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Zhenzhi Tang, Ph.D.


Showing all 15 journal articles & 0 books available

Journal Articles

Tanner MK, Tang Z, Thornton CA. "Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy." Nucleic acids research.. 2021 Jan 27; Epub 2021 Jan 27.

Angelbello AJ, Benhamou RI, Rzuczek SG, Choudhary S, Tang Z, Chen JL, Roy M, Wang KW, Yildirim I, Jun AS, Thornton CA, Disney MD. "A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex." Cell chemical biology.. 2020 Nov 5; Epub 2020 Nov 05.

Ketley A, Wojciechowska M, Ghidelli-Disse S, Bamborough P, Ghosh TK, Morato ML, Sedehizadeh S, Malik NA, Tang Z, Powalowska P, Tanner M, Billeter-Clark R, Trueman RC, Geiszler PC, Agostini A, Othman O, Bösche M, Bantscheff M, Rüdiger M, Mossakowska DE, Drewry DH, Zuercher WJ, Thornton CA, Drewes G, Uings I, Hayes CJ, Brook JD. "CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model." Science translational medicine.. 2020 Apr 29; 12(541)

Tylock KM, Auerbach DS, Tang ZZ, Thornton CA, Dirksen RT. "Biophysical mechanisms for QRS- and QTc-interval prolongation in mice with cardiac expression of expanded CUG-repeat RNA." The Journal of general physiology.. 2020 Feb 3; 152(2)

Carrell ST, Tang Z, Mohr S, Lambowitz AM, Thornton CA. "Detection of expanded RNA repeats using thermostable group II intron reverse transcriptase." Nucleic acids research.. 2018 Jan 9; 46(1):e1.

Rzuczek SG, Gao Y, Tang ZZ, Thornton CA, Kodadek T, Disney MD. "Features of modularly assembled compounds that impart bioactivity against an RNA target." ACS chemical biology.. 2013 Oct 18; 8(10):2312-21. Epub 2013 Sep 13.

Tang ZZ, Yarotskyy V, Wei L, Sobczak K, Nakamori M, Eichinger K, Moxley RT, Dirksen RT, Thornton CA. "Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel." Human molecular genetics.. 2012 Mar 15; 21(6):1312-24. Epub 2011 Dec 02.

Groom L, Muldoon SM, Tang ZZ, Brandom BW, Bayarsaikhan M, Bina S, Lee HS, Qiu X, Sambuughin N, Dirksen RT. "Identical de novo mutation in the type 1 ryanodine receptor gene associated with fatal, stress-induced malignant hyperthermia in two unrelated families." Anesthesiology.. 2011 Nov; 115(5):938-45.

Tang ZZ, Sharma S, Zheng S, Chawla G, Nikolic J, Black DL. "Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein." The Journal of biological chemistry.. 2011 Mar 25; 286(12):10007-16. Epub 2011 Jan 31.

Lee JA, Tang ZZ, Black DL. "An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons." Genes & development.. 2009 Oct 1; 23(19):2284-93. Epub 2009 Sep 17.

Tang ZZ, Zheng S, Nikolic J, Black DL. "Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins." Molecular and cellular biology.. 2009 Sep; 29(17):4757-65. Epub 2009 Jun 29.

Tang ZZ, Liao P, Li G, Jiang FL, Yu D, Hong X, Yong TF, Tan G, Lu S, Wang J, Soong TW. "Differential splicing patterns of L-type calcium channel Cav1.2 subunit in hearts of Spontaneously Hypertensive Rats and Wistar Kyoto Rats." Biochimica et biophysica acta.. 2008 Jan; 1783(1):118-30. Epub 2007 Nov 19.

Tang ZZ, Hong X, Wang J, Soong TW. "Signature combinatorial splicing profiles of rat cardiac- and smooth-muscle Cav1.2 channels with distinct biophysical properties." Cell calcium.. 2007 May; 41(5):417-28. Epub 2006 Sep 18.

Liao P, Yu D, Lu S, Tang Z, Liang MC, Zeng S, Lin W, Soong TW. "Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1.2 calcium channels." The Journal of biological chemistry.. 2004 Nov 26; 279(48):50329-35. Epub 2004 Sep 20.

Tang ZZ, Liang MC, Lu S, Yu D, Yu CY, Yue DT, Soong TW. "Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit." The Journal of biological chemistry.. 2004 Oct 22; 279(43):44335-43. Epub 2004 Aug 06.