Lin Gan, Ph.D.

Lin Gan, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 659
Rochester, NY 14642

Office: (585) 273-1510
Lab: (585) 273-1513
Fax: (585) 276-2432

Journal Articles

Showing all 94 journal articles available.

2016 Jun 27
Ding Q, Balasubramanian R, Zheng D, Liang G, Gan L. "Barhl2 Determines the Early Patterning of the Diencephalon by Regulating Shh." Molecular neurobiology. 2016 Jun 27; Epub 2016 Jun 27.
2016 May
Yao Y, Minor PJ, Zhao YT, Jeong Y, Pani AM, King AN, Symmons O, Gan L, Cardoso WV, Spitz F, Lowe CJ, Epstein DJ. "Cis-regulatory architecture of a brain signaling center predates the origin of chordates." Nature genetics. 2016 May; 48(5):575-80. Epub 2016 Apr 11.
2016 Apr 20
Xu J, Wu XS, Sheng J, Zhang Z, Yue HY, Sun L, Sgobio C, Lin X, Peng S, Jin Y, Gan L, Cai H, Wu LG. "?-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 Apr 20; 36(16):4408-14.
2016 Mar 25
Huang H, Yang X, Bao M, Cao H, Miao X, Zhang X, Gan L, Qiu M, Zhang Z. "Ablation of the Sox11 Gene Results in Clefting of the Secondary Palate Resembling the Pierre Robin Sequence." The Journal of biological chemistry. 2016 Mar 25; 291(13):7107-18. Epub 2016 Jan 29.
Li, L., Cao, Y., Wu, H., Ye, X., Zhu, Z., Xing, G., Shen, C., Barik, A., Zhang, B., Xie, X., Zhi, W., Gan, L., Su, H., Xiong, WC., and Mei, L. "Enzymatic Activity of the Scaffold Protein Rapsyn for Synapse Formation." Neuron. 2016; . Link
Maruyama EO, Aure MH, Xie X, Myal Y, Gan L, Ovitt CE. "Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands." PloS one. 2016 11(1):e0146711. Epub 2016 Jan 11.
2015 Nov
Luo XJ, Mattheisen M, Li M, Huang L, Rietschel M, Børglum AD, Als TD, van den Oord EJ, Aberg KA, Mors O, Mortensen PB, Luo Z, Degenhardt F, Cichon S, Schulze TG, Nöthen MM, , , Su B, Zhao Z, Gan L, Yao YG. "Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function." Schizophrenia bulletin. 2015 Nov; 41(6):1294-308. Epub 2015 Mar 10.
2015 Oct
Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA. "ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism." Molecular endocrinology. 2015 Oct; 29(10):1510-21. Epub 2015 Aug 21.
2015 May
Luo XJ, Huang L, Oord EJ, Aberg KA, Gan L, Zhao Z, Yao YG. "Common variants in the MKL1 gene confer risk of schizophrenia." Schizophrenia bulletin. 2015 May; 41(3):715-27. Epub 2014 Nov 07.
2015 Mar 15
Eblimit A, Nguyen TM, Chen Y, Esteve-Rudd J, Zhong H, Letteboer S, van Reeuwijk J, Simons DL, Ding Q, Wu KM, Li Y, van Beersum S, Moayedi Y, Xu H, Pickard P, Wang K, Gan L, Wu SM, Williams DS, Mardon G, Roepman R, Chen R. "Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina." Human molecular genetics. 2015 Mar 15; 24(6):1584-601. Epub 2014 Nov 14.
Guo X, Ruan H, Li X, Qin L, Tao Y, Qi X, Gao J, Gan L, Duan S, Shen W. "Subcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum." Frontiers in cellular neuroscience. 2015 9:510. Epub 2016 Jan 12.
2014 Nov
Luo X, Huang L, Han L, Luo Z, Hu F, Tieu R, Gan L. "Systematic prioritization and integrative analysis of copy number variations in schizophrenia reveal key schizophrenia susceptibility genes." Schizophrenia bulletin. 2014 Nov; 40(6):1285-99. Epub 2014 Mar 24.
2014 Sep 1
Balasubramanian R, Gan L. "Development of Retinal Amacrine Cells and Their Dendritic Stratification." Current ophthalmology reports. 2014 Sep 1; 2(3):100-106.
