Yufeng Dong, Ph.D.

Yufeng Dong, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, NY 14642

Lab Information

The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.

Visit Lab Website »

Research Bio

My research focuses primarily on 1) the molecular and cellular events underlying stem cell differentiation that leads to skeletal tissue regeneration, including Notch, Wnt and TGF beta signaling; and 2) an emphasis on challenging clinical problems and translational solutions, including stem cell based cartilage, bone defect and fracture repair.

Recent Journal Articles

Showing the 5 most recent journal articles. 21 available »

2010 May
Dong Y, Jesse A, Kohn A, Gunnell L, Honjo T, Zuscik M, O'Keefe R, Hilton M. "RBPJk-dependent Notch signaling maintains and expends mesenchymal stem/progenitor cells during skeletal development". Development. 2010; 137(9): 1461-71. Link
Eliseev R, Dong Y, Sampson E, Zuscik M, Schwarz EM, O'Keefe RJ, Rosier R, Drissi H. "Runx2-mediated activation of the Bax gene increase osteosarcoma cell sensitivity to apoptosis". Oncogene. 2008; 27(25): 3605-14. Link
2007 Nov
Dong Y, Soung DY, Chang Y, Enomoto M, Paris M, Schwarz EM, O'Keefe RJ, Drissi H. "TGF-b and Wnt signaling stage-specifically regulate chondrocyte differentiation through Twist1". Molecular Endocrinology. 2007; 21(11): 2805-20. Link
Soung DY, Dong Y, Wang Y, Schwarz EM, O'Keefe RJ, Drissi H. "Runx3/AML2/Cbfa3 Regulates Early and Late Chondrocyte Differentiation". J Bone Miner Res. 2007; 8: 1260-70. Link
2006 May
Nishio Y, Dong Y, Paris M, O'Keefe RJ, Schwarz EM, Drissi H. "Runx2 mediated regulation of the zinc finger osterix/SP7 gene". Gene. 2006; 372: 62-70. Link

Current Appointments

Research Assistant Professor - Department of Orthopaedics, Center for Musculoskeletal Research (SMD) - Primary


PhD | Bone Biology | China-Shanghai 2nd Medical University College2000
MS | Tissue Engineering | China-Weifang Med Coll Shandong1997
Postdoctoral Research | Laboratory of Bone Biomechanics | Shanghai Second Medical UniversityAttended 2000 - 2001
Master | Tissue Engineering | Weifang Medical CollegeAttended 1994 - 1997