Shannon Patrick Hilchey, Ph.D.

Shannon Patrick Hilchey, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 675
Rochester, NY 14642

Office: (585) 273-2187

Journal Articles

Showing all 22 journal articles available.

2016
Nedelkovska H, Rosenberg AF, Hilchey SP, Hyrien O, Burack WR, Quataert SA, Baker CM, Azadniv M, Welle SL, Ansell SM, Kim M, Bernstein SH. "Follicular Lymphoma Tregs Have a Distinct Transcription Profile Impacting Their Migration and Retention in the Malignant Lymph Node." PloS one. 2016 11(5):e0155347. Epub 2016 May 26.
2015 Feb
Kiebala M, Skalska J, Casulo C, Brookes PS, Peterson DR, Hilchey SP, Dai Y, Grant S, Maggirwar SB, Bernstein SH. "Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach." Experimental hematology. 2015 Feb; 43(2):89-99. Epub 2014 Oct 22.
2015
Wang J, Hilchey SP, Hyrien O, Huertas N, Perry S, Ramanunninair M, Bucher D, Zand MS. "Multi-Dimensional Measurement of Antibody-Mediated Heterosubtypic Immunity to Influenza." PloS one. 2015 10(6):e0129858. Epub 2015 Jun 23.
2015
Qiu X, Wu S, Hilchey SP, Thakar J, Liu ZP, Welle SL, Henn AD, Wu H, Zand MS. "Diversity in Compartmental Dynamics of Gene Regulatory Networks: The Immune Response in Primary Influenza A Infection in Mice." PloS one. 2015 10(9):e0138110. Epub 2015 Sep 28.
2015
Zand MS, Wang J, Hilchey S. "Graphical Representation of Proximity Measures for Multidimensional Data: Classical and Metric Multidimensional Scaling." The Mathematica journal. 2015 17Epub 2015 Sep 30.
2014
Brady MT, Hilchey SP, Hyrien O, Spence SA, Bernstein SH. "Mesenchymal stromal cells support the viability and differentiation of follicular lymphoma-infiltrating follicular helper T-cells." PloS one. 2014 9(5):e97597. Epub 2014 May 16.
2014
Miao H, Sangster MY, Livingstone AM, Hilchey SP, Zhang L, Topham DJ, Mosmann TR, Holden-Wiltse J, Perelson AS, Wu H, Zand MS. "Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection." PloS one. 2014 9(8):e104781. Epub 2014 Aug 29.
2012 Apr 5
Bernstein SH, Venkatesh S, Li M, Lee J, Lu B, Hilchey SP, Morse KM, Metcalfe HM, Skalska J, Andreeff M, Brookes PS, Suzuki CK. "The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives." Blood. 2012 Apr 5; 119(14):3321-9. Epub 2012 Feb 08.
2011 Sep 29
Hilchey SP, Rosenberg AF, Hyrien O, Secor-Socha S, Cochran MR, Brady MT, Wang JC, Sanz I, Burack WR, Quataert SA, Bernstein SH. "Follicular lymphoma tumor-infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation." Blood. 2011 Sep 29; 118(13):3591-602. Epub 2011 Aug 05.
2009 Nov 15
Hilchey SP, Kobie JJ, Cochran MR, Secor-Socha S, Wang JC, Hyrien O, Burack WR, Mosmann TR, Quataert SA, Bernstein SH. "Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness." The Journal of immunology : official journal of the American Association of Immunologists. 2009 Nov 15; 183(10):6157-66. Epub 2009 Oct 28.
2009 Apr 16
Hilchey SP, Hyrien O, Mosmann TR, Livingstone AM, Friedberg JW, Young F, Fisher RI, Kelleher RJ, Bankert RB, Bernstein SH. "Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab." Blood. 2009 Apr 16; 113(16):3809-12. Epub 2009 Feb 04.
2009
Skalska J, Brookes PS, Nadtochiy SM, Hilchey SP, Jordan CT, Guzman ML, Maggirwar SB, Briehl MM, Bernstein SH. "Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide." PloS one. 2009 4(12):e8115. Epub 2009 Dec 02.
2007 Apr 1
Hilchey SP, De A, Rimsza LM, Bankert RB, Bernstein SH. "Follicular lymphoma intratumoral CD4+CD25+GITR+ regulatory T cells potently suppress CD3/CD28-costimulated autologous and allogeneic CD8+CD25- and CD4+CD25- T cells." The Journal of immunology : official journal of the American Association of Immunologists. 2007 Apr 1; 178(7):4051-61.
2007 Feb 15
Brookes PS, Morse K, Ray D, Tompkins A, Young SM, Hilchey S, Salim S, Konopleva M, Andreeff M, Phipps R, Bernstein SH. "The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore." Cancer research. 2007 Feb 15; 67(4):1793-802.
2007
Hilchey SP, Bernstein SH. "Use of CFSE to monitor ex vivo regulatory T-cell suppression of CD4+ and CD8+ T-cell proliferation within unseparated mononuclear cells from malignant and non-malignant human lymph node biopsies." Immunological investigations. 2007 36(5-6):629-48.
2006 Sep
Ray DM, Morse KM, Hilchey SP, Garcia TM, Felgar RE, Maggirwar SB, Phipps RP, Bernstein SH. "The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway." Experimental hematology. 2006 Sep; 34(9):1202-11.
2005
Shah, S., Divekar A.A., Hilchey, S.P., Cho, H.M., Newman, C.L., Shin, S.U., Nechustan, H., Challita-Eid, P.M., Segal, B.M., Yi, K.H., Rosenblatt, J.D. "Increased rejection of primary tumors in mice lacking B cells: Inhibition of anti-tumor CTL and TH1 cytokine responses by B cells." International Journal of Cancer. 2005; 117: 574-586. Link
2001 Jul 15
Tolba KA, Bowers WJ, Hilchey SP, Halterman MW, Howard DF, Giuliano RE, Federoff HJ, Rosenblatt JD. "Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia." Blood. 2001 Jul 15; 98(2):287-95.
1998 Oct 1
Challita-Eid PM, Abboud CN, Morrison SL, Penichet ML, Rosell KE, Poles T, Hilchey SP, Planelles V, Rosenblatt JD. "A RANTES-antibody fusion protein retains antigen specificity and chemokine function." The Journal of immunology : official journal of the American Association of Immunologists. 1998 Oct 1; 161(7):3729-36.
1997 Aug 8
Hilchey SP, Wu L, Koudelka GB. "Recognition of nonconserved bases in the P22 operator by P22 repressor requires specific interactions between repressor and conserved bases." The Journal of biological chemistry. 1997 Aug 8; 272(32):19898-905.
1997 Jan 17
Hilchey SP, Koudelka GB. "DNA-based loss of specificity mutations. Effects of DNA sequence on the contacted and non-contacted base preferences of bacteriophage P22 repressor." The Journal of biological chemistry. 1997 Jan 17; 272(3):1646-53.
1996
Koudelka, G.B., Bell, A.C., Hilchey, S.P. "Indirect Effects of DNA Sequence of Protein-DNA Interactions." Biological Structure and Dynamics. 1996; 1: 1-19. Link

Books

1997
Hilchey, S.P., Xu, J., Koudelka, G.B.. "Indirect Effects of DNA Sequence on Transcriptional Activation by Prokaryotic DNA Binding Proteins.". Nucleic Acids & Molecular Biology. : Mechanisms in Transcription, 1997.