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Michael W. Becker, M.D.

Cancer

Publications

Showing all 43 journal articles & 0 books available

Journal Articles

3/2017
Hunter BD, Herr M, Meacham PJ, Barlaskar F, Evans AG, Burack WR, Liesveld JL, Becker MW, Milner LA, Constine LS, Dhakal S, Barr PM, Friedberg JW, Casulo C. "Late Relapses After High-dose Chemotherapy and Autologous Stem Cell Transplantation in Patients With Diffuse Large B-cell Lymphoma in the Rituximab Era." Clinical lymphoma, myeloma & leukemia.. 2017 Mar 0; 17(3):145-151. Epub 2016 Nov 23.

11/2016
Reid RM, Baran A, Friedberg JW, Phillips GL, Liesveld JL, Becker MW, Wedow L, Barr PM, Milner LA. "Outpatient administration of BEAM conditioning prior to autologous stem cell transplantation for lymphoma is safe, feasible, and cost-effective." Cancer medicine. 2016 Nov 0; 5(11):3059-3067. Epub 2016 Oct 03.

10/1/2016
Dhakal S, Bates JE, Casulo C, Friedberg JW, Becker MW, Liesveld JL, Constine LS. "Patterns and Timing of Failure for Diffuse Large B-Cell Lymphoma After Initial Therapy in a Cohort Who Underwent Autologous Bone Marrow Transplantation for Relapse." International journal of radiation oncology, biology, physics.. 2016 Oct 1; 96(2):372-8. Epub 2016 May 27.

9/29/2016
Ho TC, LaMere M, Stevens BM, Ashton JM, Myers JR, O'Dwyer KM, Liesveld JL, Mendler JH, Guzman M, Morrissette JD, Zhao J, Wang ES, Wetzler M, Jordan CT, Becker MW. "Evolution of acute myelogenous leukemia stem cell properties after treatment and progression." Blood.. 2016 Sep 29; 128(13):1671-8. Epub 2016 Jul 15.

2/4/2016
Balderman SR, Li AJ, Hoffman CM, Frisch BJ, Goodman AN, LaMere MW, Georger MA, Evans AG, Liesveld JL, Becker MW, Calvi LM. "Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome." Blood.. 2016 Feb 4; 127(5):616-25. Epub 2015 Dec 04.

12/15/2015
Zong H, Gozman A, Caldas-Lopes E, Taldone T, Sturgill E, Brennan S, Ochiana SO, Gomes-DaGama EM, Sen S, Rodina A, Koren J, Becker MW, Rudin CM, Melnick A, Levine RL, Roboz GJ, Nimer SD, Chiosis G, Guzman ML. "A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species." Cell reports. 2015 Dec 15; 13(10):2159-73. Epub 2015 Nov 25.

2015
Sivagnanalingam U, Balys M, Eberhardt A, Wang N, Myers JR, Ashton JM, Becker MW, Calvi LM, Mendler JH. "Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia." PloS one. 2015 10(7):e0132375. Epub 2015 Jul 15.

8/2014
Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. "Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia." Molecular cancer therapeutics.. 2014 Aug 0; 13(8):1979-90. Epub 2014 Jun 16.

7/3/2014
Zahreddine HA, Culjkovic-Kraljacic B, Assouline S, Gendron P, Romeo AA, Morris SJ, Cormack G, Jaquith JB, Cerchietti L, Cocolakis E, Amri A, Bergeron J, Leber B, Becker MW, Pei S, Jordan CT, Miller WH, Borden KL. "The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation." Nature.. 2014 Jul 3; 511(7507):90-3. Epub 2014 May 28.

2014
Brown JT, Burack WR, Becker MW, Vlad-Vonica R, Nadasdy T, Bennett JM, Mendler JH. "Extracellular crystals in plasma cell myeloma." Leukemia research reports.. 2014 3(2):49-50. Epub 2014 Jun 18.

12/2013
Liesveld JL, O'Dwyer K, Walker A, Becker MW, Ifthikharuddin JJ, Mulford D, Chen R, Bechelli J, Rosell K, Minhajuddin M, Jordan CT, Phillips GL. "A phase I study of decitabine and rapamycin in relapsed/refractory AML." Leukemia research.. 2013 Dec 0; 37(12):1622-7. Epub 2013 Sep 08.

11/22/2013
Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT. "Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells." The Journal of biological chemistry.. 2013 Nov 22; 288(47):33542-58. Epub 2013 Oct 02.

11/1/2013
Ho TC, Becker MW. "Defining patient-specific risk in acute myeloid leukemia." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2013 Nov 1; 31(31):3857-9. Epub 2013 Sep 23.

