Photo not available

Viktor Yarotskyy, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, NY 14642

Office: (585) 276-3070
Fax: (585) 273-2652

Journal Articles

Showing all 23 journal articles available.

Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. "Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function." Skeletal muscle. 2015 5:4. Epub 2015 Jan 29.
2014 Nov 4
Yarotskyy V, Dirksen RT. "Monovalent cationic channel activity in the inner membrane of nuclei from skeletal muscle fibers." Biophysical journal. 2014 Nov 4; 107(9):2027-36.
Yarotskyy V, Dirksen RT. "RGK proteins: fashioning muscle with “Rad” new brakes." Channels. 2014 8(4):286-7.
Yarotskyy V, Dirksen RT. "RGK proteins: fashioning muscle with “Rad” new brakes." Channels. 2014 8(4):286-7.
Yarotskyy V, Protasi F, Dirksen RT. "Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death." PloS one. 2013 8(10):e77633. Epub 2013 Oct 15.
2012 Jul 18
Yarotskyy V, Dirksen RT. "Temperature and RyR1 regulate the activation rate of store-operated Ca²+ entry current in myotubes." Biophysical journal. 2012 Jul 18; 103(2):202-11. Epub 2012 Jul 17.
2012 Apr
Yarotskyy V, Gao G, Peterson BZ, Elmslie KS. "Domain III regulates N-type (CaV2.2) calcium channel closing kinetics." Journal of neurophysiology. 2012 Apr; 107(7):1942-51. Epub 2011 Dec 28.
2012 Mar 15
Tang ZZ, Yarotskyy V, Wei L, Sobczak K, Nakamori M, Eichinger K, Moxley RT, Dirksen RT, Thornton CA. "Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel." Human molecular genetics. 2012 Mar 15; 21(6):1312-24. Epub 2011 Dec 02.
2012 Feb
Yarotskyy V, Elmslie KS. "Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivation." The Journal of pharmacology and experimental therapeutics. 2012 Feb; 340(2):463-72. Epub 2011 Nov 16.
2012 Jan 8
Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. "AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation." Nature medicine. 2012 Jan 8; 18(2):244-51. Epub 2012 Jan 08.
2011 May
Fassl J, High KM, Stephenson ER, Yarotskyy V, Elmslie KS. "The intravenous anesthetic propofol inhibits human L-type calcium channels by enhancing voltage-dependent inactivation." Journal of clinical pharmacology. 2011 May; 51(5):719-30. Epub 2010 Jun 14.
2010 Nov
Fedorenko O, Yarotskyy V, Duzhyy D, Marchenko S. "The large-conductance ion channels in the nuclear envelope of central neurons." Pflügers Archiv : European journal of physiology. 2010 Nov; 460(6):1045-50. Epub 2010 Oct 01.
2010 Sep
Yarotskyy V, Elmslie KS. "Interference between two modulators of N-type (CaV2.2) calcium channel gating demonstrates that omega-conotoxin GVIA disrupts open state gating." Biochimica et biophysica acta. 2010 Sep; 1798(9):1821-8. Epub 2010 May 13.
2010 Apr 7
Wang X, Gao G, Guo K, Yarotskyy V, Huang C, Elmslie KS, Peterson BZ. "Phospholemman modulates the gating of cardiac L-type calcium channels." Biophysical journal. 2010 Apr 7; 98(7):1149-59.
2010 Mar 30
Gowd KH, Yarotskyy V, Elmslie KS, Skalicky JJ, Olivera BM, Bulaj G. "Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA." Biochemistry. 2010 Mar 30; 49(12):2741-52.
2010 Jan 1
Yarotskyy V, Gao G, Du L, Ganapathi SB, Peterson BZ, Elmslie KS. "Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation." The Journal of biological chemistry. 2010 Jan 1; 285(1):43-53. Epub 2009 Nov 02.
2009 Nov 4
Yarotskyy V, Elmslie KS. "Open-state occupancy prevents gating charge relaxation of N-type (CaV2.2) calcium channels." Biophysical journal. 2009 Nov 4; 97(9):2446-55.
2009 Feb 1
Yarotskyy V, Gao G, Peterson BZ, Elmslie KS. "The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation." The Journal of physiology. 2009 Feb 1; 587(3):551-65. Epub 2008 Dec 15.
2009 Jan
Yarotskyy V, Elmslie KS. "omega-conotoxin GVIA alters gating charge movement of N-type (CaV2.2) calcium channels." Journal of neurophysiology. 2009 Jan; 101(1):332-40. Epub 2008 Oct 29.
2007 Oct
Yarotskyy V, Elmslie KS. "Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels." British journal of pharmacology. 2007 Oct; 152(3):386-95. Epub 2007 Aug 13.
2006 Nov
Martynyuk AE, Seubert CN, Yarotskyy V, Glushakov AV, Gravenstein N, Sumners C, Dennis DM. "Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders." Recent patents on CNS drug discovery. 2006 Nov; 1(3):261-70.
2005 Jun 15
Marchenko SM, Yarotskyy VV, Kovalenko TN, Kostyuk PG, Thomas RC. "Spontaneously active and InsP3-activated ion channels in cell nuclei from rat cerebellar Purkinje and granule neurones." The Journal of physiology. 2005 Jun 15; 565(Pt 3):897-910. Epub 2005 Mar 17.
2005 May
Yarotskyy V, Glushakov AV, Sumners C, Gravenstein N, Dennis DM, Seubert CN, Martynyuk AE. "Differential modulation of glutamatergic transmission by 3,5-dibromo-L-phenylalanine." Molecular pharmacology. 2005 May; 67(5):1648-54. Epub 2005 Feb 01.