Zhongren Zhou, B.Med., Ph.D.

Zhongren Zhou, B.Med., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY 14642

Office: (585) 276-4718
Fax: (585) 276-2832
Administrative: (585) 275-1959

Journal Articles

Showing all 52 journal articles available.

2016 Jul 29
Choy B, LaLonde A, Que J, Wu T, Zhou Z. "MCM4 and MCM7, Potential Novel Proliferation Markers, Significantly Correlated with Ki67, Bmi1, and Cyclin E Expression in Esophageal Adenocarcinoma, Squamous Cell Carcinoma, and Precancerous Lesions." Human pathology. 2016 Jul 29; Epub 2016 Jul 29.
2016
Ghatak S, Reveiller M, Toia L, Ivanov AI, Zhou Z, Redmond EM, Godfrey TE, Peters JH. "Low pH Cause Dilation of Intercellular Spaces in In Vitro Stratified Primary Esophageal Cells, Possibly by Modulating Wnt Signaling". J Gastrointest Surg. 2016; 20(3): 500-9.
2016
Rong Lu, Y Zhang, S Wu, Y Xia, Z Zhou, I Tako, H Dong, M Bissonnette, J Sun. "Salmonella protein AvrA activates the STAT3 signaling pathway in colon cancer." Neoplasia. 2016; 18(5): 308-16.
2015 Jul 9
Huber AR, Tan D, Sun J, Dean D, Wu T, Zhou Z. "High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7." BMC gastroenterology. 2015 Jul 9; 15:80. Epub 2015 Jul 09.
2015
Jiang M; Ku WY; Zhou Z; Dellon ES; Falk GW; Nakagawa H; Wang ML; Liu K; Wang J; Katzka DA; Peters JH; Lan X; Que J. "BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis". J. Clin. Inves. 2015; 125(4): 1557-1568. Link
2015
Huber AR; Tan D; Sun J; Dean D; Wu T; Zhou Z. "High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7." BMC Gastroenterology. 2015; 15: 80. Link
2015
Wu S; Zhang YG; Lu R; Xia Y; Zhou D; Petrof EO; Claud EC; Chen D; Chang EB; Carmeliet G; Sun J. "Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis." Gut. 2015; 64(7): 1082-1094. Link
2015
Chuang KH; Whitney-Miller CL; Chu CY; Zhou Z; Dokus MK; Schmit S; Barry CT. "MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs via targeting TET1 invasive human HCC tumors." Hepatology. 2015; 62(2): 466-480. Link
2015
Costaldi ME; Lall A; Burack R; Zhou ZD. "Using Flow Cytometry for the Diagnosis of Lung Neuroendocrine Carcinoma With Samples From Endobronchial Ultrasound Fine Needle Aspiration and Pleural Fluid." J. Interdiscipl. Histopathol. 2015; 3(1): 3-8. Link
2015
AK.Martin and Z Zhou. "Endoscopic ultrasound-guided FNA for the Diagnosis of Pancreatic Cysts by Combined Cytopathology and Cystic Content Analysis." World Journal of Gastroenterologic endoscopy. 2015; 7(15).
2015
Yong-guo Zhang, Shaoping Wu, Rong Lu, Zhongren Zhou, Jingsong Zhou, Geert Carmeliet, Elaine Petrof, Erika C. Claud, and Jun Sun. "Tight junction CLDN2 gene is a direct target of the vitamin D receptor." Scientific Report. 2015; 5. Link
2014 Aug
Zhou Z, Xia Y, Bandla S, Zakharov V, Wu S, Peters J, Godfrey TE, Sun J. "Vitamin D receptor is highly expressed in precancerous lesions and esophageal adenocarcinoma with significant sex difference." Human pathology. 2014 Aug; 45(8):1744-51. Epub 2014 May 15.
2014 Jul
Bandla S, Peters JH, Ruff D, Chen SM, Li CY, Song K, Thoms K, Litle VR, Watson T, Chapurin N, Lada M, Pennathur A, Luketich JD, Peterson D, Dulak A, Lin L, Bass A, Beer DG, Godfrey TE, Zhou Z. "Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells." Annals of surgery. 2014 Jul; 260(1):72-80.
2014 Apr 17