2014 Sep
Balasubramanian R, Bui A, Xie X, Deng M, Gan L. "Generation and characterization of Lhx9-GFPCreER(T2) knock-in mouse line." Genesis : the journal of genetics and development. 2014 Sep; 52(9):827-32. Epub 2014 Aug 12.
2014 May
Deng M, Yang H, Xie X, Liang G, Gan L. "Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons." Gene expression patterns : GEP. 2014 May; 15(1):31-7. Epub 2014 Apr 04.
2014 Apr
Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Arias Vasquez A, Hibar DP, Franke B, Martin NG, Wright MJ, , Strohmaier J, Breuer R, Meier S, Mühleisen TW, Degenhardt FA, Hoffmann P, Herms S, Schwarz M, Vedder H, Kammerer-Ciernioch J, Reif A, Sasse J, Bauer M, Zwick S, Hautzinger M, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Martin NG, Czerski PM, Hauser J, Schumacher J, Maier W, Propping P, , Backlund L, Frisén L, Lavebratt C, Schalling M, Osby U, , , , Su B. "Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility." Molecular psychiatry. 2014 Apr; 19(4):452-61. Epub 2013 Apr 09.
2014 Feb
Huang L, Hu F, Feng L, Luo XJ, Liang G, Zeng XY, Yi JL, Gan L. "Bhlhb5 is required for the subtype development of retinal amacrine and bipolar cells in mice." Developmental dynamics : an official publication of the American Association of Anatomists. 2014 Feb; 243(2):279-89. Epub 2013 Nov 13.
2014 Feb
Xiao H, Dairaghi DJ, Powers JP, Ertl LS, Baumgart T, Wang Y, Seitz LC, Penfold ME, Gao L, Hu P, Lu B, Gerard NP, Gerard C, Schall TJ, Jaen JC, Falk RJ, Jennette JC. "C5a receptor (CD88) blockade protects against MPO-ANCA GN." Journal of the American Society of Nephrology : JASN. 2014 Feb; 25(2):225-31. Epub 2013 Oct 31.
2014 Jan
Luo X, Huang L, Jia P, Li M, Su B, Zhao Z, Gan L. "Protein-protein interaction and pathway analyses of top schizophrenia genes reveal schizophrenia susceptibility genes converge on common molecular networks and enrichment of nucleosome (chromatin) assembly genes in schizophrenia susceptibility loci." Schizophrenia bulletin. 2014 Jan; 40(1):39-49. Epub 2013 May 12.
2014 Jan
Balasubramanian R, Bui A, Ding Q, Gan L. "Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina." Gene expression patterns : GEP. 2014 Jan; 14(1):1-8. Epub 2013 Dec 10.
Deng M; Luo XJ; Pan L; Yang H; Xie X; Liang G; Huang L; Hu F; Kiernan AE; Gan L. "LMO4 Functions As a Negative Regulator of Sensory Organ Formation in the Mammalian Cochlea." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014; 34(30): 10072-7. (Selected for F1000Prime).
Luo XJ; Li M; Huang L; Steinberg S; Mattheisen M; Liang G; Donohoe G; Shi Y; Chen C; Yue W; Alkelai A; Lerer B; Li Z; Yi Q; Rietschel M; Cichon S; Collier DA; Tosato S; Suvisaari J; Rujescu D; Golimbet V; Silagadze T; Durmishi N; Milovancevic MP; Stefansson H; Schulze TG; Nöthen MM; Chen C; Lyne R; Morris DW; Gill M; Corvin A; Zhang D; Dong Q; Moyzis RK; Stefansson K; Sigurdsson E; Hu F; ; Su B; Gan L. "Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene". Molecular Psychiatry. 2014; 19(7): 774-83. (Selected for F1000Prime).
Huang L, Hu F, Xie X, Harder J, Fernandes K, Zeng XY, Libby R, Gan L. "Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice." PloS one. 2014 9(4):e94173. Epub 2014 Apr 15.
Savoy-Burke G, Gilels FA, Pan W, Pratt D, Que J, Gan L, White PM, Kiernan AE. "Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells." PloS one. 2014 9(9):e108160. Epub 2014 Sep 29.
