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Kyu Kwang Kim, Ph.D.

Publications

Showing all 36 journal articles & 1 books available

Journal Articles

2018
James NE, Cantillo E, Oliver MT, Rowswell-Turner RB, Ribeiro JR, Kim KK, Chichester CO 3rd, DiSilvestro PA, Moore RG, Singh RK, Yano N, Zhao TC. "HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells." Clin Exp Immunol. 2018; .

5/17/2016
Ribeiro JR, Schorl C, Yano N, Romano N, Kim KK, Singh RK, Moore RG. "HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells." Journal of ovarian research.. 2016 May 17; 9(1):28. Epub 2016 May 17.

11/16/2015
Kim KK, Han A, Yano N, Ribeiro JR, Lokich E, Singh RK, Moore RG. "Tetrathiomolybdate mediates cisplatin-induced p38 signaling and EGFR degradation and enhances response to cisplatin therapy in gynecologic cancers." Scientific reports.. 2015 Nov 16; 5:15911. Epub 2015 Nov 16.

10/15/2015
Kim KK, Abelman S, Yano N, Ribeiro JR, Singh RK, Tipping M, Moore RG. "Tetrathiomolybdate inhibits mitochondrial complex IV and mediates degradation of hypoxia-inducible factor-1? in cancer cells." Scientific reports.. 2015 Oct 15; 5:14296. Epub 2015 Oct 15.

6/30/2014
Lokich E, Singh RK, Han A, Romano N, Yano N, Kim K, Moore RG. "HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation." Scientific reports.. 2014 Jun 30; 4:5500. Epub 2014 Jun 30.

1/6/2014
Moore RG, Hill EK, Horan T, Yano N, Kim K, MacLaughlan S, Lambert-Messerlian G, Tseng YD, Padbury JF, Miller MC, Lange TS, Singh RK. "HE4 (WFDC2) gene overexpression promotes ovarian tumor growth." Scientific reports.. 2014 Jan 6; 4:3574. Epub 2014 Jan 06.

11/2013
Kawar N, Maclaughlan S, Horan TC, Uzun A, Lange TS, Kim KK, Hopson R, Singh AP, Sidhu PS, Glass KA, Shaw S, Padbury JF, Vorsa N, Arnold LA, Moore RG, Brard L, Singh RK. "PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models." Genes & cancer.. 2013 Nov 0; 4(11-12):524-34.

8/2012
Kristjansdottir K, Kim K, Choi JS, Horan TC, Brard L, Moore RG, Singh RK. "7 Methyl indole ethyl isothiocyanate causes ROS mediated apoptosis and cell cycle arrest in endometrial cancer cells." Gynecologic oncology.. 2012 Aug 0; 126(2):252-8. Epub 2012 May 02.

4/13/2012
Kim KK, Lange TS, Singh RK, Brard L, Moore RG. "Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C." BMC cancer.. 2012 Apr 13; 12:147. Epub 2012 Apr 13.

1/2012
Kim KK, Singh AP, Singh RK, Demartino A, Brard L, Vorsa N, Lange TS, Moore RG. "Anti-angiogenic activity of cranberry proanthocyanidins and cytotoxic properties in ovarian cancer cells." International journal of oncology.. 2012 Jan 0; 40(1):227-35. Epub 2011 Sep 12.

1/2012
Lange TS, Horan TC, Kim KK, Singh AP, Vorsa N, Brard L, Moore RG, Singh RK. "Cytotoxic properties of Adamantyl isothiocyanate and potential in vivo metabolite adamantyl-N-acetylcystein in gynecological cancer cells." Chemical biology & drug design.. 2012 Jan 0; 79(1):92-103. Epub 2011 Nov 04.

1/2012
Singh AP, Lange TS, Kim KK, Brard L, Horan T, Moore RG, Vorsa N, Singh RK. "Purified cranberry proanthocyanidines (PAC-1A) cause pro-apoptotic signaling, ROS generation, cyclophosphamide retention and cytotoxicity in high-risk neuroblastoma cells." International journal of oncology.. 2012 Jan 0; 40(1):99-108. Epub 2011 Oct 06.

