Minsoo Kim, Ph.D.

Minsoo Kim, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 609
Rochester, NY 14642

Administrative: (585) 273-1400
Lab: (585) 273-1435
Fax: (585) 273-2452
Office: (585) 276-3917

Journal Articles

Showing all 62 journal articles available.

2016 Jul
Capece T, Kim M. "The Role of Lymphatic Niches in T Cell Differentiation." Molecules and cells. 2016 Jul; 39(7):515-23. Epub 2016 Jun 16.
2016 Jun 1
Park S, Kim SJ, Yu D, Pena-Llopis S, Gao J, Park JS, Chen B, Norris J, Wang X, Chen M, Kim M, Yong J, Wardak Z, Choe K, Story M, Starr T, Cheong JH, Hwang TH. "An integrative somatic mutation analysis to identify pathways linked with survival outcomes across 19 cancer types." Bioinformatics. 2016 Jun 1; 32(11):1643-51. Epub 2015 Dec 03.
2016 Feb 23
Surve CR, To JY, Malik S, Kim M, Smrcka AV. "Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits G?i-GTP and G??." Science signaling. 2016 Feb 23; 9(416):ra22. Epub 2016 Feb 23.
Nedelkovska H, Rosenberg AF, Hilchey SP, Hyrien O, Burack WR, Quataert SA, Baker CM, Azadniv M, Welle SL, Ansell SM, Kim M, Bernstein SH. "Follicular Lymphoma Tregs Have a Distinct Transcription Profile Impacting Their Migration and Retention in the Malignant Lymph Node." PloS one. 2016 11(5):e0155347. Epub 2016 May 26.
2015 Nov
Lim K, Hyun YM, Lambert-Emo K, Topham DJ, Kim M. "Visualization of integrin Mac-1 in vivo." Journal of immunological methods. 2015 Nov; 426:120-7. Epub 2015 Sep 02.
2015 Sep 22
Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. "Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes." Oncotarget. 2015 Sep 22; 6(28):25240-51.
2015 Sep 4
Lim K, Hyun YM, Lambert-Emo K, Capece T, Bae S, Miller R, Topham DJ, Kim M. "Neutrophil trails guide influenza-specific CD8? T cells in the airways." Science. 2015 Sep 4; 349(6252):aaa4352.
2015 Apr 13
Na BR, Kim HR, Piragyte I, Oh HM, Kwon MS, Akber U, Lee HS, Park DS, Song WK, Park ZY, Im SH, Rho MC, Hyun YM, Kim M, Jun CD. "TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse." The Journal of cell biology. 2015 Apr 13; 209(1):143-62.
Haynes-Gimore N, Banach M, Brown E, Dawes R, Edholm ES, Kim M, Robert J. "Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration." Developmental biology. 2015 408(2):205-12. Epub 2015 Jan 17.
Lerman YV, Kim M. "Neutrophil migration under normal and sepsis conditions." Cardiovascular & hematological disorders drug targets. 2015 15(1):19-28.
2014 Nov 12
Kim J, Lim J, Kim M, Lee HS, Kim D, Jun Y. "Fabrication of carbon-coated silicon nanowires and their application in dye-sensitized solar cells." ACS applied materials & interfaces. 2014 Nov 12; 6(21):18788-94. Epub 2014 Oct 24.
2014 Jul
Zhong R, Kim J, Kim HS, Kim M, Lum L, Levine B, Xiao G, White MA, Xie Y. "Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens." Nucleic acids research. 2014 Jul; 42(13):8214-22. Epub 2014 Jun 27.
2014 Jun 15
Stevenson C, de la Rosa G, Anderson CS, Murphy PS, Capece T, Kim M, Elliott MR. "Essential role of Elmo1 in Dock2-dependent lymphocyte migration." The Journal of immunology : official journal of the American Association of Immunologists. 2014 Jun 15; 192(12):6062-70. Epub 2014 May 12.
2014 Jun
Baik SH, Cha MY, Hyun YM, Cho H, Hamza B, Kim DK, Han SH, Choi H, Kim KH, Moon M, Lee J, Kim M, Irimia D, Mook-Jung I. "Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model." Neurobiology of aging. 2014 Jun; 35(6):1286-92. Epub 2014 Jan 08.
2014 Apr 29
Xu Y, Hyun YM, Lim K, Lee H, Cummings RJ, Gerber SA, Bae S, Cho TY, Lord EM, Kim M. "Optogenetic control of chemokine receptor signal and T-cell migration." Proceedings of the National Academy of Sciences of the United States of America. 2014 Apr 29; 111(17):6371-6. Epub 2014 Apr 14.