Hu F, Zeng XY, Liu LL, Luo YL, Jiang YP, Wang H, Xie J, Hu CQ, Gan L, Huang L. "Genetic analysis of Chinese families reveals a novel truncation allele of the retinitis pigmentosa GTPase regulator gene." International journal of ophthalmology. 2014 7(5):753-8. Epub 2014 Oct 18.
2013 Dec 4
Au E, Ahmed T, Karayannis T, Biswas S, Gan L, Fishell G. "A modular gain-of-function approach to generate cortical interneuron subtypes from ES cells." Neuron. 2013 Dec 4; 80(5):1145-58.
2013 Nov
Huang L, Hu F, Zeng X, Gan L, Luo XJ. "Further evidence for the association between the LSM1 gene and schizophrenia." Schizophrenia research. 2013 Nov; 150(2-3):588-9. Epub 2013 Sep 11.
2013 Jun 21
Jiang Y, Ding Q, Xie X, Libby R, Lefebvre V, Gan L. "Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells." The Journal of biological chemistry. 2013 Jun 21; 288(25):18429-38. Epub 2013 May 06.
2013 Feb
Luo XJ, Huang L, Li M, Gan L. "Protein-protein interaction analysis reveals common molecular processes/pathways that contribute to risk of schizophrenia." Schizophrenia research. 2013 Feb; 143(2-3):390-2. Epub 2012 Dec 29.
Luo XJ; Deng M; Xie X; Huang L; Wang H; Jiang L; Liang G; Hu F; Tieu R; Chen R; Gan L. "GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea." Human molecular genetics. 2013; 22: 3609-3623. (Cover Photograph).
2012 Dec
Chatterjee M, Li K, Chen L, Maisano X, Guo Q, Gan L, Li JY. "Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes." Development. 2012 Dec; 139(24):4633-43. Epub 2012 Nov 07.
2012 Aug
Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT. "BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells." Molecular and cellular neurosciences. 2012 Aug; 51(1-2):53-9. Epub 2012 Jul 24.
2012 Jul 12
Wu H, Lu Y, Shen C, Patel N, Gan L, Xiong WC, Mei L. "Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation." Neuron. 2012 Jul 12; 75(1):94-107.
2012 May 9
Liu Z, Dearman JA, Cox BC, Walters BJ, Zhang L, Ayrault O, Zindy F, Gan L, Roussel MF, Zuo J. "Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 May 9; 32(19):6600-10.
2012 Jan 31
Ding Q, Joshi PS, Xie ZH, Xiang M, Gan L. "BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord." Proceedings of the National Academy of Sciences of the United States of America. 2012 Jan 31; 109(5):1566-71. Epub 2012 Jan 17.
Bjerknes M; Khandanpour C; Möröy T; Fujiyama T; Hoshino M; Klisch TJ; Ding Q; Gan L; Wang J; Martín MG; Cheng H. "Origin of the brush cell lineage in the mouse intestinal epithelium". Developmental biology. 2012; Epub 2011 Dec 13.(362): 194–218. (Cover Photograph).
Ding Q, Gan L. "Conditional control of gene expression in the mouse retina." Methods in molecular biology. 2012 884:3-15.
Luo XJ, Li M, Huang L, Nho K, Deng M, Chen Q, Weinberger DR, Vasquez AA, Rijpkema M, Mattay VS, Saykin AJ, Shen L, Fernández G, Franke B, Chen JC, Chen XN, Wang JK, Xiao X, Qi XB, Xiang K, Peng YM, Cao XY, Li Y, Shi XD, , Gan L, Su B. "The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors." PloS one. 2012 7(11):e50375. Epub 2012 Nov 30.
2011 Jun 7
Whitney IE, Raven MA, Ciobanu DC, Poché RA, Ding Q, Elshatory Y, Gan L, Williams RW, Reese BE. "Genetic modulation of horizontal cell number in the mouse retina." Proceedings of the National Academy of Sciences of the United States of America. 2011 Jun 7; 108(23):9697-702. Epub 2011 May 16.
Feng L; Eisenstat DD; Chiba S; Ishizaki Y; Gan L; Shibasaki K. "Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina". Neuroscience. 2011; 195: 9-20. (Cover Photograph).
