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Matthew D. Rand, Ph.D.


Showing all 58 journal articles & 1 books available

Journal Articles

Krout IN, Scrimale T, Vorojekina D, Boyd ES, Rand MD. "Organomercurial lyase (MerB)-mediated demethylation decreases bacterial methylmercury resistance in the absence of mercuric reductase (MerA)." Applied and environmental microbiology.. 2022 Feb 9; :aem0001022. Epub 2022 Feb 09.

Beamish CR, Love TM, Rand MD. "Developmental Toxicology of Metal Mixtures in : Unique Properties of Potency and Interactions of Mercury Isoforms." International journal of molecular sciences.. 2021 Nov 9; 22(22)Epub 2021 Nov 09.

Peppriell AE, Gunderson JT, Krout IN, Vorojeikina D, Rand MD. "Latent effects of early-life methylmercury exposure on motor function in Drosophila." Neurotoxicology and teratology.. 2021 Oct 14; :107037. Epub 2021 Oct 14.

Zavez A, Thurston SW, Rand MD, Mruzek DW, Love T, Smith T, Shamlaye CF, van Wijngaarden E. "Delivery Mode and Child Development at 20 Months of Age and 7 Years of Age in the Republic of Seychelles." Maternal and child health journal.. 2021 Oct 5; Epub 2021 Oct 05.

Gunderson JT, Peppriell AE, Krout IN, Vorojeikina D, Rand MD. "Neuroligin-1 is a mediator of methylmercury neuromuscular toxicity." Toxicological sciences : an official journal of the Society of Toxicology.. 2021 Sep 21; Epub 2021 Sep 21.

Pope Q, Rand MD. "Variation in Methylmercury Metabolism and Elimination in Humans: Physiological Pharmacokinetic Modeling highlights the role of gut biotransformation, skeletal muscle and hair." Toxicological sciences : an official journal of the Society of Toxicology.. 2021 Jan 22; Epub 2021 Jan 22.

Strain JJ, Love TM, Yeates AJ, Weller D, Mulhern MS, McSorley EM, Thurston SW, Watson GE, Mruzek D, Broberg K, Rand MD, Henderson J, Shamlaye CF, Myers GJ, Davidson PW, van Wijngaarden E. "Associations of prenatal methylmercury exposure and maternal polyunsaturated fatty acid status with neurodevelopmental outcomes at 7 years of age: results from the Seychelles Child Development Study Nutrition Cohort 2." The American journal of clinical nutrition.. 2020 Dec 17; Epub 2020 Dec 17.

Gunderson JT, Peppriell AE, Vorojeikina D, Rand MD. "Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development." Archives of toxicology.. 2020 Aug 20; Epub 2020 Aug 20.

Peppriell AE, Gunderson JT, Vorojeikina D, Rand MD. "Methylmercury myotoxicity targets formation of the myotendinous junction." Toxicology.. 2020 Aug 12; :152561. Epub 2020 Aug 12.

Rand MD, Conrad K, Marvin E, Harvey K, Henderson D, Tawil R, Sobolewski M, Cory-Slechta DA. "Developmental exposure to methylmercury and resultant muscle mercury accumulation and adult motor deficits in mice." Neurotoxicology.. 2020 Jul 28; Epub 2020 Jul 28.

Haraguchi K, Sakamoto M, Matsuyama A, Yamamoto M, Hung DT, Nagasaka H, Uchida K, Ito Y, Kodamantani H, Horvat M, Chan HM, Rand M, Cirtiu CM, Kim BG, Nielsen F, Yamakawa A, Mashyanov N, Panichev N, Panova E, Watanabe T, Kaneko N, Yoshinaga J, Herwati RF, Suoth AE, Akagi H. "Development of Human Hair Reference Material Supporting the Biomonitoring of Methylmercury." Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.. 2020 Mar 6; Epub 2020 Mar 06.

Culbreth M, Rand MD. "Methylmercury modifies temporally expressed myogenic regulatory factors to inhibit myoblast differentiation." Toxicology in vitro : an international journal published in association with BIBRA.. 2019 Nov 6; :104717. Epub 2019 Nov 06.

