Clement L. Ren, M.D.

Clement L. Ren, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 667
Rochester, NY 14642

Office: (585) 275-2464
Fax: (585) 275-8706

Journal Articles

Showing all 39 journal articles available.

2015 Sep
Rosenfeld M, VanDevanter DR, Ren CL, Elkin EP, Pasta DJ, Konstan MW, Morgan WJ, . "Decline in lung function does not predict future decline in lung function in cystic fibrosis patients." Pediatric pulmonology. 2015 Sep; 50(9):856-62. Epub 2015 Jun 18.
2015 Aug
Cogen J, Emerson J, Sanders DB, Ren C, Schechter MS, Gibson RL, Morgan W, Rosenfeld M, . "Risk factors for lung function decline in a large cohort of young cystic fibrosis patients." Pediatric pulmonology. 2015 Aug; 50(8):763-70. Epub 2015 Jun 09.
2015 Aug
Kay DM, Langfelder-Schwind E, DeCelie-Germana J, Sharp JK, Maloney B, Tavakoli NP, Saavedra-Matiz CA, Krein LM, Caggana M, Kier C, . "Utility of a very high IRT/No mutation referral category in cystic fibrosis newborn screening." Pediatric pulmonology. 2015 Aug; 50(8):771-80. Epub 2015 Jun 22.
2015 Aug
Sanders DB, Emerson J, Ren CL, Schechter MS, Gibson RL, Morgan W, Rosenfeld M, . "Early Childhood Risk Factors for Decreased FEV1 at Age Six to Seven Years in Young Children with Cystic Fibrosis." Annals of the American Thoracic Society. 2015 Aug; 12(8):1170-6.
2015 Jun
Ren CL, Fink AK, Petren K, Borowitz DS, McColley SA, Sanders DB, Rosenfeld M, Marshall BC. "Outcomes of infants with indeterminate diagnosis detected by cystic fibrosis newborn screening." Pediatrics. 2015 Jun; 135(6):e1386-92. Epub 2015 May 11.
2015 May
Maitre NL, Ballard RA, Ellenberg JH, Davis SD, Greenberg JM, Hamvas A, Pryhuber GS. "Respiratory consequences of prematurity: evolution of a diagnosis and development of a comprehensive approach." Journal of perinatology : official journal of the California Perinatal Association. 2015 May; 35(5):313-21. Epub 2015 Mar 26.
Pryhuber GS, Maitre NL, Ballard RA, Cifelli D, Davis SD, Ellenberg JH, Greenberg JM, Kemp J, Mariani TJ, Panitch H, Ren C, Shaw P, Taussig LM, Hamvas A, . "Prematurity and respiratory outcomes program (PROP): study protocol of a prospective multicenter study of respiratory outcomes of preterm infants in the United States." BMC pediatrics. 2015 15:37. Epub 2015 Apr 10.
2014 Aug
Ren CL, Konstan MW, Rosenfeld M, Pasta DJ, Millar SJ, Morgan WJ, . "Early childhood wheezing is associated with lower lung function in cystic fibrosis." Pediatric pulmonology. 2014 Aug; 49(8):745-50. Epub 2013 Oct 01.
2014 Jul
Boyle MP, Bell SC, Konstan MW, McColley SA, Rowe SM, Rietschel E, Huang X, Waltz D, Patel NR, Rodman D, . "A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial." The Lancet. Respiratory medicine. 2014 Jul; 2(7):527-38. Epub 2014 Jun 24.
Nevin MA, Daines CL, Redding GJ, Ren CL, Ratjen FA, Shah AV, Hiranrattana A, Alexiou S, Bansal M, Pizarro-Gamboa ME, Panitch HB. "ATS core curriculum 2014: part IV. Pediatric pulmonary medicine." Annals of the American Thoracic Society. 2014 11(10):1633-9.
2013 Sep
Sawicki GS, Ren CL, Konstan MW, Millar SJ, Pasta DJ, Quittner AL, . "Treatment complexity in cystic fibrosis: trends over time and associations with site-specific outcomes." Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 2013 Sep; 12(5):461-7. Epub 2013 Jan 24.
2013 Apr
Rosenfeld M, Allen J, Arets BH, Aurora P, Beydon N, Calogero C, Castile RG, Davis SD, Fuchs S, Gappa M, Gustaffson PM, Hall GL, Jones MH, Kirkby JC, Kraemer R, Lombardi E, Lum S, Mayer OH, Merkus P, Nielsen KG, Oliver C, Oostveen E, Ranganathan S, Ren CL, Robinson PD, Seddon PC, Sly PD, Sockrider MM, Sonnappa S, Stocks J, Subbarao P, Tepper RS, Vilozni D, . "An official American Thoracic Society workshop report: optimal lung function tests for monitoring cystic fibrosis, bronchopulmonary dysplasia, and recurrent wheezing in children less than 6 years of age." Annals of the American Thoracic Society. 2013 Apr; 10(2):S1-S11.