2010 Nov 18
Feng L, Xie ZH, Ding Q, Xie X, Libby RT, Gan L. "MATH5 controls the acquisition of multiple retinal cell fates." Molecular brain. 2010 Nov 18; 3:36. Epub 2010 Nov 18.
2010 Nov 1
Berahovich RD, Zabel BA, Penfold ME, Lewén S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ. "CXCR7 protein is not expressed on human or mouse leukocytes." The Journal of immunology : official journal of the American Association of Immunologists. 2010 Nov 1; 185(9):5130-9. Epub 2010 Oct 01.
2010 Jun
Yang H, Gan J, Xie X, Deng M, Feng L, Chen X, Gao Z, Gan L. "Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion." Genesis : the journal of genetics and development. 2010 Jun; 48(6):400-6.
2010 Feb 25
Xu HP, Chen H, Ding Q, Xie ZH, Chen L, Diao L, Wang P, Gan L, Crair MC, Tian N. "The immune protein CD3zeta is required for normal development of neural circuits in the retina." Neuron. 2010 Feb 25; 65(4):503-15.
2010 Feb
Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK. "Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice." Developmental dynamics : an official publication of the American Association of Anatomists. 2010 Feb; 239(2):505-13.
Deng M; Pan L; Xie X; Gan L. "Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear". Developmental Biology. 2010; 338: 38–49 (Cover Photograph).
Yang, H., Xie, X., Deng, M., Chen, X., and Gan, L. "Generation and characterization of Atoh1-Cre knock-in mouse line". Genesis: The Journal of Genetics and Development. 2010; 48: 407–413. (Cover Photograph).
2009 May 27
Sakagami K, Gan L, Yang XJ. "Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009 May 27; 29(21):6932-44.
Ding, Q., Chen, H., Xie, X., Libby, R., Tian, N., and Gan, L. "BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons." Journal of Neuroscience. 2009; 29(13): 3992– 4003 (Cover Photograph).
2008 Oct 23
Joshi PS, Molyneaux BJ, Feng L, Xie X, Macklis JD, Gan L. "Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex." Neuron. 2008 Oct 23; 60(2):258-72.
2008 Mar 26
Elshatory Y, Gan L. "The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Mar 26; 28(13):3291-7.
Pan L; Deng M; Xie X; Gan L. "ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells". Development (Cambridge, England). 2008; 135(11): 1981-90 (Cover Photograph).
2007 Nov 14
Elshatory Y, Everhart D, Deng M, Xie X, Barlow RB, Gan L. "Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cells." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007 Nov 14; 27(46):12707-20.
2007 Jul 1
Elshatory Y, Deng M, Xie X, Gan L. "Expression of the LIM-homeodomain protein Isl1 in the developing and mature mouse retina." The Journal of comparative neurology. 2007 Jul 1; 503(1):182-97.
2007 Jan
Shibasaki K, Takebayashi H, Ikenaka K, Feng L, Gan L. "Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells." Gene expression patterns : GEP. 2007 Jan; 7(1-2):57-65. Epub 2006 May 26.
2006 Oct
Deng M, Pan L, Xie X, Gan L. "Differential expression of LIM domain-only (LMO) genes in the developing mouse inner ear." Gene expression patterns : GEP. 2006 Oct; 6(8):857-63. Epub 2006 Apr 04.
Feng L; Xie X; Joshi PS; Yang Z; Shibasaki K; Chow RL; Gan L. "Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina". Development (Cambridge, England). 2006; 133(24): 4815-25. Epub 2006 Nov 08. (Cover Photograph).
2005 Jul 20
Xie J, Lü L, Deng M, Weng S, Zhu J, Wu Y, Gan L, Chan SM, He J. "Inhibition of reporter gene and Iridovirus-tiger frog virus in fish cell by RNA interference." Virology. 2005 Jul 20; 338(1):43-52.
Pan L; Yang Z; Feng L; Gan L. "Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis". Development (Cambridge, England). 2005; 132(4): 703-12. Epub 2005 Jan 12. (Cover Photograph).
2004 Sep 27
Radde-Gallwitz K, Pan L, Gan L, Lin X, Segil N, Chen P. "Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear." The Journal of comparative neurology. 2004 Sep 27; 477(4):412-21.