Rand, MD; Vorojeikina, D; Peppriell, A; Gunderson, J; Prince, LM. "Drosophotoxicology: Elucidating Kinetic and Dynamic Pathways of Methylmercury Toxicity in a Drosophila Model" . Front. Genet. 2019; .

Rand MD, Caito SW. "Variation in the biological half-life of methylmercury in humans: Methods, measurements and meaning." Biochimica et biophysica acta. General subjects.. 2019 Feb 8; Epub 2019 Feb 08.

Xu Y, Wahlberg K, Love TM, Watson GE, Yeates AJ, Mulhern MS, McSorley EM, Strain JJ, Davidson PW, Shamlaye CF, Rand MD, Myers GJ, van Wijngaarden E, Broberg K. "Associations of blood mercury and fatty acid concentrations with blood mitochondrial DNA copy number in the Seychelles Child Development Nutrition Study." Environment international.. 2019 Jan 17; 124:278-283. Epub 2019 Jan 17.

Rand MD, Vorojeikina D, Peppriell A, Gunderson J, Prince LM. "Drosophotoxicology: Elucidating Kinetic and Dynamic Pathways of Methylmercury Toxicity in a Drosophila Model." Frontiers in genetics.. 2019 10:666. Epub 2019 Aug 09.

Wahlberg K, Love TM, Pineda D, Engström K, Watson GE, Thurston SW, Yeates AJ, Mulhern MS, McSorley EM, Strain JJ, Smith TH, Davidson PW, Shamlaye CF, Myers GJ, Rand MD, van Wijngaarden E, Broberg K. "Maternal polymorphisms in glutathione-related genes are associated with maternal mercury concentrations and early child neurodevelopment in a population with a fish-rich diet." Environment international.. 2018 Jun 0; 115:142-149. Epub 2018 Mar 21.

Caito SW, Jackson BP, Punshon T, Scrimale T, Grier A, Gill SR, Love TM, Watson GE, van Wijngaarden E, Rand MD. "Editor's Highlight: Variation in Methylmercury Metabolism and Elimination Status in Humans Following Fish Consumption." Toxicological sciences : an official journal of the Society of Toxicology.. 2018 Feb 1; 161(2):443-453.

Prince LM, Rand MD. "Methylmercury exposure causes a persistent inhibition of myogenin expression and C2C12 myoblast differentiation." Toxicology.. 2018 Jan 15; 393:113-122. Epub 2017 Nov 15.

Llop S, Tran V, Ballester F, Barbone F, Sofianou-Katsoulis A, Sunyer J, Engström K, Alhamdow A, Love TM, Watson GE, Bustamante M, Murcia M, Iñiguez C, Shamlaye CF, Rosolen V, Mariuz M, Horvat M, Tratnik JS, Mazej D, van Wijngaarden E, Davidson PW, Myers GJ, Rand MD, Broberg K. "CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment." Environment international.. 2017 Aug 0; 105:34-42. Epub 2017 May 10.

Vorojeikina D, Broberg K, Love TM, Davidson PW, van Wijngaarden E, Rand MD. "Editor's Highlight: Glutathione S-Transferase Activity Moderates Methylmercury Toxicity During Development in Drosophila." Toxicological sciences : an official journal of the Society of Toxicology.. 2017 May 1; 157(1):211-221.

Prince LM, Rand MD. "Notch Target Gene E(spl)m? Is a Mediator of Methylmercury-Induced Myotoxicity in ." Frontiers in genetics.. 2017 8:233. Epub 2018 Jan 15.

Engström K, Love TM, Watson GE, Zareba G, Yeates A, Wahlberg K, Alhamdow A, Thurston SW, Mulhern M, McSorley EM, Strain JJ, Davidson PW, Shamlaye CF, Myers GJ, Rand MD, van Wijngaarden E, Broberg K. "Polymorphisms in ATP-binding cassette transporters associated with maternal methylmercury disposition and infant neurodevelopment in mother-infant pairs in the Seychelles Child Development Study." Environment international.. 2016 Sep 0; 94:224-229. Epub 2016 Jun 02.

