YaHui Grace Chiu, Ph.D.

YaHui Grace Chiu, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 695
Rochester, NY 14642

Professional Bio

Dr. Chiu received her Ph.D. from Rutgers University and was a postdoctoral fellow in immunology at Princeton University. Currently she is a Research Assistant Professor in the lab of Dr. Christopher Ritchlin where her research is centrally focused on DC-STAMP, a transmembrane protein essential for cell-cell fusion during osteoclastogenesis. Her reserach projects include investigating the role of DC-STAMP in signaling and bone healing and the regulation of cell-to-cell fusion during osteoclast differentiation.

Research Bio

Dr. Chiu is interested in delineating the molecular mechanisms underlying DC-STAMP-mediated bone homeostasis by optogenetic, musculoskeletal, and immunological approaches. Through collaborations with several principal investigators at the University of Rochester, Dr. Chiu is exploring various aspects of bone research including bone homeostasis through coordination between bone-resorbing osteoclasts (OC) and bone-synthesizing osteoblasts (OB), molecular mechanisms underlying pathological bone damages, and signaling required for the survival, differentiation, and function of OC.

Awards & Honors (Local)

Cancer Research Institute Post-doctoral Fellowship | Cancer Research Institute 1998 - 2000
SCBA (Society of Chinese Bioscientists in America) Scholarship | Society of Chinese Bioscientists in America 1993
National Taiwan University Excellent Student Award 1989 - 1991

Recent Journal Articles

Showing the 5 most recent journal articles. 12 available »

Chiu YG.; Ritchlin CT. "Characterization of DC-STAMP+ Cells in Human Bone Marrow". J Bone Marrow Res. 2013; 1: 127.
Chiu, Y.G.; Ritchlin, R.T. "Biomarkers to diagnose early arthritis in patients with psoriasis". Psoriasis Forum. 2012; 18(2): 48-56.
Chiu Y-H; Mensah AK; Schwarz EM; Ju Y; Takahata M; Feng C; McMahon LA; Hicks DG; Panepento B; Keng PC; Ritchlin, CT. "Regulation of Human Osteoclast Development by Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)". J Bone Miner Res. 2012; 27(1): 79-92.
Chiu Y-H.; Shao T.; Feng C.; Mensah KA.; Thullen M.; Schwarz EM.; Ritchlin CT. "CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis". Arthritis Research and Therapy. 2010; 12(1): R14.
Chiu Y-H.; Bowers WJ.; Lim ST.; Ryan DA.; Federoff HJ. "Effects of HSV amplicon transduction on murine dendritic cells". Human Gene Therapy. 2009; 20(5): 442-452.

Current Appointments

Research Assistant Professor - Department of Medicine, Allergy/Immunology and Rheumatology (SMD) - Primary


PhD | Microbiology | Rutgers, Robert Wood Johnson Medical School1996
BS | Biology | Taiwan - Non-Medical School1991

Post-Doctoral Training & Residency

Post-doctoral Fellow Dept. Molecular Biology Princeton University, NJ 2000