2004 Mar 11
Yan DH, Wen Y, Su LK, Xia W, Wang SC, Zhang S, Gan L, Lee DF, Spohn B, Frey JA, Hortobagyi GN, Hung MC. "A delayed chemically induced tumorigenesis in Brca2 mutant mice." Oncogene. 2004 Mar 11; 23(10):1896-901.
2003 Dec 1
Yang Z, Ding K, Pan L, Deng M, Gan L. "Math5 determines the competence state of retinal ganglion cell progenitors." Developmental biology. 2003 Dec 1; 264(1):240-54.
2002 Dec 20
Lu JR, Bassel-Duby R, Hawkins A, Chang P, Valdez R, Wu H, Gan L, Shelton JM, Richardson JA, Olson EN. "Control of facial muscle development by MyoR and capsulin." Science. 2002 Dec 20; 298(5602):2378-81.
2002 Dec 1
Wee R, Castrucci AM, Provencio I, Gan L, Van Gelder RN. "Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Dec 1; 22(23):10427-33.
2002 Oct 15
Yeh S, Tsai MY, Xu Q, Mu XM, Lardy H, Huang KE, Lin H, Yeh SD, Altuwaijri S, Zhou X, Xing L, Boyce BF, Hung MC, Zhang S, Gan L, Chang C, Hung MC. "Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues." Proceedings of the National Academy of Sciences of the United States of America. 2002 Oct 15; 99(21):13498-503. Epub 2002 Oct 07.
2002 Aug
Guo Z, Clydesdale G, Cheng J, Kim K, Gan L, McConkey DJ, Ullrich SE, Zhuang Y, Su B. "Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction." Molecular and cellular biology. 2002 Aug; 22(16):5761-8.
2002 Jan
Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH. "Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth." Development. 2002 Jan; 129(2):467-77.
2001 Dec 15
Mu X, Zhao S, Pershad R, Hsieh TF, Scarpa A, Wang SW, White RA, Beremand PD, Thomas TL, Gan L, Klein WH. "Gene expression in the developing mouse retina by EST sequencing and microarray analysis." Nucleic acids research. 2001 Dec 15; 29(24):4983-93.
2001 Nov
Kim BS, Savinova OV, Reedy MV, Martin J, Lun Y, Gan L, Smith RS, Tomarev SI, John SW, Johnson RL. "Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function." Molecular and cellular biology. 2001 Nov; 21(22):7707-13.
2001 Jan 15
Eng SR, Gratwick K, Rhee JM, Fedtsova N, Gan L, Turner EE. "Defects in sensory axon growth precede neuronal death in Brn3a-deficient mice." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2001 Jan 15; 21(2):541-9.
2001 Jan 1
Wang SW, Kim BS, Ding K, Wang H, Sun D, Johnson RL, Klein WH, Gan L. "Requirement for math5 in the development of retinal ganglion cells." Genes & development. 2001 Jan 1; 15(1):24-9.
2000 Aug 15
Lu J, Chang P, Richardson JA, Gan L, Weiler H, Olson EN. "The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis." Proceedings of the National Academy of Sciences of the United States of America. 2000 Aug 15; 97(17):9525-30.
Wang SW; Gan L; Martin SE; Klein WH. "Abnormal polarization and axon outgrowth in retinal ganglion cells lacking the POU-domain transcription factor Brn-3b". Molecular and Cellular Neurosciences. 2000; 16(2): 141-56. (Cover Photograph).
1999 Sep 7
Wagner DS, Gan L, Klein WH. "Identification of a differentially expressed RNA helicase by gene trapping." Biochemical and biophysical research communications. 1999 Sep 7; 262(3):677-84.
1999 Jun 15
Gan L, Wang SW, Huang Z, Klein WH. "POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification." Developmental biology. 1999 Jun 15; 210(2):469-80.
1999 Apr 1
Vivian JL, Gan L, Olson EN, Klein WH. "A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation." Developmental biology. 1999 Apr 1; 208(1):44-55.
1998 Sep 29
Wagner DS, Gan L, Klein WH. "Expression of a gene trap reporter construct in a subset of cells in embryonic sites of hematopoiesis: evidence for alternative rRNA production in hematopoietic cells." Biochemical and biophysical research communications. 1998 Sep 29; 250(3):674-81.
