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Elena P. Bulgac, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-6710

Fax: (585) 271-2683

Research Labs

Biography

Research

Chromosomes instability of human fungal pathogen Candida albicans. Survival due to specific chromosome rearrangements.

Candida albicans is a unicellular budding fungus that forms part of normal gut or genitalia microflora. In immunocompromized humans, however, C. albicans becomes an important opportunistic pathogen that can cause mortality. C. albicans is unique among other fungal pathogens by having an ability to infect divers sites of human body, including skin, nails, mucosal surfaces, as well as any other tissues or inner organs. In the laboratory, this fungus demonstrates an impressive ability to flourish under extreme pH and temperatures, as well as in other extreme environments. C. albicans possesses an acute ability to counter act the environmental stresses and to mount adequate phenotypic responses.

Credentials

Education

1971
MS | USSR - Non-Medical School
Genetics

1974
PhD | USSR - Non-Medical School
Genetics

Publications

Journal Articles

12/2021
Lowman DW, Sameer Al-Abdul-Wahid M, Ma Z, Kruppa MD, Rustchenko E, Williams DL. "Glucan and glycogen exist as a covalently linked macromolecular complex in the cell wall of and other species." . 2021 Dec 0; 7:100061. Epub 2021 Aug 27.

5/2021
Sah SK, Hayes JJ, Rustchenko E. "The role of aneuploidy in the emergence of echinocandin resistance in human fungal pathogen Candida albicans." PLoS pathogens.. 2021 May 0; 17(5):e1009564. Epub 2021 May 27.

7/5/2019
Tucker C, Bhattacharya S, Wakabayashi H, Bellaousov S, Kravets A, Welle SL, Myers J, Hayes JJ, Bulger M, Rustchenko E. "Author Correction: Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants." Scientific reports.. 2019 Jul 5; 9(1):10019. Epub 2019 Jul 05.

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