Professional Bio
Dr. Chiu received her Ph.D. from Rutgers University and was a postdoctoral fellow in immunology at Princeton University. Currently she is a Research Assistant Professor in the lab of Dr. Christopher Ritchlin where her research is centrally focused on DC-STAMP, a transmembrane protein essential for cell-cell fusion during osteoclastogenesis. Her reserach projects include investigating the role of DC-STAMP in signaling and bone healing and the regulation of cell-to-cell fusion during osteoclast differentiation.
Research Bio
Dr. Chiu is interested in delineating the molecular mechanisms underlying DC-STAMP-mediated bone homeostasis by optogenetic, musculoskeletal, and immunological approaches. Through collaborations with several principal investigators at the University of Rochester, Dr. Chiu is exploring various aspects of bone research including bone homeostasis through coordination between bone-resorbing osteoclasts (OC) and bone-synthesizing osteoblasts (OB), molecular mechanisms underlying pathological bone damages, and signaling required for the survival, differentiation, and function of OC.
2013
Chiu YG.; Ritchlin CT. "Characterization of DC-STAMP+ Cells in Human Bone Marrow". J Bone Marrow Res. 2013; 1: 127. |
2012
Chiu, Y.G.; Ritchlin, R.T. "Biomarkers to diagnose early arthritis in patients with psoriasis". Psoriasis Forum. 2012; 18(2): 48-56. |
2012
Chiu Y-H; Mensah AK; Schwarz EM; Ju Y; Takahata M; Feng C; McMahon LA; Hicks DG; Panepento B; Keng PC; Ritchlin, CT. "Regulation of Human Osteoclast Development by Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)". J Bone Miner Res. 2012; 27(1): 79-92. |
2010
Chiu Y-H.; Shao T.; Feng C.; Mensah KA.; Thullen M.; Schwarz EM.; Ritchlin CT. "CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis". Arthritis Research and Therapy. 2010; 12(1): R14. |
2009
Chiu Y-H.; Bowers WJ.; Lim ST.; Ryan DA.; Federoff HJ. "Effects of HSV amplicon transduction on murine dendritic cells". Human Gene Therapy. 2009; 20(5): 442-452. |