Rand MD, Vorojeikina D, van Wijngaarden E, Jackson BP, Scrimale T, Zareba G, Love TM, Myers GJ, Watson G. "Methods for Individualized Determination of Methylmercury Elimination Rate and De-Methylation Status in Humans Following Fish Consumption." Toxicological sciences : an official journal of the Society of Toxicology.. 2016 Feb 0; 149(2):385-95. Epub 2015 Nov 15.

Prince L, Korbas M, Davidson P, Broberg K, Rand MD. "Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury." Toxicological sciences : an official journal of the Society of Toxicology.. 2014 Aug 1; 140(2):425-35. Epub 2014 May 25.

Rand MD. "A method of permeabilization of Drosophila embryos for assays of small molecule activity." Journal of visualized experiments : JoVE.. 2014 Jul 13; (89)Epub 2014 Jul 13.

Rand MD, Montgomery SL, Prince L, Vorojeikina D. "Developmental toxicity assays using the Drosophila model." Current protocols in toxicology. 2014 Feb 19; 59:1.12.1-20. Epub 2014 Feb 19.

Engel GL, Rand MD. "The Notch target E(spl)m? is a muscle-specific gene involved in methylmercury toxicity in motor neuron development." Neurotoxicology and teratology.. 2014 43:11-8. Epub 2014 Mar 13.

Montgomery SL, Vorojeikina D, Huang W, Mackay TF, Anholt RR, Rand MD. "Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myogenic and neuromuscular developmental pathways." PloS one.. 2014 9(10):e110375. Epub 2014 Oct 31.

Jebbett NJ, Hamilton JW, Rand MD, Eckenstein F. "Low level methylmercury enhances CNTF-evoked STAT3 signaling and glial differentiation in cultured cortical progenitor cells." Neurotoxicology.. 2013 Sep 0; 38:91-100. Epub 2013 Jul 08.

Rand MD, Lowe JA, Mahapatra CT. "Drosophila CYP6g1 and its human homolog CYP3A4 confer tolerance to methylmercury during development." Toxicology.. 2012 Oct 9; 300(1-2):75-82. Epub 2012 Jun 12.

Mahapatra CT, Rand MD. "Methylmercury tolerance is associated with the humoral stress factor gene Turandot A." Neurotoxicology and teratology.. 2012 Jul 0; 34(4):387-94. Epub 2012 Apr 24.

Engel GL, Delwig A, Rand MD. "The effects of methylmercury on Notch signaling during embryonic neural development in Drosophila melanogaster." Toxicology in vitro : an international journal published in association with BIBRA.. 2012 Apr 0; 26(3):485-92. Epub 2011 Dec 30.

Rand MD, Kearney AL, Dao J, Clason T. "Permeabilization of Drosophila embryos for introduction of small molecules." Insect biochemistry and molecular biology.. 2010 Nov 0; 40(11):792-804. Epub 2010 Aug 19.

Mahapatra CT, Bond J, Rand DM, Rand MD. "Identification of methylmercury tolerance gene candidates in Drosophila." Toxicological sciences : an official journal of the Society of Toxicology.. 2010 Jul 0; 116(1):225-38. Epub 2010 Apr 07.

Rand MD. "Drosophotoxicology: the growing potential for Drosophila in neurotoxicology." Neurotoxicology and teratology.. 2010 32(1):74-83. Epub 2009 Jun 24.

Rand MD, Dao JC, Clason TA. "Methylmercury disruption of embryonic neural development in Drosophila." Neurotoxicology.. 2009 Sep 0; 30(5):794-802. Epub 2009 May 04.

Rand MD, Bland CE, Bond J. "Methylmercury activates enhancer-of-split and bearded complex genes independent of the notch receptor." Toxicological sciences : an official journal of the Society of Toxicology.. 2008 Jul 0; 104(1):163-76. Epub 2008 Mar 25.

Delwig A, Rand MD. "Kuz and TACE can activate Notch independent of ligand." Cellular and molecular life sciences : CMLS.. 2008 Jul 0; 65(14):2232-43.

Cornbrooks C, Bland C, Williams DW, Truman JW, Rand MD. "Delta expression in post-mitotic neurons identifies distinct subsets of adult-specific lineages in Drosophila." Developmental neurobiology.. 2007 Jan 0; 67(1):23-38.

