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Rashid Deane, B.Sc., Ph.D.

Contact Information

Phone Numbers

Office: (585) 273-5377

Biography

Research

Research interest includes the following:

1) Control of the brain microenvironment (Blood-brain barrier, choroid plexus and cerebrospinal fluid).

2) Metals in health and disease.

3) Aging and neurodegenerative diseases (e.g. Alzheimer's disease).

Credentials

Education

1973
BSc | Bedford College, University of London
Physiology

1983
PhD | St. Thomas's Hospital Medical School
Neuroscience

Post-doctoral Training & Residency

1984 - 1987
Postdoctoral Research Fellow, King's College London, England

1982 - 1983
Postdoctoral Research Associate; University of Hull; Hull, UK

Awards

2001
Wellcome Trust Travel Award
Sponsor: Columbia University
Location: New York, NY

1993
1993 Performance Indicator Award
Sponsor: School of Chemical and Life Sciences /
Location: London, England

1990 - 2001
Science and Engineering Research Council (SERC) Awards
Sponsor: Agency for Science, Technology and Research
Location: Singapore

1974 - 1977
Medical Research Council (MRC, England) Scholar

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Patents

Patent Title: Soluble Low-Density Lipoprotein Receptor Related Protein Binds Directly to Alzheimer's Amyloid-beta Peptide
Patent #: 7,608,586
Issue Date: Oct 27, 2009
Country: United States
Invented By: Rashid Deane, Berislav V Zlokovic

Patent Title: Methods for Evaluating Brain-Wide Paravascular Pathway for Waste Clearance Function and Methods for Treating Neurodegenerative Disorders Based Thereon
Patent #: 6382232
Issue Date: Aug 10, 2018
Country: Japan
Invented By: Helene Benveniste, Rashid Deane, Jeffrey J Iliff, Maiken Nedergaard

Patent Title: Methods for Evaluating Brain-Wide Paravascular Pathway for Waste Clearance Function and Methods for Treating Neurodegenerative Disorders Based Thereon
Patent #: 9,901,650
Issue Date: Feb 27, 2018
Country: United States
Invented By: Helene Benveniste, Rashid Deane, Jeffrey J Iliff, Maiken Nedergaard

Patent Title: Inhibiting Amyloid-Beta Peptide/RAGE Interaction at the Blood-Brain Barrier
Patent #: 8,778,985
Issue Date: Jul 15, 2014
Country: United States
Invented By: Rashid Deane, Benjamin Locke Miller, Berislav V Zlokovic

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Publications

Journal Articles

11/22/2021
Brady M, McQuaid C, Solorzano A, Johnson A, Combs A, Venkatraman C, Rahman A, Leyva H, Kwok WE, Wood RW, Deane R. "Spike protein multiorgan tropism suppressed by antibodies targeting SARS-CoV-2." Communications biology.. 2021 Nov 22; 4(1):1318. Epub 2021 Nov 22.

9/3/2021
Deane R. "Response to the letter, entitled "Role of hemagglutinin esterase protein in neurological manifestation of COVID-19"." Fluids and barriers of the CNS. 2021 Sep 3; 18(1):41. Epub 2021 Sep 03.

7/14/2021
McQuaid C, Brady M, Deane R. "SARS-CoV-2: is there neuroinvasion?" Fluids and barriers of the CNS. 2021 Jul 14; 18(1):32. Epub 2021 Jul 14.

Books & Chapters

1990
Chapter Title: Lead and the Brain
Book Title: Pathophysiology of the blood-brain barrier : long term consequences of barrier d
Author List: Deane, R.; Bradbury, M. W. B.
Edited By: Johansson, B. B.; Owman, C.; Widner, H.
Published By: Elsevier 1990 in New York

1987
Chapter Title: Is Pulsation Important for the Brain?
Book Title: Peptide and amino acid transport mechanisms in the central nervous system
Author List: Deane, R.; Bradbury, M. W. B.
Edited By: Rakic, L.
Published By: Macmillan 1987

1985
Chapter Title: Why is the Concentration of Glucose in CSF Less Than in Plasma?
Book Title: Carrier mediated transport of solutes from blood to tissue
Author List: Deane, R.; Segal, M. W.
Edited By: Yudilevich, D.L.; Mann, G.E.
Published By: Longman 1985 in New York

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