Zhou Z, Bandla S, Ye J, Xia Y, Que J, Luketich JD, Pennathur A, Peters JH, Tan D, Godfrey TE. "Cyclin E involved in early stage carcinogenesis of esophageal adenocarcinoma by SNP DNA microarray and immunohistochemical studies." BMC gastroenterology. 2014 Apr 17; 14:78. Epub 2014 Apr 17.
2014
Costaldi ME; Zhou Z. "Case report: different metastatic components from anaplastic thyroid carcinoma in mediastinal and neck lymph nodes simultaneously diagnosed by FNA." Diagnostic Cytopathology. 2014; 42(8): 694-699. Link
2014
Zhang Y; Ren H; Wang L; Ning Z; Zhuang Y; Gan J; Chen S; Zhou D; Zhu H; Tan D; Zhang H. "Clinical impact of tumor-infiltrating inflammatory cells in primary small cell esophageal carcinoma." Int. J. Mol. Sci. 2014; 15(6): 9718-9734. Link
2014
Bandla S; Peters JH; Ruff D; Chen SM; Li CY; Song K; Thoms K; Litle VR; Watson T; Chapurin N; Lada M; Pennathur A; Luketich JD; Peterson D; Dulak A; Lin L; Bass A; Beer DG; Godfrey TE; Zhou Z. "Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells." Ann. Surg. 2014; 260(1): 72-80. Link
2014
Zhou Z; Bandla S; Ye J; Xia Y; Que J; Luketich JD; Pennathur A; Peters JH; Tan D; Godfrey TE. "Cyclin E involved in early stage carcinogenesis of esophageal adenocarcinoma by SNP DNA microarray and immunohistochemical studies." BMC Gastroenterology. 2014; 14: 78. Link
2014
Lu R; Wu S; Zhang YG; Xia Y; Liu X; Zheng Y; Chen H; Schaefer KL; Zhou Z; Bissonnette M; Li L; Sun J. "Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway." Oncogenesis. 2014; 3: e105. Link
2014
Kim J; Fox C; Peng S; Pusung M; Pectasides E; Matthee E; Hong YS; Do IG; Jang J; Thorner AR; Van Hummelen P; Rustgi AK; Wong KK.; Zhou Z; Tang P; Kim KM; Lee J; Bass AJ. "Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma." J. Clin. Invest. 2014; 124(12): 5145-5158. Link
2014
Zhou Z; Xia Y; Bandla S; Zakharov V; Wu S; Peters J; Godfrey TE; Sun J. "Vitamin D receptor is highly expressed in precancerous lesions and esophageal adenocarcinoma with significant sex difference." Human Path. 2014; 45(8): 1744-1751. Link
2014
Kim J, Fox C, Peng S, Pusung M, Pectasides E, Matthee E, Hong YS, Do IG, Jang J, Thorner AR, Van Hummelen P, Rustgi AK, Wong KK, Zhou Z, Tang P, Kim KM, Lee J, Bass AJ. "Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma." The Journal of clinical investigation. 2014 124(12):5145-58. Epub 2014 Nov 17.
2013 May
Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, Stewart C, Bandla S, Imamura Y, Schumacher SE, Shefler E, McKenna A, Carter SL, Cibulskis K, Sivachenko A, Saksena G, Voet D, Ramos AH, Auclair D, Thompson K, Sougnez C, Onofrio RC, Guiducci C, Beroukhim R, Zhou Z, Lin L, Lin J, Reddy R, Chang A, Landrenau R, Pennathur A, Ogino S, Luketich JD, Golub TR, Gabriel SB, Lander ES, Beer DG, Godfrey TE, Getz G, Bass AJ. "Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity." Nature genetics. 2013 May; 45(5):478-86. Epub 2013 Mar 24.
2013
Woolf KM; Liang H; Sletten ZJ; Russell DK; Bonfiglio TA; Zhou Z. "False-negative rate of endoscopic ultrasound-guided fine-needle aspiration for pancreatic solid and cystic lesions with matched surgical resections as the gold standard: one institution's experience." Cancer Cytopathology. 2013; 121(8): 449-458. Link
2013
Fernando HR; Pollan LD; Zhou Z. "Floor of mouth mass." Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 2013; 116(3): 270-274. Link
2013