2014 Apr
Polesskaya O, Wong C, Lebron L, Chamberlain JM, Gelbard HA, Goodfellow V, Kim M, Daiss JL, Dewhurst S. "MLK3 regulates fMLP-stimulated neutrophil motility." Molecular immunology. 2014 Apr; 58(2):214-22. Epub 2014 Jan 03.
Lerman YV, Lim K, Hyun YM, Falkner KL, Yang H, Pietropaoli AP, Sonnenberg A, Sarangi PP, Kim M. "Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin ?3?1-dependent." Blood. 2014 124(24):3515-23. Epub 2014 Oct 02.
Kim M, Woo SK, Yu JW, Lee YJ, Kim KM, Kang JH, Eom KD, Nahm SS. "Effect of Harderian adenectomy on the statistical analyses of mouse brain imaging using positron emission tomography." Journal of veterinary science. 2014 15(1):157-61. Epub 2013 Jun 30.
Yu JE, Kim M, Lee JH, Chang BJ, Song CS, Nahm SS. "Neonatal influenza infection causes pathological changes in the mouse brain." Veterinary research. 2014 45:63. Epub 2014 Jun 10.
Knowlden SA, Capece T, Popovic M, Chapman TJ, Rezaee F, Kim M, Georas SN. "Regulation of T cell motility in vitro and in vivo by LPA and LPA2." PloS one. 2014 9(7):e101655. Epub 2014 Jul 08.
Kim M, Otsubo R, Morikawa H, Nishide A, Takagi K, Sasakawa C, Mizushima T. "Bacterial effectors and their functions in the ubiquitin-proteasome system: insight from the modes of substrate recognition." Cells. 2014 3(3):848-64. Epub 2014 Aug 18.
2013 Nov 18
Ye F, Petrich BG, Anekal P, Lefort CT, Kasirer-Friede A, Shattil SJ, Ruppert R, Moser M, Fässler R, Ginsberg MH. "The mechanism of kindlin-mediated activation of integrin ?IIb?3." Current biology : CB. 2013 Nov 18; 23(22):2288-95. Epub 2013 Nov 07.
2013 Sep
Overstreet MG, Gaylo A, Angermann BR, Hughson A, Hyun YM, Lambert K, Acharya M, Billroth-Maclurg AC, Rosenberg AF, Topham DJ, Yagita H, Kim M, Lacy-Hulbert A, Meier-Schellersheim M, Fowell DJ. "Inflammation-induced interstitial migration of effector CD4? T cells is dependent on integrin ?V." Nature immunology. 2013 Sep; 14(9):949-58. Epub 2013 Aug 11.
2013 Aug 9
Nishide A, Kim M, Takagi K, Himeno A, Sanada T, Sasakawa C, Mizushima T. "Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI." Journal of molecular biology. 2013 Aug 9; 425(15):2623-31. Epub 2013 Mar 27.
2013 Aug
Dong J, He Y, Kim M, Shin K. "Effect of creep stress on the microstructure of 9-12% Cr steel for rotor materials." Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 2013 Aug; 19 Suppl 5:95-8.
2013 May
Kim K, Kam D, Kim Y, Kim S, Kim M, Kim HS. "Electrochemical studies of molybdate-doped LiFePO4 as a cathode material in Li-ion batteries." Journal of nanoscience and nanotechnology. 2013 May; 13(5):3383-6.
2013 Mar
Ball CJ, Reiffel AJ, Chintalapani S, Kim M, Spector JA, King MR. "Hydrogen sulfide reduces neutrophil recruitment in hind-limb ischemia-reperfusion injury in an L-selectin and ADAM-17-dependent manner." Plastic and reconstructive surgery. 2013 Mar; 131(3):487-97.
2013 Feb
Yu C, Xu L, Chen LF, Guan YJ, Kim M, Biffl WL, Eugene Chin Y. "PRBC-derived plasma induces non-muscle myosin type IIA-mediated neutrophil migration and morphologic change." Immunopharmacology and immunotoxicology. 2013 Feb; 35(1):71-9. Epub 2012 Oct 19.
2012 Aug
Sarangi PP, Hyun YM, Lerman YV, Pietropaoli AP, Kim M. "Role of ?1 integrin in tissue homing of neutrophils during sepsis." Shock. 2012 Aug; 38(3):281-7.
2012 Aug
Kim M, Lee U, Small I, des Francs-Small CC, Vierling E. "Mutations in an Arabidopsis mitochondrial transcription termination factor-related protein enhance thermotolerance in the absence of the major molecular chaperone HSP101." The Plant cell. 2012 Aug; 24(8):3349-65. Epub 2012 Aug 31.
2012 Jul 2
Hyun YM, Sumagin R, Sarangi PP, Lomakina E, Overstreet MG, Baker CM, Fowell DJ, Waugh RE, Sarelius IH, Kim M. "Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels." The Journal of experimental medicine. 2012 Jul 2; 209(7):1349-62. Epub 2012 Jun 18.
