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Ananta Paine, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-2891

Research Labs

Molecular Mechanisms of Inflammatory Bone Diseases

Visit Molecular Mechanisms of Inflammatory Bone Diseases Lab Website

Faculty Appointments


Professional Background

Dr. Ananta Paine is working as a Research Assistant Professor in the Division of Allergy, Immunology and Rheumatology. He has his B.Sc. in Microbiology, M.Sc. in Bioinformatics and PhD in Immunology. He has completed his postdoctoral trainings at Hannover Medical School, Germany and Karolinska Institute, Sweden working in the field of inflammation, immune signaling and system biology research. He also worked as a visiting researcher in Rockefeller University and joined the University of Rochester as a Research Assistant Professor in 2015.


Dr. Ananta Paine, with his unique academic background and research training and exposure to diverse research areas, employs integrative approaches to address challenging research questions related to autoimmune bone diseases. His current research focuses on understanding the involved mechanisms for rheumatoid arthritis and psoriatic arthritis to find ways to treat these diseases. His current research projects combines the in silico approaches (such as literature and data mining, integrated analysis of transcriptomic, epigenetic and proteomic data) with standard laboratory techniques and high throughput experimentations (such as microarray, RNAseq and proteomics).



BSc | India-Univ of Pune, Pune

MSc | India-Univ of Pune, Pune

PhD | Germany-Hannover Med Sch

Post-doctoral Training & Residency

2013 - 2014
Visiting Researcher Molecular Medicine The Rockefeller University New York, NY

2011 - 2014
Post Doctoral Fellow Molecular Medicine Karolinska Institute Sweden

2008 - 2011
Post Doctoral Fellow Molecular Medicine Hannover Medical School Germany

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Journal Articles

Paine A.; Dorresteijn M. J.; Zilian E.; Maaike G.E.; Blasczyk R; Wagener F; Pickkers P.; Immenschuh S. "Lipopolysaccharide-Dependent Down-Regulation of Heme Oxygenase-1 via a Bach1-Regulated Pathway in Human Mononuclear". Free Radic Biol Med. 2014; S0891-5849(14): 1080-6.

Saragih, H; Zilian E; Jaimes Y'; Paine A; Figueiredo C; Eiz-Vesper B; Blasczyk R; Larmann J; Theilmeier G; Andrei-Selmer C; Becker J; Santoso S; Immenschuh S. "PECAM-1 Regulates Endothelial Heme Oxygenase-1 Expression via a Redox-dependent Nrf2-Mediated". Thrombosis and Haemostasis. 2014; 111(6).

Jagodic M; Stridh P; Gad AK; Paine A; Udekwu KI; Sjöholm LK; Svensson M; Pan-Hammarström Q;. "Nurture your scientific curiosity early in your research". Nat Genet. 2013; 45(2): 116-8.

Books & Chapters

Chapter Title: Breast Cancer MicroRNAs: Clinical Biomarkers for the Diagnosis and Treatment Strategies
Book Title: Omics Approaches in Breast Cancer: Towards Next-Generation Diagnosis, Prognosis, and Therapy
Author List: Shafi G, Tarique N Hasan, Syed N. A, Paine A, Tegner J, Munshi A.
Edited By: D. Barh
Published By: Springer India 2014

Chapter Title: Application of Bioinformatics in Drug designing in Antimalarial Drug Targets
Book Title: Current Trends in Pharmacology
Author List: Choudhary S, Paine A, Ghosh I,
Edited By: Ray, A and Gulati, K.
Published By: IK Publishing House 2007 in New Delhi