Luojing Chen, Ph.D.

Luojing Chen, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 697
Rochester, NY 14642

Fax: (585) 442-3214
Office: (585) 273-2186
Lab: (585) 275-0520

Lab Information

Dr. Chen's research interests involve B cell signaling pathways. Dr. Chen's laboratory is currentlyf ocusing on the role of PKK (a protein kinase) in lymphoma and lupus.

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The biographical information for Luojing Chen, Ph.D. is not currently available.

Awards & Honors (Local)

Award for Experimental Hemapoietic Program pilot project | University of Rochester | Rochester, NY 2003 - 2004
Massachusetts General Hospital Medical Discovery Award | Massachusetts General Hospital | Boston, MA 1998 - 1999
NIH Training Grant 1998 - 2000
Fung Endowment Fellowship | Dept of Zoology and Genetics | Iowa State Univeristy 1991


Protein Kinase C-Associated Kinase PKK is Required for NF-kB Signaling and Survival in Diffuse Large-B Cell Lymphoma Cells

United States Serial NO.: 12/672,088
Filed Date: August 6, 2008
Title: Methods of Treating B-Cell Cancers
Invented by: Luojing Chen, Jiyong Zhao

Recent Journal Articles

Showing the 5 most recent journal articles. 19 available »

2016 Apr
Chen L, Oleksyn D, Pulvino M, Sanz I, Ryan D, Ryan C, Lin CS, Poligone B, Pentland AP, Ritchlin C, Zhao J. "A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells." Immunology letters. 2016 Apr; 172:67-78. Epub 2016 Feb 26.
2015 Jun 20
Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, Spence S, Balakrishnan V, Jordan C, Poligone B, Casulo C, Burack R, Shapiro JL, Bernstein S, Friedberg JW, Deshaies RJ, Land H, Zhao J. "Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline." Oncotarget. 2015 Jun 20; 6(17):14796-813.
2015 Mar
Poligone B, Gilmore ES, Alexander C, Oleksyn D, Gillespie K, Zhao J, Ibrahim S, Pentland AP, Brown M, Chen L. "PKK suppresses tumor growth and is decreased in squamous cell carcinoma of the skin." The Journal of investigative dermatology. 2015 Mar; 135(3):869-76. Epub 2014 Oct 06.
2014 Oct
Kim SW, Schifano M, Oleksyn D, Jordan CT, Ryan D, Insel R, Zhao J, Chen L. "Protein kinase C-associated kinase regulates NF-?B activation through inducing IKK activation." Int J Oncol. 2014; 45(4):1707-14.
2013 Aug
Poligone B, Hayden MS, Chen L, Pentland AP, Jimi E, Ghosh S. "A role for NF-?B activity in skin hyperplasia and the development of keratoacanthomata in mice". PLoS One. 2013; 9;8(8):e71887.

Current Appointments

Research Assistant Professor - Department of Dermatology (SMD) - Primary


PhD | Genetics | Iowa State University1992
MS | Microbiology | China-Wuhan University1985
BS | Biology | China-Wuhan University1982

Post-Doctoral Training & Residency

Postdoctoral Fellow Signaling Transduction Lab Massachusetts General Hospital Harvard Medical School Charlestown, MA 2000
Postdoctoral Fellow Molecular Biology Massachusetts General Hospital Harvard Medical School Boston, MA 1996
Postdoctoral Fellow Genetics Department Iowa State University Ames, IA. 1995