Skip to main content
Explore URMC

Yi Zhang, Ph.D., M.S., M.B.A.


Showing all 31 journal articles & 0 books available

Journal Articles

Christodoulou C, Spencer JA, Yeh SA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Guo G, Seyedhassantehrani N, Esipova TV, Vinogradov SA, Rudzinskas S, Zhang Y, Perkins AS, Orkin SH, Calogero RA, Schroeder T, Lin CP, Camargo FD. "Live-animal imaging of native haematopoietic stem and progenitor cells." Nature.. 2020 Feb 5; Epub 2020 Feb 05.

Ayoub E, Wilson MP, McGrath KE, Li AJ, Frisch BJ, Palis J, Calvi LM, Zhang Y, Perkins AS. "EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription." Nature communications.. 2018 Oct 12; 9(1):4239. Epub 2018 Oct 12.

Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, Zhang Y, Perkins AS, Shannon K, Hemann MT, Puissant A, Stegmaier K. "The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia." Nature medicine.. 2017 Mar 0; 23(3):301-313. Epub 2017 Feb 13.

Wilson M, Tsakraklides V, Tran M, Xiao YY, Zhang Y, Perkins AS. "EVI1 Interferes with Myeloid Maturation via Transcriptional Repression of Cebpa, via Binding to Two Far Downstream Regulatory Elements." The Journal of biological chemistry.. 2016 Jun 24; 291(26):13591-607. Epub 2016 Apr 21.

Juneja SC, Vonica A, Zeiss C, Lezon-Geyda K, Yatsula B, Sell DR, Monnier VM, Lin S, Ardito T, Eyre D, Reynolds D, Yao Z, Awad HA, Yu H, Wilson M, Honnons S, Boyce BF, Xing L, Zhang Y, Perkins AS. "Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia." Bone.. 2014 Mar 0; 60:148-61. Epub 2013 Dec 04.

Glass C, Wilson M, Gonzalez R, Zhang Y, Perkins AS. "The role of EVI1 in myeloid malignancies." Blood cells, molecules & diseases.. 2014 53(1-2):67-76. Epub 2014 Feb 01.

Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG. "Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects." PloS one.. 2014 9(2):e89397. Epub 2014 Feb 27.

Zhang Y, Owens K, Hatem L, Glass CH, Karuppaiah K, Camargo F, Perkins AS. "Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia." Blood.. 2013 Oct 17; 122(16):2888-92. Epub 2013 Sep 10.

Arshad M, Ye Z, Gu X, Wong CK, Liu Y, Li D, Zhou L, Zhang Y, Bay WP, Yu VC, Li P. "RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1?)/c-Jun NH2-terminal kinase pathway." The Journal of biological chemistry.. 2013 Mar 22; 288(12):8726-36. Epub 2013 Feb 01.

Glass C, Wuertzer C, Cui X, Bi Y, Davuluri R, Xiao YY, Wilson M, Owens K, Zhang Y, Perkins A. "Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia." PloS one.. 2013 8(6):e67134. Epub 2013 Jun 27.

Zhang Y, Sicot G, Cui X, Vogel M, Wuertzer CA, Lezon-Geyda KA, Wheeler JC, Harki DA, Muzikar KA, Stolper DA, Dervan PB, Perkins AS. "Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide." Biochemistry.. 2011 Dec 6; 50(48):10431-41. Epub 2011 Nov 10.

Zhang Y, Stehling-Sun S, Lezon-Geyda K, Juneja SC, Coillard L, Chatterjee G, Wuertzer CA, Camargo F, Perkins AS. "PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function." Blood.. 2011 Oct 6; 118(14):3853-61. Epub 2011 Jun 10.

Cirone P, Lin S, Griesbach HL, Zhang Y, Slusarski DC, Crews CM. "A role for planar cell polarity signaling in angiogenesis." Angiogenesis.. 2008 11(4):347-60. Epub 2008 Sep 17.

Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM. "A chemical and genetic approach to the mode of action of fumagillin." Chemistry & biology.. 2006 Sep 0; 13(9):1001-9.

