Christoph Proschel, Ph.D.

Christoph Proschel, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 633
Rochester, NY 14642

Office: (585) 273-5368
Lab: (585) 273-2416
Administrative: (585) 273-1440
Fax: (585) 273-1450

Journal Articles

Showing all 28 journal articles available.

2016 Feb
Campbell A, Bushman J, Munger J, Noble M, Pröschel C, Mayer-Pröschel M. "Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia." Glia. 2016 Feb; 64(2):227-39. Epub 2015 Oct 15.
2015 Nov 15
Campbell A, Krupp B, Bushman J, Noble M, Pröschel C, Mayer-Pröschel M. "A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden." Human molecular genetics. 2015 Nov 15; 24(22):6331-49. Epub 2015 Aug 26.
2015 Feb
Noble M, Mayer-Pröschel M, Li Z, Dong T, Cui W, Pröschel C, Ambeskovic I, Dietrich J, Han R, Miranda Yang Y, Folts C, Stripay J, Chen HY, Stevens BM. "Redox biology in normal cells and cancer: restoring function of the redox/Fyn/c-Cbl pathway in cancer cells offers new approaches to cancer treatment." Free radical biology & medicine. 2015 Feb; 79:300-23. Epub 2014 Dec 04.
2014 Apr
Proschel C, Stripay JL, Shih CH, Munger JC, Noble MD. "Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons." EMBO molecular medicine. 2014 Apr; 6(4):504-18. Epub 2014 Jan 29.
2014 Feb 12
Shih CH, Lacagnina M, Leuer-Bisciotti K, Pröschel C. "Astroglial-derived periostin promotes axonal regeneration after spinal cord injury." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 Feb 12; 34(7):2438-43.
2013 May 2
Noble M, Mayer-Pröschel M, Pröschel C. "iOPs: a new tool for studying myelin pathologies?" Cell stem cell. 2013 May 2; 12(5):503-4.
2011 Dec
Noble M, Mayer-Pröschel M, Davies JE, Davies SJ, Pröschel C. "Cell therapies for the central nervous system: how do we identify the best candidates?" Current opinion in neurology. 2011 Dec; 24(6):570-6.
2011 Oct
Noble M, Davies JE, Mayer-Pröschel M, Pröschel C, Davies SJ. "Precursor cell biology and the development of astrocyte transplantation therapies: lessons from spinal cord injury." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2011 Oct; 8(4):677-93.
2011 Mar 2
Davies SJ, Shih CH, Noble M, Mayer-Proschel M, Davies JE, Proschel C. "Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury." PloS one. 2011 Mar 2; 6(3):e17328. Epub 2011 Mar 02.
2011 Jan 7
Noble M, Pröschel C, Mayer-Pröschel M. "Oxidative-reductionist approaches to stem and progenitor cell function." Cell stem cell. 2011 Jan 7; 8(1):1-2.
2011 Jan
Nout YS, Culp E, Schmidt MH, Tovar CA, Pröschel C, Mayer-Pröschel M, Noble MD, Beattie MS, Bresnahan JC. "Glial restricted precursor cell transplant with cyclic adenosine monophosphate improved some autonomic functions but resulted in a reduced graft size after spinal cord contusion injury in rats." Experimental neurology. 2011 Jan; 227(1):159-71. Epub 2010 Oct 30.
2008 Sep 19
Davies JE, Pröschel C, Zhang N, Noble M, Mayer-Pröschel M, Davies SJ. "Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury." Journal of biology. 2008 Sep 19; 7(7):24. Epub 2008 Sep 19.
Davies JE; Proschel C; Zhang N; Noble M; Mayer-Proschel M; Davies SA. "Transplanted astrocytes derived from BMP or CNTF treated glial restricted precursors have opposite effects on recovery and allodynia after spinal cord injury". J Biol. 2008; 19(7): 24.
2007 Feb
