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Irena Nowak, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 647
Rochester, NY 14642

Journal Articles

Showing all 21 journal articles available.

Sun H; Tsai Y; Nowak I; Liesveld J; Chen Y. "Eltrombopag, a thrombopoietin receptor agonist, enhances human umbilical cord blood hematopoietic stem/primitive progenitor cell expansion and promotes multi-lineage hematopoiesis". Stem Cell Research. 2012; .
2011 Jan 10
Sun H, Tsai Y, Nowak I, Dertinger SD, Wu JH, Chen Y. "Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture." Mutation research. 2011 Jan 10; 718(1-2):38-43. Epub 2010 Nov 04.
2010 Feb
Chen Y, Tsai Y, Nowak I, Wang N, Hyrien O, Wilkins R, Ferrarotto C, Sun H, Dertinger SD. "Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model." Health physics. 2010 Feb; 98(2):218-27.
2009 Apr 30
Dertinger SD, Bemis JC, Phonethepswath S, Tsai Y, Nowak I, Hyrien O, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: effect of age." Mutation research. 2009 Apr 30; 675(1-2):77-80. Epub 2009 Feb 11.
2007 Dec 1
Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry." Mutation research. 2007 Dec 1; 634(1-2):119-25. Epub 2007 Jul 05.
2003 Apr 18
Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA. "Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes." The Journal of biological chemistry. 2003 Apr 18; 278(16):13740-6. Epub 2003 Jan 30.
2002 Dec
Senn JJ, Klover PJ, Nowak IA, Mooney RA. "Interleukin-6 induces cellular insulin resistance in hepatocytes." Diabetes. 2002 Dec; 51(12):3391-9.
1998 Jul
Shaw LM, Korecka M, van Breeman R, Nowak I, Brayman KL. "Analysis, pharmacokinetics and therapeutic drug monitoring of mycophenolic acid." Clinical biochemistry. 1998 Jul; 31(5):323-8.
1998 Mar
Shaw LM, Mick R, Nowak I, Korecka M, Brayman KL. "Pharmacokinetics of mycophenolic acid in renal transplant patients with delayed graft function." Journal of clinical pharmacology. 1998 Mar; 38(3):268-75.
1998 Feb
Wasik MA, Nowak I, Zhang Q, Shaw LM. "Suppression of proliferation and phosphorylation of Jak3 and STAT5 in malignant T-cell lymphoma cells by derivatives of octylamino-undecyl-dimethylxanthine." Leukemia & lymphoma. 1998 Feb; 28(5-6):551-60.
1997 Jun
Nowak I, Shaw LM. "Effect of mycophenolic acid glucuronide on inosine monophosphate dehydrogenase activity." Therapeutic drug monitoring. 1997 Jun; 19(3):358-60.
Nowak I, Wu J, Brayman KL, Shaw LM. "Is the glucuronide metabolite of MPA pharmacologically active?" Transplantation proceedings. 1997 29(1-2):337.
1996 Aug 20
Zhang Q, Nowak I, Vonderheid EC, Rook AH, Kadin ME, Nowell PC, Shaw LM, Wasik MA. "Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome." Proceedings of the National Academy of Sciences of the United States of America. 1996 Aug 20; 93(17):9148-53.
1995 Dec
Shaw LM, Nowak I. "Mycophenolic acid: measurement and relationship to pharmacologic effects." Therapeutic drug monitoring. 1995 Dec; 17(6):685-9.
1995 Jul
Nowak I, Shaw LM. "Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics." Clinical chemistry. 1995 Jul; 41(7):1011-7.
Twardowski J; Nowak I. "Structure and function of enzymes". Zagadnienia Biofizyki Wspolczesnej. 1989; : 83-102.
Nowak I; Anzenbacher P; Twardowski J. "Application of Resonance Raman effect to structure and dynamics studies of enzymes". Zagadnienia Biofizyki Wspolczesnej. 1988; 13: 31-50.
Twardowski J; Nowak I. "Post-translational modification of lysosomal hydrolases". Zagadnienia Biofizyki Wspolczesnej. 1988; : 61-80.
Twardowski J, Wójczyk B, Nowak I. "An isoelectric focusing study of acid phosphatase heterogeneity in rat liver." Acta physiologica Hungarica. 1987 69(1):85-94.
Nowak I, Urbanik-Brzóska A, Twardowski J, Anzenbacher P. "The rhythm of acid phosphatase activity in adult and old rat livers." Folia biologica. 1985 33(3-4):159-65.
1984 Oct 9
Twardowski J, Nowak I, Stufkens DJ, Snoeck TL. "Raman and infrared studies of homogeneous forms of acid phosphatase from rat liver." Biochimica et biophysica acta. 1984 Oct 9; 790(1):70-7.


Twardowski J; Nowak I. "Orthophosphoric monoester phosphohydrolase heterogeneity in rat liver postlysosomal supernatant". Spectroscopic and structural studies of biomaterials. Twardowski J. Wilmslow, Cheshire, UK: Sigma Press, 1988. 257-265
Twardowski J; Nowak I. "Study of acid phosphatase by Raman spectroscopy". Laser Scattering Spectroscopy of Biological Objects: Studies in Phys. and Theor.. Stepanek J; Anzenbacher P; Sedlacek B. New York: Elsevier, 1987. 327-335