Skip to main content
Explore URMC

Jing Wang, B.Med., Ph.D.

Contact Information

Phone Numbers



1. Macrophage mediated fungal clearance and lung injury during
Pneumocystis pneumonia
2. Mechanism of immune mediated lung injury during infectious diseases
3. Seeking new strategies to treat inflammatory lung diseases

Pneumocystis is an opportunistic fungal respiratory pathogen that causes life-threatening pneumonia in patients suffering from defects in cell-mediated immunity, including those with acquired immunodeficiency syndrome (AIDS) and immunosuppression secondary to chemotherapy or organ transplantation. Despite dramatic advances in health care and the availability of antibiotics to treat this infection, mortality rates have improved little over the past 25 years. Pneumocystis carinii pneumonia remains a leading cause of death among HIV-infected patients and a significant cause of AIDS-related mortality and morbidity. This highlights the need for better understanding of the pathogenesis of the disease, and underscores the necessity of investigating new therapeutic strategies.

My research uses Pneumocystis pneumonia as one of the models to study the mechanisms of lung injury. I use a variety of immunology, imaging, and cell biological techniques to study the role of alveolar macrophage phenotype during inflammatory lung diseases.

The specific goals of my research are to: 1) determine the functional changes in alveolar macrophages during inflammatory lung diseases, and 2) evaluate the feasibility of using specific macrophage phenotype subsets as adjunctive treatments to ameliorate inflammatory lung diseases.



M.D. Equivalency | Chongqing Medical University

Master | Chongqing Medical University
Clinical Immunology

PhD | School of Medicine and Dentistry, University of Rochester
Medical Microbiology and Immunology Graduate Program

Post-doctoral Training & Residency

1995 - 1998
Internship, Children's Hospital, Chongqing Medical University, Chongqing, Sirchuan, China.

1994 - 1995
Clerkship, Children's Hospital; The Second Affiliated Hospital; The Third People's Hospital, Chongqing Medical University, Chongqing, China

0 - 2001
Research Fellowship, Department of Pediatrics, West China Second University Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China

0 - 2001
Residency, Department of Pediatrics, West China Second University Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China

VIEW ALL expand_more


Junior Faculty Travel Grant
Sponsor: 2010 American Association of Immunologist, 97th AAI Annual Mtg
Location: Baltimore, MD

Travel Award
Sponsor: 2009 American Thoracic Society International Conference
Location: San Diego, CA

Travel Award
Sponsor: X International Workshops on Opportunistic Protists
Location: Boston, MA

New York State Blavatnik Award for Young Scientists (Nominee)
Sponsor: University of Rochester School of Medicine and Dentistry

Travel Award
Sponsor: The 22nd International Congress of Pediatrics
Location: Amsterdam, Holland

1990 - 1995
Dean's Scholarship for Excellent Academic Achievement(five-time recipient)
Location: Chongqing Medical University

VIEW ALL expand_more


Journal Articles

Bello-Irizarry SN; Wang J; Olsen K; Gigliotti F; Wright TW. "MyD88 signaling regulates both host defense and immunopathogenesis during Pneumocystis infection". J Immunol. 2014; : 282-92.

Bello-Irizarry SN, Wang J, Olsen K, Gigliotti F, Wright TW. "The alveolar epithelial cell chemokine response to pneumocystis requires adaptor molecule MyD88 and interleukin-1 receptor but not toll-like receptor 2 or 4." Infection and immunity.. 2012 Nov; 80(11):3912-20. Epub 2012 Aug 27.

Wang J, Wright TW, Gigliotti F. "Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia." Interdisciplinary perspectives on infectious diseases. 2011 2011:918038. Epub 2011 Aug 29.