2012 Oct
McColley SA, Ren CL, Schechter MS, Regelmann WE, Pasta DJ, Konstan MW, . "Risk factors for onset of persistent respiratory symptoms in children with cystic fibrosis." Pediatric pulmonology. 2012 Oct; 47(10):966-72. Epub 2012 Feb 22.
2012 Aug
Emond MJ, Louie T, Emerson J, Zhao W, Mathias RA, Knowles MR, Wright FA, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC, , , Gibson RL, Bamshad MJ. "Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis." Nature genetics. 2012 Aug; 44(8):886-9. Epub 2012 Jul 08.
2012 Jul
Ren CL, Konstan MW, Yegin A, Rasouliyan L, Trzaskoma B, Morgan WJ, Regelmann W, . "Multiple antibiotic-resistant Pseudomonas aeruginosa and lung function decline in patients with cystic fibrosis." Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 2012 Jul; 11(4):293-9. Epub 2012 Mar 23.
2012 Jun 6
Rosenfeld M, Ratjen F, Brumback L, Daniel S, Rowbotham R, McNamara S, Johnson R, Kronmal R, Davis SD, . "Inhaled hypertonic saline in infants and children younger than 6 years with cystic fibrosis: the ISIS randomized controlled trial." JAMA. 2012 Jun 6; 307(21):2269-77.
2012 Jun
Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Brumback L, Castile R, Hart MA, Hiatt P, Kloster M, Johnson R, Jones P, Davis SD. "Lung function distinguishes preschool children with CF from healthy controls in a multi-center setting." Pediatric pulmonology. 2012 Jun; 47(6):597-605. Epub 2011 Nov 11.
2012 Jun
Ren CL, Rosenfeld M, Mayer OH, Davis SD, Kloster M, Castile RG, Hiatt PW, Hart M, Johnson R, Jones P, Brumback LC, Kerby GS. "Analysis of the associations between lung function and clinical features in preschool children with cystic fibrosis." Pediatric pulmonology. 2012 Jun; 47(6):574-81. Epub 2011 Nov 11.
EE Scarlett, S Walker, A Rovitelli, and CL Ren. "Tidal breathing responses to albuterol and normal saline in infants with viral bronchiolitis." Pediatr Allergy Immunol Pulmonol. 2012; 25: 220-5.
2011 Nov
Ren CL, Desai H, Platt M, Dixon M. "Clinical outcomes in infants with cystic fibrosis transmembrane conductance regulator (CFTR) related metabolic syndrome." Pediatric pulmonology. 2011 Nov; 46(11):1079-84. Epub 2011 Apr 29.
2010 Sep
Rosenfeld M, Emerson J, McNamara S, Joubran K, Retsch-Bogart G, Graff GR, Gutierrez HH, Kanga JF, Lahiri T, Noyes B, Ramsey B, Ren CL, Schechter M, Morgan W, Gibson RL, . "Baseline characteristics and factors associated with nutritional and pulmonary status at enrollment in the cystic fibrosis EPIC observational cohort." Pediatric pulmonology. 2010 Sep; 45(9):934-44.
2008 Nov
Sawicki GS, Rasouliyan L, Pasta DJ, Regelmann WE, Wagener JS, Waltz DA, Ren CL, . "The impact of incident methicillin resistant Staphylococcus aureus detection on pulmonary function in cystic fibrosis." Pediatric pulmonology. 2008 Nov; 43(11):1117-23.
2008 Aug
VanDevanter DR, Rasouliyan L, Murphy TM, Morgan WJ, Ren CL, Konstan MW, Wagener JS, . "Trends in the clinical characteristics of the U.S. cystic fibrosis patient population from 1995 to 2005." Pediatric pulmonology. 2008 Aug; 43(8):739-44.
2008 Jul
Giusti R, . "Elevated IRT levels in African-American infants: implications for newborn screening in an ethnically diverse population." Pediatric pulmonology. 2008 Jul; 43(7):638-41.
R Giusti and the New York State Cystic Fibrosis Newborn Screening Consortium (CL Ren, member). "Elevated IRT levels in african-american infants: implications for newborn screening in an ethnically diverse population." Pediatr Pulmonol. 2008; 43(7): 638–641. Link
Ren CL, Pasta DJ, Rasouliyan L, Wagener JS, Konstan MW, Morgan WJ, . "Relationship between inhaled corticosteroid therapy and rate of lung function decline in children with cystic fibrosis." The Journal of pediatrics. 2008 153(6):746-51. Epub 2008 Aug 30.
2007 Jun