Li Z, Dong T, Pröschel C, Noble M. "Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function." PLoS biology. 2007 Feb; 5(2):e35.
Li, Z.; Dong, T., Pröschel, C.; Noble, M. "Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function". PLoS Biology. 2007; 5(2): 35.
2006 May
Hyrien O.; Ambeskovic I.; Mayer-Pröschel M.; Noble M.; Yakovlev, A. "Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data". Theoretical Biology and Medical Modelling. 2006; 3. Link
Davies JE, Huang C, Proschel C, Noble M, Mayer-Proschel M, Davies SJ. "Astrocytes derived from glial-restricted precursors promote spinal cord repair." Journal of biology. 2006 5(3):7. Epub 2006 Apr 27.
2005 Mar
Dietrich J, Lacagnina M, Gass D, Richfield E, Mayer-Pröschel M, Noble M, Torres C, Pröschel C. "EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy." Nature medicine. 2005 Mar; 11(3):277-83. Epub 2005 Feb 20.
Noble,M.; Mayer-Proschel,M.; Proschel,C.;. "Redox regulation of precursor cell function: insights and paradoxes". Antioxidants & Redox Signalling. 2005; 7(11-12): 1456-1467. Link
Noble M, Mayer-Pröschel M, Pröschel C. "Redox regulation of precursor cell function: insights and paradoxes." Antioxidants & redox signaling. 2005 7(11-12):1456-67.
2004 Dec
Hill CE, Proschel C, Noble M, Mayer-Proschel M, Gensel JC, Beattie MS, Bresnahan JC. "Acute transplantation of glial-restricted precursor cells into spinal cord contusion injuries: survival, differentiation, and effects on lesion environment and axonal regeneration." Experimental neurology. 2004 Dec; 190(2):289-310.
2004 Jan 1
Noble M, Pröschel C, Mayer-Pröschel M. "Getting a GR(i)P on oligodendrocyte development." Developmental biology. 2004 Jan 1; 265(1):33-52.
2002 Jan 1
Gregori N, Pröschel C, Noble M, Mayer-Pröschel M. "The tripotential glial-restricted precursor (GRP) cell and glial development in the spinal cord: generation of bipotential oligodendrocyte-type-2 astrocyte progenitor cells and dorsal-ventral differences in GRP cell function." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Jan 1; 22(1):248-56.
2001 Sep
Herrera J, Yang H, Zhang SC, Proschel C, Tresco P, Duncan ID, Luskin M, Mayer-Proschel M. "Embryonic-derived glial-restricted precursor cells (GRP cells) can differentiate into astrocytes and oligodendrocytes in vivo." Experimental neurology. 2001 Sep; 171(1):11-21.
1996 Jul 12
Frangiskakis JM, Ewart AK, Morris CA, Mervis CB, Bertrand J, Robinson BF, Klein BP, Ensing GJ, Everett LA, Green ED, Pröschel C, Gutowski NJ, Noble M, Atkinson DL, Odelberg SJ, Keating MT. "LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition." Cell. 1996 Jul 12; 86(1):59-69.
1996 Jul
Tassabehji M, Metcalfe K, Fergusson WD, Carette MJ, Dore JK, Donnai D, Read AP, Pröschel C, Gutowski NJ, Mao X, Sheer D. "LIM-kinase deleted in Williams syndrome." Nature genetics. 1996 Jul; 13(3):272-3.
Mao X, Jones TA, Williamson J, Gutowski NJ, Pröschel C, Noble M, Sheer D. "Assignment of the human and mouse LIM-kinase genes (LIMK1; Limk1) to chromosome bands 7q11.23 and 5G1, respectively, by in situ hybridization." Cytogenetics and cell genetics. 1996 74(3):190-1.
1995 Oct 5
Pröschel C, Blouin MJ, Gutowski NJ, Ludwig R, Noble M. "Limk1 is predominantly expressed in neural tissues and phosphorylates serine, threonine and tyrosine residues in vitro." Oncogene. 1995 Oct 5; 11(7):1271-81.