Bland C, Rand MD. "Methylmercury induces activation of Notch signaling." Neurotoxicology.. 2006 Dec 0; 27(6):982-91. Epub 2006 Apr 28.

Delwig A, Bland C, Beem-Miller M, Kimberly P, Rand MD. "Endocytosis-independent mechanisms of Delta ligand proteolysis." Experimental cell research.. 2006 May 1; 312(8):1345-60. Epub 2006 Feb 17.

Bland CE, Kimberly P, Rand MD. "Notch-induced proteolysis and nuclear localization of the Delta ligand." The Journal of biological chemistry.. 2003 Apr 18; 278(16):13607-10. Epub 2003 Feb 18.

Mishra-Gorur K, Rand MD, Perez-Villamil B, Artavanis-Tsakonas S. "Down-regulation of Delta by proteolytic processing." The Journal of cell biology.. 2002 Oct 28; 159(2):313-24. Epub 2002 Oct 28.

Rand MD, Grimm LM, Artavanis-Tsakonas S, Patriub V, Blacklow SC, Sklar J, Aster JC. "Calcium depletion dissociates and activates heterodimeric notch receptors." Molecular and cellular biology.. 2000 Mar 0; 20(5):1825-35.

Artavanis-Tsakonas S, Rand MD, Lake RJ. "Notch signaling: cell fate control and signal integration in development." Science.. 1999 Apr 30; 284(5415):770-6.

Qi H, Rand MD, Wu X, Sestan N, Wang W, Rakic P, Xu T, Artavanis-Tsakonas S. "Processing of the notch ligand delta by the metalloprotease Kuzbanian." Science.. 1999 Jan 1; 283(5398):91-4.

Rand MD, Lindblom A, Carlson J, Villoutreix BO, Stenflo J. "Calcium binding to tandem repeats of EGF-like modules. Expression and characterization of the EGF-like modules of human Notch-1 implicated in receptor-ligand interactions." Protein science : a publication of the Protein Society.. 1997 Oct 0; 6(10):2059-71.

Rand MD, Lock JB, van't Veer C, Gaffney DP, Mann KG. "Blood clotting in minimally altered whole blood." Blood.. 1996 Nov 1; 88(9):3432-45.

Rand MD, Hanson SR, Mann KG. "Factor V turnover in a primate model." Blood.. 1995 Oct 1; 86(7):2616-23.

Murray JM, Rand MD, Egan JO, Murphy S, Kim HC, Mann KG. "Factor VNew Brunswick: Ala221-to-Val substitution results in reduced cofactor activity." Blood.. 1995 Sep 1; 86(5):1820-7.

Kalafatis M, Bertina RM, Rand MD, Mann KG. "Characterization of the molecular defect in factor VR506Q." The Journal of biological chemistry.. 1995 Feb 24; 270(8):4053-7.

Kalafatis M, Rand MD, Mann KG. "The mechanism of inactivation of human factor V and human factor Va by activated protein C." The Journal of biological chemistry.. 1994 Dec 16; 269(50):31869-80.

Kalafatis M, Swords NA, Rand MD, Mann KG. "Membrane-dependent reactions in blood coagulation: role of the vitamin K-dependent enzyme complexes." Biochimica et biophysica acta.. 1994 Nov 29; 1227(3):113-29.

Rand MD, Kalafatis M, Mann KG. "Platelet coagulation factor Va: the major secretory platelet phosphoprotein." Blood.. 1994 Apr 15; 83(8):2180-90.

Kalafatis M, Rand MD, Mann KG. "Factor Va-membrane interaction is mediated by two regions located on the light chain of the cofactor." Biochemistry.. 1994 Jan 18; 33(2):486-93.

Kalafatis M, Rand MD, Jenny RJ, Ehrlich YH, Mann KG. "Phosphorylation of factor Va and factor VIIIa by activated platelets." Blood.. 1993 Feb 1; 81(3):704-19.

Kalafatis M, Krishnaswamy S, Rand MD, Mann KG. "Factor V." Methods in enzymology.. 1993 222:224-36.

Books & Chapters

Chapter Title: Methylmercury Effects on Neural Developmental Signaling Pathways.
Book Title: Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategi
Author List: Wand, C, and Slikker, W. Eds.
Published By: John Wiley & Sons., 2011.2011