Bliss JM, Wellington M, Gigliotti F. "Antifungal pharmacotherapy for neonatal candidiasis." Seminars in perinatology.. 2003 Oct 0; 27(5):365-74.

Wellington M, Hall CB. "Pacifier as a risk factor for acute otitis media." Pediatrics.. 2002 Feb 0; 109(2):351-2; author reply 353.

Wellington M, Gigliotti F. "Update on antifungal agents." The Pediatric infectious disease journal.. 2001 Oct 0; 20(10):993-5.

Books & Chapters

Chapter Title: Feigin and Cherry's Textbook of Pediatric Infectious Diseases
Book Title: Feigin and Cherry's Textbook of Pediatric Infectious Diseases
Author List: Krysan DJ, Wellington M, Steinbach WJ
Edited By: Cherry J, Harrison GJ, Kaplan S, Peter J, Hotez PJ, Steinbach, WJ
Published By: Saunders Elsevier2014 in Philadelphia

Chapter Title: Typhoid fever and Salmonella infections
Book Title: Pediatric Clinical Advisor
Author List: Wellington M
Edited By: Garfunkel LC, Kaczorowski J, Christy C
Published By: Mosby, Inc.2007 in St. Louis, MO

Chapter Title: Discitis
Book Title: Pediatric Clinical Advisor
Author List: Wellington M
Edited By: Garfunkel LC, Kaczorowski J, Christy C
Published By: Mosby, Inc.2007 in St. Louis, MO

Chapter Title: Typhoid fever and Salmonella infections.
Book Title: Pediatric Clinical Advisor
Author List: Wellington, M.
Edited By: Garfunkel, L.C.; Kaczorowski, J.; Christy, C.
Published By: Mosby, Inc.2002 in St. Louis