2012
Moore RG, Lange TS, Robinson K, Kim KK, Uzun A, Horan TC, Kawar N, Yano N, Chu SR, Mao Q, Brard L, DePaepe ME, Padbury JF, Arnold LA, Brodsky A, Shen TL, Singh RK. "Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model." PloS one.. 2012 7(4):e34443. Epub 2012 Apr 03.

11/2011
Brard L, Lange TS, Robison K, Kim KK, Ara T, McCallum MM, Arnold LA, Moore RG, Singh RK. "Evaluation of the first Ergocalciferol-derived, non hypercalcemic anti-cancer agent MT19c in ovarian cancer SKOV-3 cell lines." Gynecologic oncology.. 2011 Nov 0; 123(2):370-8. Epub 2011 Jul 30.

7/22/2011
Stuckey A, Fischer A, Miller DH, Hillenmeyer S, Kim KK, Ritz A, Singh RK, Raphael BJ, Brard L, Brodsky AS. "Integrated genomics of ovarian xenograft tumor progression and chemotherapy response." BMC cancer.. 2011 Jul 22; 11:308. Epub 2011 Jul 22.

7/2011
Kim KK, Kawar NM, Singh RK, Lange TS, Brard L, Moore RG. "Tetrathiomolybdate induces doxorubicin sensitivity in resistant tumor cell lines." Gynecologic oncology.. 2011 Jul 0; 122(1):183-9. Epub 2011 May 06.

6/15/2011
Singh RK, Dorf L, DeMartino A, Illenye S, Koto K, Currier EA, Ashikaga T, Kim KK, Brard L, Sholler GL. "Oral RKS262 reduces tumor burden in a neuroblastoma xenograft animal model and mediates cytotoxicity through SAPK/JNK and ROS activation in vitro." Cancer biology & therapy.. 2011 Jun 15; 11(12):1036-45. Epub 2011 Jun 15.

5/2011
Koto KS, Lescault P, Brard L, Kim K, Singh RK, Bond J, Illenye S, Slavik MA, Ashikaga T, Saulnier Sholler GL. "Antitumor activity of nifurtimox is enhanced with tetrathiomolybdate in medulloblastoma." International journal of oncology.. 2011 May 0; 38(5):1329-41. Epub 2011 Mar 10.

4/29/2011
Kim KK, Singh RK, Strongin RM, Moore RG, Brard L, Lange TS. "Organometallic iron(III)-salophene exerts cytotoxic properties in neuroblastoma cells via MAPK activation and ROS generation." PloS one.. 2011 Apr 29; 6(4):e19049. Epub 2011 Apr 29.

2/2011
Singh RK, Lange TS, Kim KK, Brard L. "A coumarin derivative (RKS262) inhibits cell-cycle progression, causes pro-apoptotic signaling and cytotoxicity in ovarian cancer cells." Investigational new drugs.. 2011 Feb 0; 29(1):63-72. Epub 2009 Oct 29.

10/2010
Lange TS, Stuckey AR, Robison K, Kim KK, Singh RK, Raker CA, Brard L. "Effect of a vitamin D(3) derivative (B3CD) with postulated anti-cancer activity in an ovarian cancer animal model." Investigational new drugs.. 2010 Oct 0; 28(5):543-53. Epub 2009 Jul 07.

8/2010
Lange TS, Zou Y, Singh RK, Kim KK, Kristjansdottir K, Sholler GL, Brard L. "Chemotherapeutic effect of calcidiol derivative B3CD in a neuroblastoma xenograft model." Chemical biology & drug design.. 2010 Aug 0; 76(2):164-73. Epub 2010 May 11.

2/25/2010
Kim KK, Lange TS, Singh RK, Brard L. "Lipophilic aroylhydrazone chelator HNTMB and its multiple effects on ovarian cancer cells." BMC cancer.. 2010 Feb 25; 10:72. Epub 2010 Feb 25.

9/21/2009
Lange TS, McCourt C, Singh RK, Kim KK, Singh AP, Luisi BS, Alptürk O, Strongin RM, Brard L. "Apoptotic and chemotherapeutic properties of iron (III)-salophene in an ovarian cancer animal model." Drug design, development and therapy.. 2009 Sep 21; 3:17-26. Epub 2009 Sep 21.

