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Elena P. Bulgac, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-6710

Fax: (585) 271-2683

Research Labs

Faculty Appointments

Biography

Research

Chromosomes instability of human fungal pathogen Candida albicans. Survival due to specific chromosome rearrangements.

Candida albicans is a unicellular budding fungus that forms part of normal gut or genitalia microflora. In immunocompromized humans, however, C. albicans becomes an important opportunistic pathogen that can cause mortality. C. albicans is unique among other fungal pathogens by having an ability to infect divers sites of human body, including skin, nails, mucosal surfaces, as well as any other tissues or inner organs. In the laboratory, this fungus demonstrates an impressive ability to flourish under extreme pH and temperatures, as well as in other extreme environments. C. albicans possesses an acute ability to counter act the environmental stresses and to mount adequate phenotypic responses.

Credentials

Education

1971
MS | USSR - Non-Medical School
Genetics

1974
PhD | USSR - Non-Medical School
Genetics

Publications

Journal Articles

4/2018
Suwunnakorn S, Wakabayashi H, Kordalewska M, Perlin DS, Rustchenko E. "and Genes of Opportunistic Human Pathogen Candida albicans Influence Echinocandin Susceptibility." Antimicrobial agents and chemotherapy.. 2018 Apr 0; 62(4)Epub 2018 Mar 27.

4/2018
Yang F, Zhang L, Wakabayashi H, Myers J, Jiang Y, Cao Y, Jimenez-Ortigosa C, Perlin DS, Rustchenko E. "Correction for Yang et al., "Tolerance to Caspofungin in Candida albicans Is Associated with at Least Three Distinctive Mechanisms That Govern Expression of Genes and Cell Wall Remodeling"." Antimicrobial agents and chemotherapy.. 2018 Apr 0; 62(4)Epub 2018 Mar 27.

1/26/2018
Tucker C, Bhattacharya S, Wakabayashi H, Bellaousov S, Kravets A, Welle SL, Myers J, Hayes JJ, Bulger M, Rustchenko E. "Transcriptional Regulation on Aneuploid Chromosomes in Divers Candida albicans Mutants." Scientific reports.. 2018 Jan 26; 8(1):1630. Epub 2018 Jan 26.

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