9/2013
Sen S, Hassane DC, Corbett C, Becker MW, Jordan CT, Guzman ML. "Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity." Experimental hematology.. 2013 Sep 0; 41(9):799-807.e4. Epub 2013 May 06.

9/2013
Hashmi S, Oliva JL, Liesveld JL, Phillips GL, Milner L, Becker MW. "The hematopoietic cell transplantation specific comorbidity index and survival after extracorporeal photopheresis, pentostatin, and reduced dose total body irradiation conditioning prior to allogeneic stem cell transplantation." Leukemia research.. 2013 Sep 0; 37(9):1052-6. Epub 2013 Jul 03.

5/2013
Liesveld J, Pawlowski J, Chen R, Hyrien O, Debolt J, Becker M, Phillips G, Chen Y. "Clinical factors affecting engraftment and transfusion needs in SCT: a single-center retrospective analysis." Bone marrow transplantation.. 2013 May 0; 48(5):691-7. Epub 2012 Oct 22.

3/7/2013
Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, Minhajuddin M, Ashton JM, Pei S, Grose V, O'Dwyer KM, Liesveld JL, Brookes PS, Becker MW, Jordan CT. "BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells." Cell stem cell.. 2013 Mar 7; 12(3):329-41. Epub 2013 Jan 17.

7/2012
Reid R, Bennett JM, Becker M, Chen Y, Milner L, Phillips Ii GL, Liesveld J. "Use of eltrombopag, a thrombopoietin receptor agonist, in post-transplantation thrombocytopenia." American journal of hematology.. 2012 Jul 0; 87(7):743-5. Epub 2012 May 10.

5/2012
Ban-Hoefen M, Kelly JL, Bernstein SH, Liesveld J, Constine L, Becker M, Milner L, Phillips G, Friedberg JW. "High-dose therapy and autologous stem cell transplant for transformed non-Hodgkin lymphoma in the rituximab era." Leukemia & lymphoma.. 2012 May 0; 53(5):830-5. Epub 2011 Dec 06.

1/12/2012
Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. "Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia." Blood.. 2012 Jan 12; 119(2):540-50. Epub 2011 Sep 28.

2012
Keller, SF; Kelly, JL; Sensenig, E; Andreozzi, J; Oliva, J; Rich, L; Constine, L; Becker, M; Phillips, G; Liesveld, J; Fisher, RI; Bernstein, SH; Friedberg, JW. "Late Relapses following High-Dose Autologous Stem Cell Transplantation (HD-ASCT) for Hodgkin's Lymphoma (HL) in the ABVD Therapeutic Era." Biol Blood Marrow Transplant. 2012; 18(4): 640-7.

9/2/2011
Becker MW, Jordan CT. "Leukemia stemness signatures step toward the clinic." Cell stem cell.. 2011 Sep 2; 9(3):185-6.

8/2011
Milner LA, Becker MW, Bernstein SH, Bruckner L, Friedberg JW, Holland GA, Ifthikharuddin JJ, Liesveld JL, Mathes EJ, Menchel HL, Mullen CA, Sasson T, Phillips GL. "Intra-arterial methylprednisolone for the management of steroid-refractory acute gastrointestinal and hepatic graft versus host disease." American journal of hematology.. 2011 Aug 0; 86(8):712-4. Epub 2011 May 31.

7/2011
Phillips GL, Bernstein SH, Liesveld JL, Abboud CN, Becker MW, Constine LS, Ifthikharuddin JJ, Loughner JE, Milner LA, Vesole DH, Friedberg JW. "A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection." Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2011 Jul 0; 17(7):1033-42. Epub 2010 Nov 11.

3/2011
Becker MW, Jordan CT. "Leukemia stem cells in 2010: current understanding and future directions." Blood reviews.. 2011 Mar 0; 25(2):75-81. Epub 2011 Jan 08.

6/10/2010
Fu CT, Zhu KY, Mi JQ, Liu YF, Murray ST, Fu YF, Ren CG, Dong ZW, Liu YJ, Dong M, Jin Y, Chen Y, Deng M, Zhang W, Chen B, Breslin P, Chen SJ, Chen Z, Becker MW, Zhu J, Zhang JW, Liu TX. "An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 axis controls myeloid development and transformation." Blood.. 2010 Jun 10; 115(23):4715-24. Epub 2010 Apr 06.

