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Vyacheslav A. Korshunov, Ph.D.

Contact Information

Phone Numbers

Administrative: (585) 276-1530

Office: (585) 276-7705

Fax: (585) 276-7698

Research Labs

Dr. Korshunov's major focus is the understanding of mechanisms that regulate the structure of blood vessels (a process we call "vascular remodeling") that could prevent cardiovascular outcomes

Lab: (585) 276-7716

Visit Lab Website

Research Network

Biography

Professional Background

Vyacheslav "Slava" Korshunov, Ph.D. is an Assistant Professor of Medicine in the Aab Cardiovascular Research Institute at the University of Rochester School of Medicine and Dentistry. Dr. Korshunov recieved his Ph.D. in Pharmacy (Pharmacology) from The Pyatigorsk State Academy of Pharmacy (Russia) in 2000. He completed his post-doctoral training in vascular biology in Dr. Bradford Berk's laboratory in the Center for Cardiovascular Research at the University of Rochester in 2001-2003. Dr. Korshunov established his own independent laboratory in the University of Rochester's Aab Cardiovascular Research Institute. He serves on the Editorial Board of Atherosclerosis, Thrombosis and Vascular Biology. His current research interests include two major topics (systems genetics and candidate gene approaches) to understand mechanisms of vascular remodeling in response to hemodynamic stimuli and their impact on cardiovascular diseases.

Research

Dr. Korshunov's research focuses on vascular biology. First project examines a candidate gene Axl, a receptor tyrosine kinase, in hypertension. Axl is a very promising candidate that regulates both vascular and immune cells in hypertension. Our studies will refine the current concept of the immune response in hypertension. A second project aims to discover causal genes and key pathways of the Glagov phenomenon. Originally described in atherosclerotic patients, Glagov phenomenon is a type of vascular remodeling that preserves the ability of blood to get through the artery. Therapeutic manipulation with vascular remodeling can be crucial for outcomes of cardiovascular diseases, such as heart attacks, strokes and peripheral artery diseases

Credentials

Faculty Appointments

Education

2001-2003
Postdoctoral Training | University of Rochester, Aab Cardiovascular Research
Cardiovascular Research

2000
Ph.D. in Pharmaceutical Sciences (Pharmacology) | Pyatigorsk State Academy of Pharmacy

1999
Masters in Biology | Puschino State University, Pharmacology Group

1997
Diploma in Pharmacy with Honor | Pyatigorsk State Academy of Pharmacy

Awards

2006 - 2006
Finalist of the Junior Investigator Award
Sponsor: NAVBO
Location: San Francisco, CA

2005 - 2005
Finalist of Irvine H. Page Young Investigator Research Award
Sponsor: AHA Council on ATVB
Location: Washington, DC

2003 - 2003
Research Recognition Award
Sponsor: American Physiological Society
Location: San Diego, CA

2001 - 2001
Diploma at the II Russian Conference of Young Scientists
Location: Moscow, Russia

2000 - 2000
A Travel Award for Young Scientist
Location: Goteborg, Sweden

1999 - 1999
A Diploma in The Competition Young Scientist (Pharmacist)
Location: Moscow, Russia

1999
2nd place in the Competition Young Scientist (Pharmacist)
Sponsor: 6th National Russian Congress Man and Medicine
Location: Moscow, Russia

1996 - 1996
Honor at the Competition Young Scientists
Location: Moscow, Russia

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Publications

Journal Articles

5/23/2013
Shi G, Field DJ, Long X, Mickelsen D, Ko KA, Ture S, Korshunov VA, Miano JM, Morrell CN. "Platelet factor 4 mediates vascular smooth muscle cell injury responses." Blood.. 2013 May 23; 121(21):4417-27. Epub 2013 Apr 08.

5/2013
Pang J, Xu X, Wang X, Majumder S, Wang J, Korshunov VA, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration." Arteriosclerosis, thrombosis, and vascular biology.. 2013 May 0; 33(5):999-1005. Epub 2013 Feb 21.

5/2013
Smolock EM, Machleder DE, Korshunov VA, Berk BC. "Identification of a genetic locus on chromosome 11 that regulates leukocyte infiltration in mouse carotid artery." Arteriosclerosis, thrombosis, and vascular biology.. 2013 May 0; 33(5):1014-9. Epub 2013 Feb 28.

Books & Chapters

2010
Chapter Title: Apoptosis and vascular disease
Book Title: Modern Insights Into Disease From Molecules to Man
Author List: Korshunov, V.A.
Edited By: Victor R Preedy
Published By: Apoptosis2010

2006
Chapter Title: Flow-induced Vascular Remodeling
Book Title: In A Handbook of Mouse Models for Cardiovascular Disease
Author List: Korshunov, VA.; Berk, BC.
Edited By: Quingbo Xu
Published By: John Wiley & Sons, Ltd.2006

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