8/2009
Singh AP, Singh RK, Kim KK, Satyan KS, Nussbaum R, Torres M, Brard L, Vorsa N. "Cranberry proanthocyanidins are cytotoxic to human cancer cells and sensitize platinum-resistant ovarian cancer cells to paraplatin." Phytotherapy research : PTR.. 2009 Aug 0; 23(8):1066-74.

2/6/2009
Brard L, Singh RK, Kim KK, Lange TS, Sholler GL. "Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells." Drug design, development and therapy.. 2009 Feb 6; 2:61-9. Epub 2009 Feb 06.

12/2/2008
Singh RK, Lange TS, Kim KK, Singh AP, Vorsa N, Brard L. "Isothiocyanate NB7M causes selective cytotoxicity, pro-apoptotic signalling and cell-cycle regression in ovarian cancer cells." British journal of cancer.. 2008 Dec 2; 99(11):1823-31. Epub 2008 Nov 11.

5/28/2008
Lange TS, Kim KK, Singh RK, Strongin RM, McCourt CK, Brard L. "Iron(III)-salophene: an organometallic compound with selective cytotoxic and anti-proliferative properties in platinum-resistant ovarian cancer cells." PloS one.. 2008 May 28; 3(5):e2303. Epub 2008 May 28.

5/2008
Singh RK, Lange TS, Kim KK, Shaw SK, Brard L. "A novel indole ethyl isothiocyanate (7Me-IEITC) with anti-proliferative and pro-apoptotic effects on platinum-resistant human ovarian cancer cells." Gynecologic oncology.. 2008 May 0; 109(2):240-9. Epub 2008 Mar 07.

2008
Brard L.; Singh R.K.; Lange T.S.; Kim K.; Singh A.P.; Hopson R.; Vorsa N. "Synthesis of Bicyclic Aryl Thiazolines with Selective Anti-Proliferative Effects on Human Cancer Cell Lines". Letters in organic chemistry. 2008; 5(2): 103-109.

11/1/2007
Singh RK, Lange TS, Kim K, Zou Y, Lieb C, Sholler GL, Brard L. "Effect of indole ethyl isothiocyanates on proliferation, apoptosis, and MAPK signaling in neuroblastoma cell lines." Bioorganic & medicinal chemistry letters.. 2007 Nov 1; 17(21):5846-52. Epub 2007 Aug 19.

10/2007
Lange TS, Singh RK, Kim KK, Zou Y, Kalkunte SS, Sholler GL, Swamy N, Brard L. "Anti-proliferative and pro-apoptotic properties of 3-bromoacetoxy calcidiol in high-risk neuroblastoma." Chemical biology & drug design.. 2007 Oct 0; 70(4):302-10.

9/20/2006
Jiang S, Escobedo JO, Kim KK, Alptürk O, Samoei GK, Fakayode SO, Warner IM, Rusin O, Strongin RM. "Stereochemical and regiochemical trends in the selective detection of saccharides." Journal of the American Chemical Society.. 2006 Sep 20; 128(37):12221-8.

11/16/2005
Wang W, Rusin O, Xu X, Kim KK, Escobedo JO, Fakayode SO, Fletcher KA, Lowry M, Schowalter CM, Lawrence CM, Fronczek FR, Warner IM, Strongin RM. "Detection of homocysteine and cysteine." Journal of the American Chemical Society.. 2005 Nov 16; 127(45):15949-58.

12/25/2003
Kim KK, Escobedo JO, St Luce NN, Rusin O, Wong D, Strongin RM. "Postcolumn HPLC detection of mono- and oligosaccharides with a chemosensor." Organic letters.. 2003 Dec 25; 5(26):5007-10.

5/8/2002
He M, Johnson RJ, Escobedo JO, Beck PA, Kim KK, St Luce NN, Davis CJ, Lewis PT, Fronczek FR, Melancon BJ, Mrse AA, Treleaven WD, Strongin RM. "Chromophore formation in resorcinarene solutions and the visual detection of mono- and oligosaccharides." Journal of the American Chemical Society.. 2002 May 8; 124(18):5000-9.

Books & Chapters

2006
Chapter Title: Detection of biological thiols
Book Title: Reviews in Fluorescence 2006
Author List: Escobedo JO, Rusin O, Wang W, Alptürk O, Kim KK, Xu X, Strongin RM
Published By: Springer US2006