Lei Xu, Ph.D.

Lei Xu, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 633
Rochester, NY 14642

Fax: (585) 273-1450
Office: (585) 273-1302
Administrative: (585) 273-1440
Lab: (585) 276-4365

Journal Articles

Showing all 12 journal articles available.

2012 Apr
Yang L, Xu L. "GPR56 in cancer progression: current status and future perspective." Future oncology. 2012 Apr; 8(4):431-40.
Liquan Yang; Guangchun Chen; Sonali Mohanty; Glynis Scott; Febeha Fazal; Arshad Rahman; Shahinoor Begum; Richard O. Hynes; Lei Xu. "GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression." Cancer Research. 2011; 71: 5558-68.
Lei Xu; Shahinoor Begum; Marc Barry; Denise Crowley; Liquan Yang; Roderick T. Bronson; Richard O. Hynes. "GPR56 Plays Varying Roles in Endogenous Cancer Progression". Clinical and Experimental Metastasis. 2010; 27: 241-9.
Guangchun Chen; Liquan Yang; Shahinoor Begum; Lei Xu. "GPR56 Is Essential for Testis Development and Male Fertility in Mice." Developmental Dynamics. 2010; 239: 3358-67.
2008 May
Xu L, Shen SS, Hoshida Y, Subramanian A, Ross K, Brunet JP, Wagner SN, Ramaswamy S, Mesirov JP, Hynes RO. "Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases." Molecular cancer research : MCR. 2008 May; 6(5):760-9.
Shihong Li; Zhaohui Jin; Samir Koirala; Lihong Bu; Lei Xu; Richard O. Hynes; Chrisopher A. Walsh; Gabriel Corfas; Xianhua Piao. "GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination". J. Neurosciences. 2008; 28: 5817-5826.
2007 Jan 15
Xu L, Hynes RO. "GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment." Cell cycle. 2007 Jan 15; 6(2):160-5. Epub 2007 Jan 28.
2006 Jun 13
Xu L, Begum S, Hearn JD, Hynes RO. "GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis." Proceedings of the National Academy of Sciences of the United States of America. 2006 Jun 13; 103(24):9023-8. Epub 2006 Jun 06.
2001 Nov
Xu L, Paulsen J, Yoo Y, Goodwin EB, Strome S. "Caenorhabditis elegans MES-3 is a target of GLD-1 and functions epigenetically in germline development." Genetics. 2001 Nov; 159(3):1007-17.
2001 Nov
Xu L, Strome S. "Depletion of a novel SET-domain protein enhances the sterility of mes-3 and mes-4 mutants of Caenorhabditis elegans." Genetics. 2001 Nov; 159(3):1019-29.
2001 Apr 24
Xu L, Fong Y, Strome S. "The Caenorhabditis elegans maternal-effect sterile proteins, MES-2, MES-3, and MES-6, are associated in a complex in embryos." Proceedings of the National Academy of Sciences of the United States of America. 2001 Apr 24; 98(9):5061-6.
1999 Jan
Williams C, Xu L, Blumenthal T. "SL1 trans splicing and 3'-end formation in a novel class of Caenorhabditis elegans operon." Molecular and cellular biology. 1999 Jan; 19(1):376-83.


Lei Xu. "GPR56 Interacts with Extracellular Matrix and Regulates Cancer Progression.". Adhesion-GPCRs. : Landes Biosciences, 2010.