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Viktor Yarotskyy, Ph.D.


Showing all 24 journal articles & 0 books available

Journal Articles

Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY. "Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3." Proceedings of the National Academy of Sciences of the United States of America.. 2017 Jan 10; 114(2):E228-E236. Epub 2016 Dec 21.

Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. "Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function." Skeletal muscle. 2015 5:4. Epub 2015 Jan 29.

Yarotskyy V, Dirksen RT. "Monovalent cationic channel activity in the inner membrane of nuclei from skeletal muscle fibers." Biophysical journal.. 2014 Nov 4; 107(9):2027-36.

Yarotskyy V, Dirksen RT. "RGK proteins: fashioning muscle with “Rad” new brakes." Channels.. 2014 8(4):286-7.

Yarotskyy V, Dirksen RT. "RGK proteins: fashioning muscle with “Rad” new brakes." Channels.. 2014 8(4):286-7.

Yarotskyy V, Protasi F, Dirksen RT. "Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death." PloS one. 2013 8(10):e77633. Epub 2013 Oct 15.

Yarotskyy V, Dirksen RT. "Temperature and RyR1 regulate the activation rate of store-operated Ca²+ entry current in myotubes." Biophysical journal.. 2012 Jul 18; 103(2):202-11. Epub 2012 Jul 17.

Yarotskyy V, Gao G, Peterson BZ, Elmslie KS. "Domain III regulates N-type (CaV2.2) calcium channel closing kinetics." Journal of neurophysiology.. 2012 Apr 0; 107(7):1942-51. Epub 2011 Dec 28.

Tang ZZ, Yarotskyy V, Wei L, Sobczak K, Nakamori M, Eichinger K, Moxley RT, Dirksen RT, Thornton CA. "Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel." Human molecular genetics.. 2012 Mar 15; 21(6):1312-24. Epub 2011 Dec 02.

Yarotskyy V, Elmslie KS. "Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivation." The Journal of pharmacology and experimental therapeutics.. 2012 Feb 0; 340(2):463-72. Epub 2011 Nov 16.

Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. "AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation." Nature medicine.. 2012 Jan 8; 18(2):244-51. Epub 2012 Jan 08.

Fassl J, High KM, Stephenson ER, Yarotskyy V, Elmslie KS. "The intravenous anesthetic propofol inhibits human L-type calcium channels by enhancing voltage-dependent inactivation." Journal of clinical pharmacology.. 2011 May 0; 51(5):719-30. Epub 2010 Jun 14.

Fedorenko O, Yarotskyy V, Duzhyy D, Marchenko S. "The large-conductance ion channels in the nuclear envelope of central neurons." Pflügers Archiv : European journal of physiology.. 2010 Nov 0; 460(6):1045-50. Epub 2010 Oct 01.

Yarotskyy V, Elmslie KS. "Interference between two modulators of N-type (CaV2.2) calcium channel gating demonstrates that omega-conotoxin GVIA disrupts open state gating." Biochimica et biophysica acta.. 2010 Sep 0; 1798(9):1821-8. Epub 2010 May 13.

Wang X, Gao G, Guo K, Yarotskyy V, Huang C, Elmslie KS, Peterson BZ. "Phospholemman modulates the gating of cardiac L-type calcium channels." Biophysical journal.. 2010 Apr 7; 98(7):1149-59.

Gowd KH, Yarotskyy V, Elmslie KS, Skalicky JJ, Olivera BM, Bulaj G. "Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA." Biochemistry.. 2010 Mar 30; 49(12):2741-52.

Yarotskyy V, Gao G, Du L, Ganapathi SB, Peterson BZ, Elmslie KS. "Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation." The Journal of biological chemistry.. 2010 Jan 1; 285(1):43-53. Epub 2009 Nov 02.

Yarotskyy V, Elmslie KS. "Open-state occupancy prevents gating charge relaxation of N-type (CaV2.2) calcium channels." Biophysical journal.. 2009 Nov 4; 97(9):2446-55.

Yarotskyy V, Gao G, Peterson BZ, Elmslie KS. "The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation." The Journal of physiology.. 2009 Feb 1; 587(3):551-65. Epub 2008 Dec 15.

Yarotskyy V, Elmslie KS. "omega-conotoxin GVIA alters gating charge movement of N-type (CaV2.2) calcium channels." Journal of neurophysiology.. 2009 Jan 0; 101(1):332-40. Epub 2008 Oct 29.

Yarotskyy V, Elmslie KS. "Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels." British journal of pharmacology.. 2007 Oct 0; 152(3):386-95. Epub 2007 Aug 13.

Martynyuk AE, Seubert CN, Yarotskyy V, Glushakov AV, Gravenstein N, Sumners C, Dennis DM. "Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders." Recent patents on CNS drug discovery. 2006 Nov 0; 1(3):261-70.

Marchenko SM, Yarotskyy VV, Kovalenko TN, Kostyuk PG, Thomas RC. "Spontaneously active and InsP3-activated ion channels in cell nuclei from rat cerebellar Purkinje and granule neurones." The Journal of physiology.. 2005 Jun 15; 565(Pt 3):897-910. Epub 2005 Mar 17.

Yarotskyy V, Glushakov AV, Sumners C, Gravenstein N, Dennis DM, Seubert CN, Martynyuk AE. "Differential modulation of glutamatergic transmission by 3,5-dibromo-L-phenylalanine." Molecular pharmacology.. 2005 May 0; 67(5):1648-54. Epub 2005 Feb 01.