3/3/2009
Majeti R, Becker MW, Tian Q, Lee TL, Yan X, Liu R, Chiang JH, Hood L, Clarke MF, Weissman IL. "Dysregulated gene expression networks in human acute myelogenous leukemia stem cells." Proceedings of the National Academy of Sciences of the United States of America.. 2009 Mar 3; 106(9):3396-401. Epub 2009 Feb 13.

7/2008
Laughlin TS, Becker MW, Liesveld JL, Mulford DA, Abboud CN, Brown P, Rothberg PG. "Rapid method for detection of mutations in the nucleophosmin gene in acute myeloid leukemia." The Journal of molecular diagnostics : JMD.. 2008 Jul 0; 10(4):338-45. Epub 2008 Jun 13.

5/8/2008
Akala OO, Park IK, Qian D, Pihalja M, Becker MW, Clarke MF. "Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors." Nature.. 2008 May 8; 453(7192):228-32. Epub 2008 Apr 16.

2008
Walker, AR; Komrokji, RS; Ifthikharuddin, J; Messina, P; Mulford, D; Becker, M; Friedberg, J; Oliva, J; Phillips, G; Liesveld, JL; Abboud, C. "Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor (G-CSF) (CLAG Regimen) and simultaneous escalating doses of imatinib mesylate (Gleevec) in relapsed/refractory AML." Leuk Res. 2008; : 1830-6.

12/15/2007
Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. "An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells." Blood.. 2007 Dec 15; 110(13):4427-35. Epub 2007 Sep 05.

1/2007
Liu TX, Becker MW, Jelinek J, Wu WS, Deng M, Mikhalkevich N, Hsu K, Bloomfield CD, Stone RM, DeAngelo DJ, Galinsky IA, Issa JP, Clarke MF, Look AT. "Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation." Nature medicine.. 2007 Jan 0; 13(1):78-83. Epub 2006 Dec 10.

7/2006
Clarke MF, Becker MW. "Stem cells: the real culprits in cancer?" Scientific American.. 2006 Jul 0; 295(1):52-9.

2005
Uberti, JP; Ayash, L; Ratanatharathorn,V;Silver, S; Reynolds, C; Becker, M; Reddy, P; Cooke, KR; Yanik, G; Whitfield, J; Jones, D; Hutchinson, R; Braun, T; Ferrara, JL; Levine, JE. "Pilot Trial on the Use of Etanercept and Methylprednisolone as Primary Treatment for Acute Graft-versus-Host Disease." Biol Blood Marrow Transplant. 2005; 11(9): 680-7.

2/2004
Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF. "Therapeutic implications of cancer stem cells." Current opinion in genetics & development.. 2004 Feb 0; 14(1):43-7.

5/2003
Park I, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL, Morrison IL, and Clarke MF. "Bmil is required for adult hematopoietic stem cell self renewel". Nature. 2003; 43: 302-5.

2003
Ratanatharathorn V, Ayash L, Reynolds C, Silver S, Reddy P, Becker MW, Ferrara JL, Uberti JP. "Treatment of chronic graft-versus-host disease with anti-Cd20 chimeric monoclonal antibody". Biology Blood Marrow Transplant. 2003; 9(8): 505-11.

10/2002
Becker MW, Clarke MF. "SLUGging away at cell death." Cancer cell.. 2002 Oct 0; 2(4):249-51.

11/1994
Ali S, Becker MW, Davis MG, Dorn GW. "Dissociation of vasoconstrictor-stimulated basic fibroblast growth factor expression from hypertrophic growth in cultured vascular smooth muscle cells. Relevant roles of protein kinase C." Circulation research.. 1994 Nov 0; 75(5):836-43.

8/15/1993
Ali S, Davis MG, Becker MW, Dorn GW. "Thromboxane A2 stimulates vascular smooth muscle hypertrophy by up-regulating the synthesis and release of endogenous basic fibroblast growth factor." The Journal of biological chemistry.. 1993 Aug 15; 268(23):17397-403.

4/1993
Dorn GW, Becker MW. "Thromboxane A2 stimulated signal transduction in vascular smooth muscle." The Journal of pharmacology and experimental therapeutics.. 1993 Apr 0; 265(1):447-56.

12/5/1992
Dorn GW, Becker MW, Davis MG. "Dissociation of the contractile and hypertrophic effects of vasoconstrictor prostanoids in vascular smooth muscle." The Journal of biological chemistry.. 1992 Dec 5; 267(34):24897-905.

4/1992
Dorn GW, Becker MW. "Growth factors downregulate vascular smooth muscle thromboxane receptors independent of cell growth." The American journal of physiology.. 1992 Apr 0; 262(4 Pt 1):C927-33.