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Lan Wei-Lapierre, Ph.D.


Showing all 24 journal articles & 1 books available

Journal Articles

Wei-LaPierre, L*^; Tylock, KM; Dirksen, RT. "Regulation of mitochondrial flashes in skeletal and cardiac muscles by cyclophilin-D and mitochondrial substrates". Archives of biochemistry and biophysics. 2018; .

McBride, S*; Wei-LaPierre, L*; McMurray, F; MacFarlane, M; Qiu, X; Dirksen, RT; Harper, M-E. "Skeletal muscle mitoflashes, pH, and the role of uncoupling protein-3". Archives of biochemistry and biophysics. 2018; .

Liu W, Klose A, Forman S, Paris ND, Wei-LaPierre L, Cortés-Lopéz M, Tan A, Flaherty M, Miura P, Dirksen RT, Chakkalakal JV. "Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration." eLife.. 2017 Jun 6; 6Epub 2017 Jun 06.

Wang W, Gong G, Wang X, Wei-LaPierre L, Cheng H, Dirksen RT, Sheu SS. "Mitochondrial Flash: Integrative Reactive Oxygen Species and pH Signals in Cell and Organelle Biology." Antioxidants & redox signaling.. 2016 Sep 20; 25(9):534-49. Epub 2016 Jul 14.

Michelucci A, Paolini C, Canato M, Wei-Lapierre L, Pietrangelo L, De Marco A, Reggiani C, Dirksen RT, Protasi F. "Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death." Anesthesiology.. 2015 Sep 0; 123(3):603-17.

Liu W, Wei-LaPierre L, Klose A, Dirksen RT, Chakkalakal JV. "Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions." eLife.. 2015 Aug 27; 4Epub 2015 Aug 27.

Lamboley CR, Kake Guena SA, Touré F, Hébert C, Yaddaden L, Nadeau S, Bouchard P, Wei-LaPierre L, Lainé J, Rousseau EC, Frenette J, Protasi F, Dirksen RT, Pape PC. "New method for determining total calcium content in tissue applied to skeletal muscle with and without calsequestrin." The Journal of general physiology.. 2015 Feb 0; 145(2):127-53.

Paolini C, Quarta M, Wei-LaPierre L, Michelucci A, Nori A, Reggiani C, Dirksen RT, Protasi F. "Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice." Skeletal muscle. 2015 5:10. Epub 2015 Apr 18.

Goonasekera SA, Davis J, Kwong JQ, Accornero F, Wei-LaPierre L, Sargent MA, Dirksen RT, Molkentin JD. "Enhanced Ca²? influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy." Human molecular genetics.. 2014 Jul 15; 23(14):3706-15. Epub 2014 Feb 20.

Wei-Lapierre L, Gong G, Gerstner BJ, Ducreux S, Yule DI, Pouvreau S, Wang X, Sheu SS, Cheng H, Dirksen RT, Wang W. "Respective contribution of mitochondrial superoxide and pH to mitochondria-targeted circularly permuted yellow fluorescent protein (mt-cpYFP) flash activity." The Journal of biological chemistry.. 2013 Apr 12; 288(15):10567-77. Epub 2013 Mar 01.

Wei-Lapierre L, Carrell EM, Boncompagni S, Protasi F, Dirksen RT. "Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue." Nature communications.. 2013 4:2805.

Tang ZZ, Yarotskyy V, Wei L, Sobczak K, Nakamori M, Eichinger K, Moxley RT, Dirksen RT, Thornton CA. "Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel." Human molecular genetics.. 2012 Mar 15; 21(6):1312-24. Epub 2011 Dec 02.

Rossi AE, Boncompagni S, Wei L, Protasi F, Dirksen RT. "Differential impact of mitochondrial positioning on mitochondrial Ca(2+) uptake and Ca(2+) spark suppression in skeletal muscle." American journal of physiology. Cell physiology.. 2011 Nov 0; 301(5):C1128-39. Epub 2011 Aug 17.

Wei L, Salahura G, Boncompagni S, Kasischke KA, Protasi F, Sheu SS, Dirksen RT. "Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2011 Sep 0; 25(9):3068-78. Epub 2011 Jun 06.

Tae H, Wei L, Willemse H, Mirza S, Gallant EM, Board PG, Dirksen RT, Casarotto MG, Dulhunty A. "The elusive role of the SPRY2 domain in RyR1." Channels.. 2011 5(2):148-60. Epub 2011 Mar 01.

Beard NA, Wei L, Dulhunty AF. "Ca(2+) signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin." European biophysics journal : EBJ.. 2009 Dec 0; 39(1):27-36. Epub 2009 May 12.

Wei L, Gallant EM, Dulhunty AF, Beard NA. "Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin." The international journal of biochemistry & cell biology.. 2009 Nov 0; 41(11):2214-24. Epub 2009 May 04.

Wei L, Hanna AD, Beard NA, Dulhunty AF. "Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle." Cell calcium.. 2009 May 0; 45(5):474-84. Epub 2009 Apr 18.

Beard NA, Wei L, Dulhunty AF. "Control of muscle ryanodine receptor calcium release channels by proteins in the sarcoplasmic reticulum lumen." Clinical and experimental pharmacology & physiology.. 2009 Mar 0; 36(3):340-5.

Beard NA, Wei L, Cheung SN, Kimura T, Varsányi M, Dulhunty AF. "Phosphorylation of skeletal muscle calsequestrin enhances its Ca2+ binding capacity and promotes its association with junctin." Cell calcium.. 2008 Oct 0; 44(4):363-73.

Wei L, Abdellatif YA, Liu D, Kimura T, Coggan M, Gallant EM, Beard NA, Board PG, Dulhunty AF. "Muscle-specific GSTM2-2 on the luminal side of the sarcoplasmic reticulum modifies RyR ion channel activity." The international journal of biochemistry & cell biology.. 2008 40(8):1616-28. Epub 2008 Jan 20.

Kimura T, Pace SM, Wei L, Beard NA, Dirksen RT, Dulhunty AF. "A variably spliced region in the type 1 ryanodine receptor may participate in an inter-domain interaction." The Biochemical journal.. 2007 Jan 1; 401(1):317-24.

Wei L, Varsányi M, Dulhunty AF, Beard NA. "The conformation of calsequestrin determines its ability to regulate skeletal ryanodine receptors." Biophysical journal.. 2006 Aug 15; 91(4):1288-301. Epub 2006 May 12.

Beard NA, Casarotto MG, Wei L, Varsányi M, Laver DR, Dulhunty AF. "Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation." Biophysical journal.. 2005 May 0; 88(5):3444-54. Epub 2005 Feb 24.

Books & Chapters

Chapter Title: Ryanodinopathies: RyR-Linked Muscle Diseases
Book Title: Current Topics in Membranes: Structure and Function of Calcium Release Channels
Author List: Wei, L, Dirksen RT.
Edited By: Irina I. Serysheva
Published By: Academic Press2010