1998 Jul 30
Lin X, Gan L, Klein WH, Wells D. "Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene." Biochemical and biophysical research communications. 1998 Jul 30; 248(3):738-43.
1998 Jul 23
Evrard YA, Lun Y, Aulehla A, Gan L, Johnson RL. "lunatic fringe is an essential mediator of somite segmentation and patterning." Nature. 1998 Jul 23; 394(6691):377-81.
1998 May
Chen H, Lun Y, Ovchinnikov D, Kokubo H, Oberg KC, Pepicelli CV, Gan L, Lee B, Johnson RL. "Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome." Nature genetics. 1998 May; 19(1):51-5.
1997 Aug 19
Xiang M, Gan L, Li D, Chen ZY, Zhou L, O'Malley BW, Klein W, Nathans J. "Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development." Proceedings of the National Academy of Sciences of the United States of America. 1997 Aug 19; 94(17):9445-50.
Klein, W.H., Mao, C-A., Gan, L., Chuang, C-K., and Wikramanayake, A.H. "Manipulating cell fates in the sea urchin embryo". Invertebrate Reproduction and Development. 1997; 31(1-3): 21-29.
Xiang M, Gan L, Li D, Zhou L, Chen ZY, Wagner D, O'Malley BW, Klein W, Nathans J. "Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems." Cold Spring Harbor symposia on quantitative biology. 1997 62:325-36.
1996 Oct 15
Xiang M, Gan L, Zhou L, Klein WH, Nathans J. "Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling." Proceedings of the National Academy of Sciences of the United States of America. 1996 Oct 15; 93(21):11950-5.
1996 May
Mao CA, Wikramanayake AH, Gan L, Chuang CK, Summers RG, Klein WH. "Altering cell fates in sea urchin embryos by overexpressing SpOtx, an orthodenticle-related protein." Development. 1996 May; 122(5):1489-98.
1996 Apr 30
Gan L, Xiang M, Zhou L, Wagner DS, Klein WH, Nathans J. "POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells." Proceedings of the National Academy of Sciences of the United States of America. 1996 Apr 30; 93(9):3920-5.
1995 Feb
Gan L, Mao CA, Wikramanayake A, Angerer LM, Angerer RC, Klein WH. "An orthodenticle-related protein from Strongylocentrotus purpuratus." Developmental biology. 1995 Feb; 167(2):517-28.
1994 Sep
Mao CA, Gan L, Klein WH. "Multiple Otx binding sites required for expression of the Strongylocentrotus purpuratus Spec2a gene." Developmental biology. 1994 Sep; 165(1):229-42.
1993 May
Gan L, Klein WH. "A positive cis-regulatory element with a bicoid target site lies within the sea urchin Spec2a enhancer." Developmental biology. 1993 May; 157(1):119-32.
1993 Apr
Venuti JM, Gan L, Kozlowski MT, Klein WH. "Developmental potential of muscle cell progenitors and the myogenic factor SUM-1 in the sea urchin embryo." Mechanisms of development. 1993 Apr; 41(1):3-14.
1991 Dec
Kozlowski MT, Gan L, Venuti JM, Sawadogo M, Klein WH. "Sea urchin USF: a helix-loop-helix protein active in embryonic ectoderm cells." Developmental biology. 1991 Dec; 148(2):625-30.
1990 Dec
Gan L, Wessel GM, Klein WH. "Regulatory elements from the related spec genes of Strongylocentrotus purpuratus yield different spatial patterns with a lacZ reporter gene." Developmental biology. 1990 Dec; 142(2):346-59.
Klein, W.H., Tomlinson, C.R., Zhang, W., Xiang, M., Kozlowski, M.T., Gan, L., Nguyen, T., and Wessel, G.M. "Ectoderm differentiation and the Spec gene family of sea urchin. In Developmental biology". UCLA Symposium on Molecular and Cellular Biology, New Series. 1990; 125: 123-134.
Gan L; Zhang W; Klein WH. "Repetitive DNA sequences linked to the sea urchin spec genes contain transcriptional enhancer-like elements". Developmental Biology. 1990; 139(1): 186-96. (Cover Photograph).