Alin Vonica, M.D., Ph.D.

Alin Vonica, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY 14642

Office: (585) 275-2936
Lab: (585) 273-3076

Research Bio

The salivary glands are important for their physiological role in digestion and oral health, and the site of pathological processes, from autoimmune diseases to cancer. I am using my experience in vertebrate embryology and signal transduction to understand the molecular processes underlying the development, maintenance, and regeneration of normal salivary glands, as well as their pathological alteration in oncogenesis.

Awards & Honors (National)

Ruth L Kirschstein National Research Service Award | NICHD training grant | Sloan-Kettering Institute, New York 2002 - 2005

Awards & Honors (Local)

Best Talk Prize | Northeast Society for Developmental Biology | Woods Hole 2006
Jack and Susan Rudin Scholar in the Biomedical Sciences | Sloan-Kettering Institute, New York 1997 - 2000

Recent Journal Articles

Showing the 5 most recent journal articles. 8 available »

2013 Oct
Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E. "Coco regulates dorsoventral specification of germ layers via inhibition of TGF? signalling." Development. 2013 Oct; 140(20):4177-81. Epub 2013 Sep 11.
2012 Aug 17
Gao H, Chakraborty G, Lee-Lim AP, Mo Q, Decker M, Vonica A, Shen R, Brogi E, Brivanlou AH, Giancotti FG. "The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites." Cell. 2012 Aug 17; 150(4):764-79.
2012 Jul 10
Warmflash A, Zhang Q, Sorre B, Vonica A, Siggia ED, Brivanlou AH. "Dynamics of TGF-? signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4." Proceedings of the National Academy of Sciences of the United States of America. 2012 Jul 10; 109(28):E1947-56. Epub 2012 Jun 11.
2011 Feb 1
Vonica A, Rosa A, Arduini BL, Brivanlou AH. "APOBEC2, a selective inhibitor of TGF? signaling, regulates left-right axis specification during early embryogenesis." Developmental biology. 2011 Feb 1; 350(1):13-23. Epub 2010 Sep 27.
2010 Apr 15
Shimomura Y, Agalliu D, Vonica A, Luria V, Wajid M, Baumer A, Belli S, Petukhova L, Schinzel A, Brivanlou AH, Barres BA, Christiano AM. "APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex." Nature. 2010 Apr 15; 464(7291):1043-7.

Current Appointments

Research Assistant Professor - Department of Pathology and Laboratory Medicine (SMD) - Primary


Ph.D. | Cellular Biology | Weill Cornell Graduate School of Medical Studies/Sloan-Kettering Institute2002
M.D. | Cluj-Napoca Medical School1986

Post-Doctoral Training & Residency

Columbia University Medical Center, New York. Angela M. Christiano, Ph.D. APCDD1 is a novel inhibitor of BMP signaling. 2012
The Rockefeller University, New York. Ali H. Brivanlou, Ph.D. Regulation of Wnt and TGF beta signaling in vertebrate development. 2010