Ren CL, Morgan WJ, Konstan MW, Schechter MS, Wagener JS, Fisher KA, Regelmann WE, . "Presence of methicillin resistant Staphylococcus aureus in respiratory cultures from cystic fibrosis patients is associated with lower lung function." Pediatric pulmonology. 2007 Jun; 42(6):513-8.
2007 Mar
Padman R, McColley SA, Miller DP, Konstan MW, Morgan WJ, Schechter MS, Ren CL, Wagener JS, . "Infant care patterns at epidemiologic study of cystic fibrosis sites that achieve superior childhood lung function." Pediatrics. 2007 Mar; 119(3):e531-7.
2006 Apr
Ren CL, Brucker JL, Rovitelli AK, Bordeaux KA. "Changes in lung function measured by spirometry and the forced oscillation technique in cystic fibrosis patients undergoing treatment for respiratory tract exacerbation." Pediatric pulmonology. 2006 Apr; 41(4):345-9.
2005 Sep
Ang JY, Ray-Mazumder S, Nachman SA, Rongkavilit C, Asmar BI, Ren CL. "Use of complementary and alternative medicine by parents of children with HIV infection and asthma and well children." Southern medical journal. 2005 Sep; 98(9):869-75.
2002 Mar
Talmaciu I, Ren CL, Kolb SM, Hickey E, Panitch HB. "Pulmonary function in technology-dependent children 2 years and older with bronchopulmonary dysplasia." Pediatric pulmonology. 2002 Mar; 33(3):181-8.
2000 Nov
Geha RS, Beiser A, Ren C, Patterson R, Greenberger PA, Grammer LC, Ditto AM, Harris KE, Shaughnessy MA, Yarnold PR, Corren J, Saxon A. "Multicenter, double-blind, placebo-controlled, multiple-challenge evaluation of reported reactions to monosodium glutamate." The Journal of allergy and clinical immunology. 2000 Nov; 106(5):973-80.
1995 Feb
Loh RK, Jabara HH, Ren CL, Fu SM, Vercelli D, Geha RS. "Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cells." Immunology letters. 1995 Feb; 45(1-2):99-106.
1994 Nov
Ren CL, Fu SM, Geha RS. "Protein tyrosine kinase activation and protein kinase C translocation are functional components of CD40 signal transduction in resting human B cells." Immunological investigations. 1994 Nov; 23(6-7):437-48.
1994 Oct
Loh RK, Jabara HH, Ren CL, Fu SM, Geha RS. "Role of protein tyrosine kinases in CD40/interleukin-4-mediated isotype switching to IgE." The Journal of allergy and clinical immunology. 1994 Oct; 94(4):784-92.
1994 Feb 1
Ren CL, Morio T, Fu SM, Geha RS. "Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2." The Journal of experimental medicine. 1994 Feb 1; 179(2):673-80.
1988 Oct
Fernandez-Checa JC, Ren C, Aw TY, Ookhtens M, Kaplowitz N. "Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytes." The American journal of physiology. 1988 Oct; 255(4 Pt 1):G403-8.
1986 Feb
Aw TY, Ookhtens M, Ren C, Kaplowitz N. "Kinetics of glutathione efflux from isolated rat hepatocytes." The American journal of physiology. 1986 Feb; 250(2 Pt 1):G236-43.
1985 May 17
Forte TM, Luming Ren C, Nordhausen RW, Nichols AV. "Formation of phospholipid-rich HDL: a model for square-packing lipoprotein particles found in interstitial fluid and in abetalipoproteinemic plasma." Biochimica et biophysica acta. 1985 May 17; 834(3):386-95.


CZ Marcus and CL Ren.. "Allergy/Immunology Testing in the Evaluation of Pediatric Respiratory Disease". Diagnostic Techniques for the Pediatric Pulmonologist.. SD Davis, AC Koumbourlis, E Eber. : Springer, 2013.
CL Ren. "Pulmonary Complications of Immunodeficiency". AAP Manual of Pediatric Pulmonology. M Light. Elk Grove Village: American Academy of Pediatrics, 2011.
KZ Voter, AM McMullen, and CL Ren. "Cystic Fibrosis". Textbook of Adolescent Healthcare. MM Fisher, M Alderman, RE Kreipe, and WD Rosenfeld,. Elk Grove Village: American Academy of Pediatrics, 2011.
F Rezaee and CL Ren. "Preschool Pulmonary Function Testing in CF ,". Lung Biology in Health and Disease: Cystic Fibrosis. HB Panitch, R Rubenstein. New York: Informa Healthcare, 2010.
CL Ren and CB Hall. "Bronchiolitis". BMJ clinical monograph. : BMJ, 2008.
A.C. Patel and C.L. Ren. "Pulmonary complications of immunodeficiency". Requisites in Pediatrics. H.B Panitch. Philadelphia, PA: Elsevier Press, 2005.