2012 Jun 26
Baker CM, Comrie WA, Hyun YM, Chung HL, Fedorchuk CA, Lim K, Brakebusch C, McGrath JL, Waugh RE, Meier-Schellersheim M, Kim M. "Opposing roles for RhoH GTPase during T-cell migration and activation." Proceedings of the National Academy of Sciences of the United States of America. 2012 Jun 26; 109(26):10474-9. Epub 2012 Jun 11.
2012 Jan 27
O'Brien XM, Heflin KE, Lavigne LM, Yu K, Kim M, Salomon AR, Reichner JS. "Lectin site ligation of CR3 induces conformational changes and signaling." The Journal of biological chemistry. 2012 Jan 27; 287(5):3337-48. Epub 2011 Dec 09.
Lefort CT, Hyun YM, Kim M. "Monitoring integrin activation by fluorescence resonance energy transfer." Methods in molecular biology. 2012 757:205-14.
2011 Aug 1
Guan YJ, Zhang Z, Yu C, Ma L, Hu W, Xu L, Gao JS, Chung CS, Wang L, Yang ZF, Fast LD, Chung AS, Kim M, Ayala A, Zhuang S, Zheng S, Chin YE. "Phospho-SXXE/D motif mediated TNF receptor 1-TRADD death domain complex formation for T cell activation and migration." The Journal of immunology : official journal of the American Association of Immunologists. 2011 Aug 1; 187(3):1289-97. Epub 2011 Jul 01.
Sanchez-Lockhart M, Kim M, Miller J. "Cutting edge: A role for inside-out signaling in TCR regulation of CD28 ligand binding." The Journal of immunology : official journal of the American Association of Immunologists. 2011 187(11):5515-9. Epub 2011 Nov 07.
2010 Nov 9
Ma L, Gao JS, Guan Y, Shi X, Zhang H, Ayrapetov MK, Zhang Z, Xu L, Hyun YM, Kim M, Zhuang S, Chin YE. "Acetylation modulates prolactin receptor dimerization." Proceedings of the National Academy of Sciences of the United States of America. 2010 Nov 9; 107(45):19314-9. Epub 2010 Oct 20.
2010 Apr 6
Hu X, Kang S, Lefort C, Kim M, Jin MM. "Combinatorial libraries against libraries for selecting neoepitope activation-specific antibodies." Proceedings of the National Academy of Sciences of the United States of America. 2010 Apr 6; 107(14):6252-7. Epub 2010 Mar 22.
2010 Mar
Sarangi PP, Lee HW, Kim M. "Activated protein C action in inflammation." British journal of haematology. 2010 Mar; 148(6):817-33. Epub 2009 Dec 08.
Lefort CT, Kim M. "Human T lymphocyte isolation, culture and analysis of migration in vitro." Journal of visualized experiments : JoVE. 2010 (40)Epub 2010 Jun 01.
2009 Nov 15
Lefort CT, Hyun YM, Schultz JB, Law FY, Waugh RE, Knauf PA, Kim M. "Outside-in signal transmission by conformational changes in integrin Mac-1." The Journal of immunology : official journal of the American Association of Immunologists. 2009 Nov 15; 183(10):6460-8. Epub 2009 Oct 28.
2009 Jul 1
Hyun YM, Chung HL, McGrath JL, Waugh RE, Kim M. "Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1." The Journal of immunology : official journal of the American Association of Immunologists. 2009 Jul 1; 183(1):359-69.
2009 Jul
Quinn JA, Graeber CT, Frackelton AR, Kim M, Schwarzbauer JE, Filardo EJ. "Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30." Molecular endocrinology. 2009 Jul; 23(7):1052-64. Epub 2009 Apr 02.
2009 Apr 23
Elphick GF, Sarangi PP, Hyun YM, Hollenbaugh JA, Ayala A, Biffl WL, Chung HL, Rezaie AR, McGrath JL, Topham DJ, Reichner JS, Kim M. "Recombinant human activated protein C inhibits integrin-mediated neutrophil migration." Blood. 2009 Apr 23; 113(17):4078-85. Epub 2009 Feb 24.
Hyun YM, Lefort CT, Kim M. "Leukocyte integrins and their ligand interactions." Immunologic research. 2009 45(2-3):195-208. Epub 2009 Jan 29.
2008 Nov
Kaba NK, Schultz J, Law FY, Lefort CT, Martel-Gallegos G, Kim M, Waugh RE, Arreola J, Knauf PA. "Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils." American journal of physiology. Cell physiology. 2008 Nov; 295(5):C1454-63. Epub 2008 Oct 01.