Li Z; Zou X; Xie L; Dong H; Chen Y; Liu Q; Wu X; Zhou D; Tan D; Zhang H. "Prognostic importance and therapeutic implications of PAK1, a drugable protein kinase, in gastroesophageal junction adenocarcinoma." PLoS ONE. 2013; 8(11): e80665. Link
2013
Dulak AM, Stojanov P, Peng S, Lawrence MS, et al. "Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity." Nature Genetics. 2013; 45(5): 478-486. Link
2012 Oct 18
Choy B, Bandla S, Xia Y, Tan D, Pennathur A, Luketich JD, Godfrey TE, Peters JH, Sun J, Zhou Z. "Clinicopathologic characteristics of high expression of Bmi-1 in esophageal adenocarcinoma and squamous cell carcinoma." BMC gastroenterology. 2012 Oct 18; 12:146. Epub 2012 Oct 18.
2012
Reveiller M; Ghatak S; Toia L; Kalatskaya I; Stein L; D'Souza M; Zhou Z; Bandla S; Gooding WE; Godfrey TE; Peters JH. "Bile exposure inhibits expression of squamous differentiation genes in human esophageal epithelial cells." Ann. Surg. 2012; 255(6): 1113-1120. Link
2012
Choy B; Bandla S; Xia Y; Tan D; Pennathur A; Luketich JD; Godfrey TE; Peters JH; Sun J; Zhou Z. "Clinicopathologic characteristics of high expression of Bmi-1 in esophageal adenocarcinoma and squamous cell carcinoma." BMC Gastroenterology. 2012; 12: 146. Link
2011 Aug
Feng W, Zhou Z, Peters JH, Khoury T, Zhai Q, Wei Q, Truong CD, Song SW, Tan D. "Expression of insulin-like growth factor II mRNA-binding protein 3 in human esophageal adenocarcinoma and its precursor lesions." Archives of pathology & laboratory medicine. 2011 Aug; 135(8):1024-31.
2011 Jul 1
Ismail A, Bandla S, Reveiller M, Toia L, Zhou Z, Gooding WE, Kalatskaya I, Stein L, D'Souza M, Litle VR, Peters JH, Pennathur A, Luketich JD, Godfrey TE. "Early G? cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma." Clinical cancer research : an official journal of the American Association for Cancer Research. 2011 Jul 1; 17(13):4513-22. Epub 2011 May 18.
2011 Jul
Hu Y, Bandla S, Godfrey TE, Tan D, Luketich JD, Pennathur A, Qiu X, Hicks DG, Peters JH, Zhou Z. "HER2 amplification, overexpression and score criteria in esophageal adenocarcinoma." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2011 Jul; 24(7):899-907. Epub 2011 Apr 01.
2011
Dhingra S; Feng W; Brown RE; Zhou Z; Khoury T; Zhang R; Tan D. "Clinicopathologic significance of putative stem cell markers, CD44 and nestin, in gastric adenocarcinoma." Int. J. Clin. Exp. Pathol. 2011; 4(8): 733-741. Link
2011
Ismail A; Bandla S; Reveiller M; Toia L; Zhou Z; Gooding WE; Kalatskaya I; Stein L; D'Souza M; Litle VR; Peters JH; Pennathur A; Luketich JD; Godfrey TE. "Early G(1) cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma." Clin. Cancer Res. 2011; 17(13): 4513-4522. Link
2011
Feng W; Zhou Z; Peters JH; Khoury T; Zhai Q; Wei Q; Truong CD; Song SW; Tan D. "Expression of insulin-like growth factor II mRNA-binding protein 3 in human esophageal adenocarcinoma and its precursor lesions." Arch. Path. Lab Med. 2011; 135(8): 1024-1031. Link
2011
Hu Y; Bandla S; Godfrey TE; Tan D; Luketich JD; Pennathur A; Qiu X; Hicks DG; Peters JH; Zhou Z. "HER2 amplification, overexpression and score criteria in esophageal adenocarcinoma." Modern Pathology. 2011; 24(7): 899-907. Link
2011
Liu X; Wu S; Xia Y; Li XE; Zhou ZD; Sun J. "Wingless homolog Wnt11 suppresses bacterial invasion and inflammation in intestinal epithelial cells." Am. J. Physiol. Gastrointest. Liver Physiol. 2011; 301(6): G992-G1003. Link
2010
