Rashid Deane, B.Sc., Ph.D.

Contact Information

Phone Numbers

Office: (585) 273-5377

Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 670
Rochester, NY 14642

Faculty Appointments

Research Professor (Part-Time) - Department of Neuroscience (SMD)

Biography

Research

Research interest includes the following:

1) Control of the brain microenvironment (Blood-brain barrier, choroid plexus and cerebrospinal fluid).

2) Metals in health and disease.

3) Aging and neurodegenerative diseases (e.g. Alzheimer's disease).

Credentials

Education

1973
BSc | Bedford College, University of London
Physiology

1983
PhD | St. Thomas's Hospital Medical School
Neuroscience

Post-doctoral Training & Residency

1984 - 1987
Postdoctoral Research Fellow, King's College London, England

1982 - 1983
Postdoctoral Research Associate; University of Hull; Hull, UK

Awards

2001
Wellcome Trust Travel Award
Sponsor: Columbia University
Location: New York, NY

1993
1993 Performance Indicator Award
Sponsor: School of Chemical and Life Sciences /
Location: London, England

1990 - 2001
Science and Engineering Research Council (SERC) Awards
Sponsor: Agency for Science, Technology and Research
Location: Singapore

1974 - 1977
Medical Research Council (MRC, England) Scholar

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Patents

Title: Inhibiting Amyloid-Beta Peptide/RAGE Interaction at the Blood-Brain Barrier
U.S. Serial #: 12/223,276
Filed: Jan 26, 2007
Invented By: Rashid Deane, Benjamin Miller, Berislav Zlokovic

Publications

Journal Articles

6/2017
Lundgaard I, Lu ML, Yang E, Peng W, Mestre H, Hitomi E, Deane R, Nedergaard M. "Glymphatic clearance controls state-dependent changes in brain lactate concentration." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2017 Jun 0; 37(6):2112-2124. Epub 2016 Jan 01.

1/12/2017
Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takano T, Holtzman DM, Nedergaard M, Deane R. "Erratum to: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation." Molecular neurodegeneration.. 2017 Jan 12; 12(1):3. Epub 2017 Jan 12.

12/8/2016
Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takana T, Holtzman DM, Nedergaard M, Deane R. "Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation." Molecular neurodegeneration.. 2016 Dec 8; 11(1):74. Epub 2016 Dec 08.

Books & Chapters

1990
Chapter Title: Lead and the Brain
Book Title: Pathophysiology of the blood-brain barrier : long term consequences of barrier d
Author List: Deane, R.; Bradbury, M. W. B.
Edited By: Johansson, B. B.; Owman, C.; Widner, H.
Published By: Elsevier 1990 in New York

1987
Chapter Title: Is Pulsation Important for the Brain?
Book Title: Peptide and amino acid transport mechanisms in the central nervous system
Author List: Deane, R.; Bradbury, M. W. B.
Edited By: Rakic, L.
Published By: Macmillan 1987

1985
Chapter Title: Why is the Concentration of Glucose in CSF Less Than in Plasma?
Book Title: Carrier mediated transport of solutes from blood to tissue
Author List: Deane, R.; Segal, M. W.
Edited By: Yudilevich, D.L.; Mann, G.E.
Published By: Longman 1985 in New York

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