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Michael F. Swartz, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-2735

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Biography

Professional Background

Michael Swartz started his medical career as a physician's assistant in the division of cardiac surgery at SUNY Upstate in Syracuse, New York. While at SUNY Upstate, Michael completed a Master's of Science in physiology in 2007, and PhD in pharmacology in 2009. Following completion of his graduate work, Michael joined the URMC as both a physician's assistant on the cardiac surgery service and a post-doctoral research fellow working with Dr. George Alfieris. Following completion of his post-doctoral research fellowship he was appointed as an assistant professor of surgery at URMC in 2013.

Research

Despite surgical ingenuity to palliate the 1000 infants born annually in the United States with single ventricle (SV) physiology, the predicted life expectancy for these patients remains less than three decades without cardiac transplantation. Shortly after birth, infants undergo the first in a series of operations which ultimately diverts systemic venous return away from the heart, directly into the pulmonary vasculature. Although short and midterm results of this palliation are acceptable, the majority of patients succumb to heart failure. Cardiac transplantation is the optimal treatment; however, due to limited organ supply and an absence of circulatory support strategies, nearly 25% of failing SV patients die while awaiting cardiac transplant.
We have developed a survival, single ventricle, large animal model that we are currently using to test different strategies for mechanical circulatory support. These strategies developed at the URMC and from other vendors, may provide further options for single ventricle patients while awaiting transplant.

Credentials

Faculty Appointments

Specialties

  • Physician Assistant - NCCPA

Education

2009
PhD | SUNY Upstate Medical University
Pharmacology

2007
MHS | University of Nebraska
Physician Assistant

2007
MS | SUNY Upstate Medical Unviersity
Physiology

2001
BS | D'Youville College Buffalo
Physician Assistant Studies

Awards

2011
Best Clinical Presentation
Sponsor: Cardiac Electrophysiology Society
Location: Orlando, FL

2009
Allied Professional Award
Sponsor: Heart Rhythm Society
Location: Boston, MA

2007
Professional Development Award
Sponsor: United University Professions

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Publications

Journal Articles

4/5/2017
Tchantchaleishvili V, Wood KL, Carlson LA, Barrus B, Swartz MF, Vidula H, Lehoux JM, Todd Massey H, Chen L. "Temporary mechanical circulatory support after orthotopic heart transplantation: a single-centre experience." Interactive cardiovascular and thoracic surgery.. 2017 Apr 5; Epub 2017 Apr 05.

2/2017
Swartz MF, DiVincenti L, Smith K, Westcott R, Belmont K, Harris W, Gensini F, Alfieris GM. "A modified LVAD technique to augment caval and pulmonary arterial blood flow in the "failing Fontan" circulation." Journal of cardiac surgery.. 2017 Feb 0; 32(2):126-132. Epub 2017 Jan 09.

1/2/2017
Freires IA, Avilés-Reyes A, Kitten T, Simpson-Haidaris PJ, Swartz M, Knight PA, Rosalen PL, Lemos JA, Abranches J. "Heterologous expression of Streptococcus mutans Cnm in Lactococcus lactis promotes intracellular invasion, adhesion to human cardiac tissues and virulence." Virulence.. 2017 Jan 2; 8(1):18-29. Epub 2016 Jun 03.

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