Yeh JR, Ju R, Brdlik CM, Zhang W, Zhang Y, Matyskiela ME, Shotwell JD, Crews CM. "Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest." Proceedings of the National Academy of Sciences of the United States of America.. 2006 Jul 5; 103(27):10379-10384. Epub 2006 Jun 21.

Cheung PY, Zhang Y, Long J, Lin S, Zhang M, Jiang Y, Wu Z. "p150(Glued), Dynein, and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs." The Journal of biological chemistry.. 2004 Oct 29; 279(44):45308-11. Epub 2004 Sep 16.

Rui HL, Fan E, Zhou HM, Xu Z, Zhang Y, Lin SC. "SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling." The Journal of biological chemistry.. 2002 Nov 8; 277(45):42981-6. Epub 2002 Sep 09.

Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC. "Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways." The Journal of biological chemistry.. 2002 May 17; 277(20):17706-12. Epub 2002 Mar 07.

Zhang Y, Qiu WJ, Liu DX, Neo SY, He X, Lin SC. "Differential molecular assemblies underlie the dual function of Axin in modulating the WNT and JNK pathways." The Journal of biological chemistry.. 2001 Aug 24; 276(34):32152-9. Epub 2001 Jun 14.

Fong CW, Zhang Y, Neo SY, Lin SC. "Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner." The Biochemical journal.. 2000 Dec 15; 352 Pt 3:747-53.

Zhang Y, Neo SY, Han J, Lin SC. "Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase." The Journal of biological chemistry.. 2000 Aug 11; 275(32):25008-14.

Neo SY, Zhang Y, Yaw LP, Li P, Lin SC. "Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate beta-catenin levels." Biochemical and biophysical research communications.. 2000 May 27; 272(1):144-50.

Zhang Y, Neo SY, Wang X, Han J, Lin SC. "Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling." The Journal of biological chemistry.. 1999 Dec 3; 274(49):35247-54.

Zhang Y, Neo SY, Han J, Yaw LP, Lin SC. "RGS16 attenuates galphaq-dependent p38 mitogen-activated protein kinase activation by platelet-activating factor." The Journal of biological chemistry.. 1999 Jan 29; 274(5):2851-7.

Zhang Y, Lin SC. "Molecular characterization of the cyclin-dependent kinase inhibitor p27 promoter." Biochimica et biophysica acta.. 1997 Sep 12; 1353(3):307-17.

Liu SY, Zhang WY, Li HY, Dai XJ, Zhang Y, Xu JC, Chen LL, Wang SQ, Qian CH. "[Studies on the isolation of endogenous sleep factors from Tupaia Belangeri Chinensis (TBC) after sleep deprivation]." Sheng li xue bao : [Acta physiologica Sinica].. 1994 Feb 0; 46(1):83-9.

Liu SY, Chen Ming, Zhang Yi, et al. "A study on circadian body termperature " clock" in young adult subjects." Acta psycholoica sinica. 1993; 25(3): 264-270.

Liu SY, Zhang WY, Zhang Y, Lin B, Ye YH, Yang L. "Somnogenic effects of isomeric oxidized glutathione (IGSSG) and oxidized glutathione (GSSG) isolated from roots of Panax ginseng (PG-R)." In: Du TC, Tam JP, Zhang YS, eds. Peptides - Biology and Chemistry. Leiden: ESCOM, 1993, pp. 101-2.

Liu S. Y, Zhang Y, Xu JC et al. "Pyrogenic effect and muramyl peptides,". In Du Y.C., Tam J.P. (eds) "Peptides - Biology and Chemistry", ESCOM, Leiden, 1993, pp. 81-82.

Xu JC, Chen LL, Liu SY, Zhang WY, Zhang Y, Dai XJ. "Synthesis of muramyl peptides,". In Du Y.C., Tam J.P. (eds) "Peptides - Biology and Chemistry", ESCOM, Leiden, 1993, pp. 153-157.

Liu SY, Zhang Y, Zhang WY, Dai XJ. "The pharmacological and toxocological studies of Sleep-Aid Tea (SAT)." Procedings of the 2nd Congress of the CSRS, 1996, 13-14. .