CONTACT INFORMATIONCREDENTIALSAWARDSPUBLICATIONSJennifer Jonason, Ph.D.Contact InformationPhone NumbersOffice: (585) 276-5608Fax: (585) 275-1121LocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 665Rochester, NY 14642BiographyResearchThe Jonason laboratory is interested in the signaling mechanisms that govern mesenchymal stem cell differentiation as well as maturation of committed chondrocytes and osteoblasts during skeletal development. Additionally, we have a strong interest in those mechanisms that function to maintain articular chondrocytes and the integrity of the articular cartilage matrix. We combine in vivo genetic mouse models with in vitro tissue culture and molecular biology techniques to better understand the role of specific signaling pathways and transcription factors in regulation of bone and joint development as well as in the onset and progression of osteoarthritis.CredentialsEducation1999BS | Otterbein CollegeMolecular Biology2006PhD | Yale UniversityGeneticsPost-doctoral Training & Residency2007 - 2011Post-doctoral Fellowship | Center for Musculoskeletal Research, University of Rochester | Mentor: Regis O'KeefeAwards2011Young Investigator Travel AwardSponsor: CMSR Annual SymposiumLocation: University of Rochester2008Forum on Metabolic Bone Disease Travel AwardLocation: Endocrine Fellows Foundation2007 - 2010National Research Service AwardLocation: University of Rochester1999Outstanding Honor's ThesisLocation: Otterbein College1999Outstanding Senior Research ProjectLocation: Otterbein College1998 - 1999Mortar Board National College Senior Honor SocietyLocation: Otterbein College1995 - 1999Otterbein Scholar AwardLocation: Otterbein College1995 - 1999Endowed Scholar AwardLocation: Otterbein CollegeVIEW ALL expand_morePublicationsJournal Articles11/17/2020Best KT, Nichols AEC, Knapp E, Hammert WC, Ketonis C, Jonason JH, Awad HA, Loiselle AE. "NF-?B activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival." Science signaling.. 2020 Nov 17; 13(658)Epub 2020 Nov 17. 9/2019Catheline SE, Hoak D, Chang M, Ketz JP, Hilton MJ, Zuscik MJ, Jonason JH. "Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2019 Sep; 34(9):1676-1689. Epub 2019 Jun 12. 4/12/2019Feigenson M, Jonason JH, Shen J, Loiselle AE, Awad HA, O'Keefe RJ. "Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair." Annals of biomedical engineering.. 2019 Apr 12; Epub 2019 Apr 12. VIEW ALL PUBLICATIONS