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Jennifer Jonason, Ph.D.

Contact Information

Phone Numbers

Office: (585) 276-5608

Fax: (585) 275-1121

Faculty Appointments

Biography

Research

The Jonason laboratory is interested in the signaling mechanisms that govern mesenchymal stem cell differentiation as well as maturation of committed chondrocytes and osteoblasts during skeletal development. Additionally, we have a strong interest in those mechanisms that function to maintain articular chondrocytes and the integrity of the articular cartilage matrix. We combine in vivo genetic mouse models with in vitro tissue culture and molecular biology techniques to better understand the role of specific signaling pathways and transcription factors in regulation of bone and joint development as well as in the onset and progression of osteoarthritis.

Credentials

Education

1999
BS | Otterbein College
Molecular Biology

2006
PhD | Yale University
Genetics

Post-doctoral Training & Residency

2007 - 2011
Post-doctoral Fellowship | Center for Musculoskeletal Research, University of Rochester | Mentor: Regis O'Keefe

Awards

2011
Young Investigator Travel Award
Sponsor: CMSR Annual Symposium
Location: University of Rochester

2008
Forum on Metabolic Bone Disease Travel Award
Location: Endocrine Fellows Foundation

2007 - 2010
National Research Service Award
Location: University of Rochester

1999
Outstanding Honor's Thesis
Location: Otterbein College

1999
Oustanding Senior Research Project
Location: Otterbein College

1998 - 1999
Mortar Board National College Senior Honor Society
Location: Otterbein College

1995 - 1999
Otterbein Scholar Award
Location: Otterbein College

1995 - 1999
Endowed Scholar Award
Location: Otterbein College

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Publications

Journal Articles

9/2019
Catheline SE, Hoak D, Chang M, Ketz JP, Hilton MJ, Zuscik MJ, Jonason JH. "Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2019 Sep 0; 34(9):1676-1689. Epub 2019 Jun 12.

4/12/2019
Feigenson M, Jonason JH, Shen J, Loiselle AE, Awad HA, O'Keefe RJ. "Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair." Annals of biomedical engineering.. 2019 Apr 12; Epub 2019 Apr 12.

5/2018
Yukata K, Xie C, Li TF, Brown ML, Kanchiku T, Zhang X, Awad HA, Schwarz EM, Beck CA, Jonason JH, O'Keefe RJ. "Teriparatide (human PTH) compensates for impaired fracture healing in COX-2 deficient mice." Bone.. 2018 May 0; 110:150-159. Epub 2018 Feb 03.

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