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Xin Lin, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Biography

Research

My research focuses on investigating gene therapy approaches and underlying mechanisms for protection and treatment for lung diseases emphasizing on acute lung injury/acute respiratory distress syndrome or pulmonary fibrosis.

Gene therapy is a promising approach to provide protection and treatment of acute and chronic lung diseases by restoring lung function. Our laboratory has developed a technique, electroporation, to efficiently deliver naked DNA to various tissues, including the living lung, with high-level gene expression and without damage. Our goal is to lead to a safe and effective approach to overexpress desired gene(s) in the injured lung to regulate lung function. It will provide evidence to move gene therapy toward clinical application.

Credentials

Faculty Appointments

Education

2001
MS | China-Lanzhou University
Pathogenic Biology

2004
PhD | China-Lanzhou University
Biochemistry and Molecular Biology

Awards

2013
Abstract Scholarship Award
Sponsor: ATS International Conference in Philadelphia, PA

2012
Travel Award
Sponsor: Pittsburgh International Lung Conference, Pittsburgh, PA

2011 - 2013
T32 Training Grant (HL66988)
Sponsor: American National Institutes of Health (NIH)

2011
Best Postdoctoral Poster Award
Sponsor: 3rd Annual Lung Research & Trainee Day, University of Rochester
Location: Rochester, NY

2005
Postdoctoral Fellowship
Sponsor: China Postdoctoral Science Foundation

2004
Zhong-He Award
Sponsor: 8th Chinese International Peptide Symposium
Location: Kunming, China

2003
Qiushi Award
Location: Hong Kong, China

2003
The 7th Fudan University Tan Jiazhen Prize Life Sciences Jiuyuan Award
Location: China

2003
Science and Technology Award of Graduate Students
Sponsor: Lanzhou University, China

2002 - 2003
Excellent Graduate Student Award
Sponsor: Lanzhou University, China

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Publications

Journal Articles

1/2013
Roy S, Habashi N, Sadowitz B, Andrews P, Ge L, Wang G, Roy P, Ghosh A, Kuhn M, Satalin J, Gatto LA, Lin X, Dean DA, Vodovotz Y, Nieman G. "Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury." Shock.. 2013 Jan 0; 39(1):28-38.

8/2012
Roy S, Sadowitz B, Andrews P, Gatto LA, Marx W, Ge L, Wang G, Lin X, Dean DA, Kuhn M, Ghosh A, Satalin J, Snyder K, Vodovotz Y, Nieman G, Habashi N. "Early stabilizing alveolar ventilation prevents acute respiratory distress syndrome: a novel timing-based ventilatory intervention to avert lung injury." The journal of trauma and acute care surgery.. 2012 Aug 0; 73(2):391-400.

7/2011
Lin X, Dean DA. "Gene therapy for ALI/ARDS." Critical care clinics.. 2011 Jul 0; 27(3):705-18.

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