Sepesi B; Watson TJ; Zhou D; Polomsky M; Litle VR; Jones CE; Raymond DP; Hu R; Qiu X; Peters JH. "Are endoscopic therapies appropriate for superficial submucosal esophageal adenocarcinoma? An analysis of esophagectomy specimens." J. Am. Coll. Surg. 2010; 210(4): 418-427.
2007
Bagdasaryan R; Zhou Z; Tierno B; Rosenman D; Xu D. "Neutrophil VCS parameters are superior indicators for acute infection." Laboratory Hematology. 2007; 13(1): 12-16.
2002
Zhou Z; Davar G; Strichartz G. "Endothelin-1 (ET-1) selectively enhances the activation gating of tetrodotoxin-resistant sodium currents in rat sensory neurons: a mechanism for algogenic actions of ET-1." J Neurosci. 2002; 22(15): 6325-6330.
2002
Strichartz GR, Zhou Z, Sinnott C, Khodorova A. "Therapeutic concentrations of local anaesthetics unveil the potential role of sodium channels in neuropathic pain." Novartis Foundation symposium. 2002 241:189-201; discussion 202-5, 226-32.
2000
Zhou Z; Poon CS. "Field potential analysis of synaptic transmission in spiking neurons in a sparse and irregular neuronal structure in vitro." J Neurosci Methods. 2000; 94(2): 193-203. Link
2000
Poon CS; Zhou Z; Champagnat J. "NMDA receptor activity in utero averts respiratory depression and anomalous long-term depression in newborn mice." J. Neurosci. 2000; 20(9): RC73. Link
1999
Zhi Y; Wu J; Zhou Z. "Distribution of the cell bodies and dendrites of motoneurons innervating the bulbocavernosus in male". Chinese J. Neuroanatomy. 1999; 15(4): 340-342.
1998
Zhi Y; Lu H; Zhou Z; Li S. "Distribution and quantitative study of dendrites and cell bodies of motoneurons innervating the external anal sphincter in rat." Chinese J. Anatomy. 1998; 21(1): 26-30.
1997
Zhou Z; Champagnat J; Poon CS. "Phasic and long-term depression in brainstem NTS neurons: differing roles of AMPA receptor desensitization." J. Neurosci. 1997; 17(14): 5349-5356. Link
1996
Poon CS; Zhou Z; Champagnat J. "Synaptic plasticity in the brainstem". J. Physiology--Paris. 1996; 90(5): 427-428.
1993
Zhou Z; He L; Zhou J. "[Expression of C-fos protein in CNS following electro-acupuncture of the "quanliao" and the electrostimulation of the rat tail.] [Article in Chinese.]". [Zhen Ci Yan Jiu] Acupuncture Res. 1993; 18(1): 14-20. Link
1993
Zhou Z; Zhou J. "Co-localization of Fos-like protein and NA in pons and medulla neurons following electric acupuncture of "Quan-liao" and electric stimulation of the rat tail." Chinese J. Histochem. Cytochem. 1993; 2(2): 114-118.
1993
Zhou JX; Zhou Z. "Co-localization of serotonin and Fos-like protein in the rat CNS after electroacupuncture and pain stimulation." Acta Academiae Medicinae Shanghai. 1993; 20(1): 66-69.
1989
Zhou Z; Li SF. "Distribution of the somatostatin-like peptide and the dendrites of the motor neurons innervating the external anal sphincter of the rat investigated by combined CB-HRP retrograde tracing and immunocytochemistry." J. North China Coal Medical College. 1989; 5(2): 39-41.

Books

2013
Zhou Z, and Hicks DG. "HER2 Amplification or Overexpression in Upper GI Tract and Breast Cancer with Clinical Diagnosis and Treatment". Oncogene and Cancer--From Bench to Clinic. Yahwardiah Siregar. : InTech, 2013.
2008
Strichartz, GR, Zhou Z, Sinnott C, and Khodorova A.. "Therapeutic Concentrations of Local Anaesthetics Unveil the Potential Role of Sodium Channels in Neuropathic Pain". Sodium Channels and Neuronal Hyperexcitability. : Novartis Foundation, 2008. 189-205