Yahui Grace Chiu, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Locations

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 704
Rochester, NY 14642

Faculty Appointments

Research Assistant Professor - Department of Medicine , Hematology/Oncology (SMD)

Biography

Professional Background

Dr. Chiu received her Ph.D. from Rutgers University and was a postdoctoral fellow in immunology at Princeton University. Currently she is a Research Assistant Professor in the lab of Dr. Christopher Ritchlin where her research is centrally focused on DC-STAMP, a transmembrane protein essential for cell-cell fusion during osteoclastogenesis. Her reserach projects include investigating the role of DC-STAMP in signaling and bone healing and the regulation of cell-to-cell fusion during osteoclast differentiation.

Research

Dr. Chiu is interested in delineating the molecular mechanisms underlying DC-STAMP-mediated bone homeostasis by optogenetic, musculoskeletal, and immunological approaches. Through collaborations with several principal investigators at the University of Rochester, Dr. Chiu is exploring various aspects of bone research including bone homeostasis through coordination between bone-resorbing osteoclasts (OC) and bone-synthesizing osteoblasts (OB), molecular mechanisms underlying pathological bone damages, and signaling required for the survival, differentiation, and function of OC.

Credentials

Education

1991
BS | Taiwan - Non-Medical School
Biology

1996
PhD | Rutgers, Robert Wood Johnson Medical School
Microbiology

Post-doctoral Training & Residency

1997 - 2000
Post-doctoral Fellow Dept. Molecular Biology Princeton University, NJ

Awards

1998 - 2000
Cancer Research Institute Post-doctoral Fellowship
Sponsor: Cancer Research Institute

1993
SCBA (Society of Chinese Bioscientists in America) Scholarship
Sponsor: Society of Chinese Bioscientists in America

1989 - 1991
National Taiwan University Excellent Student Award

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Publications

Journal Articles

2013
Chiu YG.; Ritchlin CT. "Characterization of DC-STAMP+ Cells in Human Bone Marrow". J Bone Marrow Res. 2013; 1: 127.

2012
Chiu, Y.G.; Ritchlin, R.T. "Biomarkers to diagnose early arthritis in patients with psoriasis". Psoriasis Forum. 2012; 18(2): 48-56.

2012
Chiu Y-H; Mensah AK; Schwarz EM; Ju Y; Takahata M; Feng C; McMahon LA; Hicks DG; Panepento B; Keng PC; Ritchlin, CT. "Regulation of Human Osteoclast Development by Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)". J Bone Miner Res. 2012; 27(1): 79-92.

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