R. James White, M.D., Ph.D.

R. James White, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 692
Rochester, NY 14642

Appointment: (585) 275-URMC (8762)

  • Accepting New Patients Accepting New Patients
  • Admits to Strong Memorial Hospital Admits to Strong Memorial Hospital
  • Admits to Highland Hospital Admits to Highland Hospital

Professional Bio

The overall goal of my clinical research and bench laboratory is to provide better care to patients with a rare disease of the lung blood vessels, pulmonary arterial hypertension (PAH). We provide care for patients from all over New York and central PA, and we use the full complement of approved PAH therapies. We also contribute actively to clinical research in hopes of better therapies with drugs that are already available. In my laboratory, we do experiments in animals and cells in an attempt to discover entirely new ways to treat this deadly disease.

Patient Care Bio

Dr. White's focus is to understand the vascular biology of pulmonary arterial hypertension (PAH) and to apply the best science in the care of patients. His lab uses a rat model of severe PAH (pneumonectomy and monocrotaline) and they measure the effects of PAH on exercise tolerance, hemodynamics, and angiography. They are testing novel small molecules that might be useful in treating patients with this devastating disease. Dr. White is currently treating ~130 patients for PAH with 30 patients on Remodulin or Flolan. We are actively enrolling in national clinical trials for PAH.

Awards & Honors (Local)

Parker B. Francis Fellowship in Pulmonary Biology, Francis Family Foundation 2005 - 2007
Buswell Fellowship, Department of Medicine, University of Rochester SMD 2003 - 2005
NIH Training Grant Multi-Disciplinary Training & Pulmonary Research, University of Rochester SMD 2001 - 2004
Alpha Omega Alpha, University of Pittsburgh 1996
NIH Medical Scientist Training Program, University of Pittsburgh 1990 - 1997
Phi Beta Kappa, Ohio State University 1990


Tissue Factor Pathway Inhibition as a Treatment Strategy for Severe Pulmonary Arterial Hypertension

United States Serial NO.: 11/576,773
Filed Date: October 7, 2005
Title: Treatment of Pulmonary Hylertension uisng An Agent that Inhibits a Tissue Factor Pathway
Invented by: R. James White, Mark Taubman

Current Appointments

Associate Professor (Part-Time) - Department of Medicine, Pulmonary Diseases and Critical Care (SMD) - Primary
Associate Professor (Part-Time) - Department of Pharmacology and Physiology (SMD)


Internal Medicine - American Board of Internal Medicine
Critical Care Medicine - American Board of Internal Medicine
Pulmonary Disease - American Board of Internal Medicine


MD | Medicine | Univ Pittsburgh Sch Medicine1997
PhD | Neuroscience | Univ Pittsburgh Sch Medicine1996
BS | Arts & Sciences | Ohio State University1990

Post-Doctoral Training & Residency

Fellowship in Pulmonary/Critical Care at University of Rochester, Dept. of Medicine07/01/2000 - 06/30/2003
Residency in Internal Medicine at University of Rochester, Dept. of Medicine06/24/1998 - 06/23/2000
Internship in Internal Medicine at University of Rochester, Dept. of Medicine06/24/1997 - 06/23/1998