2008 Apr
Shaw SK, Owolabi SA, Bagley J, Morin N, Cheng E, LeBlanc BW, Kim M, Harty P, Waxman SG, Saab CY. "Activated polymorphonuclear cells promote injury and excitability of dorsal root ganglia neurons." Experimental neurology. 2008 Apr; 210(2):286-94. Epub 2007 Dec 04.
2008 Jan 21
Morin NA, Oakes PW, Hyun YM, Lee D, Chin YE, Chin EY, King MR, Springer TA, Shimaoka M, Tang JX, Reichner JS, Kim M. "Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration." The Journal of experimental medicine. 2008 Jan 21; 205(1):195-205. Epub 2008 Jan 14.
2007 Oct 1
Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. "Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling." Blood. 2007 Oct 1; 110(7):2475-83. Epub 2007 Jul 05.
2007 Jun 1
Lavigne LM, O'Brien XM, Kim M, Janowski JW, Albina JE, Reichner JS. "Integrin engagement mediates the human polymorphonuclear leukocyte response to a fungal pathogen-associated molecular pattern." The Journal of immunology : official journal of the American Association of Immunologists. 2007 Jun 1; 178(11):7276-82.
2007 Apr
Kim M, Christofi FL, Xue J, Robinson JM, Cooke HJ. "Mechanically evoked 5-hydroxytryptamine release is mediated by caveolin-associated cholesterol rich membrane domains." Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2007 Apr; 19(4):309-17.
2007 Mar
Morin N, Owolabi SA, Harty MW, Papa EF, Tracy TF, Shaw SK, Kim M, Saab CY. "Neutrophils invade lumbar dorsal root ganglia after chronic constriction injury of the sciatic nerve." Journal of neuroimmunology. 2007 Mar; 184(1-2):164-71. Epub 2007 Feb 01.
2006 Sep 19
Shimaoka M, Kim M, Cohen EH, Yang W, Astrof N, Peer D, Salas A, Ferrand A, Springer TA. "AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes." Proceedings of the National Academy of Sciences of the United States of America. 2006 Sep 19; 103(38):13991-6. Epub 2006 Sep 08.
2006 Aug 29
Chen J, Yang W, Kim M, Carman CV, Springer TA. "Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2." Proceedings of the National Academy of Sciences of the United States of America. 2006 Aug 29; 103(35):13062-7. Epub 2006 Aug 18.
2006 Apr 21
Salas A, Shimaoka M, Phan U, Kim M, Springer TA. "Transition from rolling to firm adhesion can be mimicked by extension of integrin alphaLbeta2 in an intermediate affinity state." The Journal of biological chemistry. 2006 Apr 21; 281(16):10876-82. Epub 2006 Feb 27.
Yang W, Carman CV, Kim M, Salas A, Shimaoka M, Springer TA. "A small molecule agonist of an integrin, alphaLbeta2." The Journal of biological chemistry. 2006 281(49):37904-12. Epub 2006 Oct 05.
2004 Jul
Christofi FL, Kim M, Wunderlich JE, Xue J, Suntres Z, Cardounel A, Javed NH, Yu JG, Grants I, Cooke HJ. "Endogenous adenosine differentially modulates 5-hydroxytryptamine release from a human enterochromaffin cell model." Gastroenterology. 2004 Jul; 127(1):188-202.
Kim M, Carman CV, Yang W, Salas A, Springer TA. "The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2." The Journal of cell biology. 2004 167(6):1241-53.
2003 Sep 19
Kim M, Carman CV, Springer TA. "Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins." Science. 2003 Sep 19; 301(5640):1720-5.
2001 Oct 8
Christofi FL, Zhang H, Yu JG, Guzman J, Xue J, Kim M, Wang YZ, Cooke HJ. "Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system." The Journal of comparative neurology. 2001 Oct 8; 439(1):46-64.
2001 Oct
Kim M, Javed NH, Yu JG, Christofi F, Cooke HJ. "Mechanical stimulation activates Galphaq signaling pathways and 5-hydroxytryptamine release from human carcinoid BON cells." The Journal of clinical investigation. 2001 Oct; 108(7):1051-9.
Kim M, Cooke HJ, Javed NH, Carey HV, Christofi F, Raybould HE. "D-glucose releases 5-hydroxytryptamine from human BON cells as a model of enterochromaffin cells." Gastroenterology. 2001 121(6):1400-6.


CT Lefort and M. Kim. "Fluorescence resonance energy transfer in the studies of integrin activation.". Current Topics in Membrane. : Academic Press, 2011.
A. Schenkel and M. Kim. "Adhesion Molecules: Function and Inhibition.". Progress in Inflammation Research,. M.J. Parnham. Basel, Switzerland: Birkhauser Publishing, 2006.