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Yan Michael Li, M.D., Ph.D.

Cancer, Neurosurgery

Clinical Interests

Acoustic Neuroma; Brain Tumors; Complex Reconstruction; Cranial Surgery; Glioblastoma, Metastatic, Clinical Trials; Meningioma, General; Minimally Invasive Spine Surgery; Neuro-Oncology, Brain & Spine Cancer; Neurosurgery - Brain; Peripheral Nerve Surgery; Spinal Surgery; Spinal Tumors; Spine Oncology; Ulnar Nerve, Trauma, Carpal Tunnel

Contact Information

Phone Numbers

Appointment: (585) 225-5767

Office: (585) 225-5767

Office: (585) 276-3050

Fax: (585) 276-2281

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Biography

Dr. Yan Michael Li is an Assistant Professor in the Department of Neurosurgery and Oncology and an award-winning fellowship-trained neurosurgeon who specializes in the treatment of brain tumors and complex spine diseases.

Dr. Li has authored more than 40 scholarly articles in peer-reviewed journals such as Cancer Cell, Nature Medicine, JAMA Oncology, Cancer Research, Neurosurgery, Journal of Neuro-Oncology, World Neurosurgery, and Toxin. He has received Bittner Award on Brain Tumor Research from American Association of Neurological Surgeons and awards from the Department of Defense Cancer Research Program, and his patent of nanoparticle gene therapy has been adopted in NCI Clinical Trial. He is currently performing research focused on maximal safe resection of brain and spine tumor, surgical outcome study for complex brain and spine surgery, Cancer specific brain and spine tumor targeted therapy and local delivery.

Dr. Li received his medical degree from Peking Union Medical College and his PhD from University of Texas MD Anderson Cancer Center. He then completed neurosurgical residency and enfolded complex spine fellowship at State University of New York, fellowships at Dana Farber Cancer Center Boston Children Hospital and Brigham and Women's Hospital Harvard Medical School, as well as a Neurosurgical Oncology fellowship at University of Texas MD Anderson Cancer Center focusing complex brain and spine tumor surgery.

Professional Background

Dr. Li treats patients with brain and spine tumor, including gliomas, meningioma, metastatic disease, skull base lesions. He employs advanced awake mapping, imaging techniques, intraoperative navigation and microsurgery to ensure maximal tumor removal and achieve the safest possible surgical outcomes. Dr. Li has advanced training in some of the most leading-edge technologies available, allowing him to provide the latest, most efficient options for each patient. These technologies include minimally invasive and endoscopic surgery for spine, brain and skull base tumors, advanced laser surgery for brain and metastatic spine tumor, primary spine tumor en bloc resection, stereotactic radiosurgery. Furthermore, Dr. Li works with a multi-disciplinary team to ensure that the best possible treatment strategies are offered to his patients and individualized treatments for brain and spine tumors based on personal genomic profiling.

Dr. Li also has strong clinical interest in simple and complex spine surgery, minimally invasive spinal surgery, and computer-assisted spinal navigation surgery. He treats patients with broad aspects of spine diseases, including herniated disk disease with nerve compression, degenerative spine stenosis, complex spine tumor, spine trauma and spine deformity diseases. Dr. Li provides the latest and most efficient options for each patient with back pain, including minimally invasive herniated disk surgery through less than one inch incision, minimally invasive lateral or posterior spinal fusion surgery, artificial disc implants that allow for more mobility, revision spine surgery with reconstruction and spine deformity surgery. In order to achieve the very best in patient outcomes, Dr. Li's practice emphasizes an interdisciplinary approach to disease processes and he works very closely with other specialists such as pain specialists, neurologists and physical therapists.

Research

Dr. Li is currently performing research focused on maximal safe resection of brain and spine tumor, surgical outcome study for minimal invasive and complex spine surgery, Cancer specific brain and spine tumor targeted therapy and local delivery. He authored more than 40 scholarly articles in peer-reviewed journals such as Cancer Cell, Nature Medicine, JAMA Oncology, Cancer Research, J of Neurosurgery spine, Neurosurgery, Journal of Neuro-Oncology, World Neurosurgery, and Toxin et al. He has received awards from the Department of Defense Cancer Research Program and his patent of nanoparticle gene therapy has been adopted in NCI Clinical Trial.

Dr. Li received his medical degree from Peking Union Medical College and his PhD from University of Texas MD Anderson Cancer Center. He then completed neurosurgical residency and enfolded Complex Spine fellowship at State University of New York, fellowships at Dana Farber Cancer Center Boston Children Hospital and Brigham and Women's Hospital Harvard Medical School, as well as a Neurosurgical Oncology fellowship at University of Texas MD Anderson Cancer Center focusing complex brain and spine tumor surgery.

Credentials

Specialties

  • Neurological Surgery

Education

1998
MD | Peking Union Medical College
Medicine

2004
PhD | University of Texas Health Science Center MD Anderson Cancer Center
Gene & Development, Gene Therapy & Cancer Biology

Post-doctoral Training & Residency

07/01/2007 - 06/30/2013
Residency in Neurological Surgery at SUNY Syracuse Office of Graduate Medical Education

07/01/2006 - 06/30/2007
Internship in Surgery at SUNY Syracuse Office of Graduate Medical Education

04/01/2005 - 07/31/2006
Research in Surgical Oncology at Dana-Farber Cancer Institute

7/1/2013 - 6/30/2014
Fellowship in at University of Texas M D Anderson Cancer Center

1/1/2011 - 4/30/2011
Residency in Neurological Surgery at Harvard University Health Services

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Publications

Journal Articles

5/2018
Cheng X, Zhang L, Zhang K, Zhang G, Hu Y, Sun X, Zhao C, Li H, Li YM, Zhao J. "Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein." Annals of the rheumatic diseases.. 2018 May 0; 77(5):770-779. Epub 2018 Jan 17.

2/2018
Piper K, DeAndrea-Lazarus I, Algattas H, Kimmell KT, Towner J, Li YM, Walter K, Vates GE. "Risk Factors Associated with Readmission and Reoperation in Patients Undergoing Spine Surgery." World neurosurgery.. 2018 Feb 0; 110:e627-e635. Epub 2017 Nov 21.

1/2018
Cheng X, Zhang G, Zhang L, Hu Y, Zhang K, Sun X, Zhao C, Li H, Li YM, Zhao J. "Mesenchymal stem cells deliver exogenous miR-21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration." Journal of cellular and molecular medicine.. 2018 Jan 0; 22(1):261-276. Epub 2017 Aug 14.

Books & Chapters

2013
Chapter Title: Evaluation and Decision Making For Metastatic Spine Tumor
Book Title: AO Spine Master Series: Metastatic Spinal Tumor (Volume 1).
Author List: Li YM, Dirks M, Rhines L.
Published By: Thieme2013 in New York

2013
Chapter Title: Ocular and Orbital Lesions
Book Title: Principles and Practice of Stereotactic Radiosurgery
Author List: Li YM, Šimonová G, Lis?ák R, Novotný J. Sinlga A, and Chin L
Published By: Springer2013 in New York

2012
Chapter Title: Bispecific Targeted Toxin DTATEGF Against Metastatic NSCLC Brain Tumor
Book Title: Tumor of Central Nervous System
Author List: Hall WA, Huang J, Li YM
Published By: Springer2012 in New York

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