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Patrick Brophy, M.D.

Publications

Showing all 107 journal articles & 22 books available

Journal Articles

11/18/2019
Starr MC, Boohaker L, Eldredge LC, Menon S, Griffin R, Mayock D, Askenazi D, Hingorani S, . "Acute Kidney Injury is Associated with Poor Lung Outcomes in Infants Born ?32 Weeks of Gestational Age." American journal of perinatology.. 2019 Nov 18; Epub 2019 Nov 18.

9/19/2019
Selewski DT, Gist KM, Nathan AT, Goldstein SL, Boohaker LJ, Akcan-Arikan A, Bonachea EM, Hanna M, Joseph C, Mahan JD, Mammen C, Nada A, Reidy K, Staples A, Wintermark P, Griffin R, Askenazi DJ, Guillet R, . "The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group." Pediatric research.. 2019 Sep 19; Epub 2019 Sep 19.

1/2019
Selewski DT, Akcan-Arikan A, Bonachea EM, Gist KM, Goldstein SL, Hanna M, Joseph C, Mahan JD, Nada A, Nathan AT, Reidy K, Staples A, Wintermark P, Boohaker LJ, Griffin R, Askenazi DJ, Guillet R, . "The impact of fluid balance on outcomes in critically ill near-term/term neonates: a report from the AWAKEN study group." Pediatric research.. 2019 Jan 0; 85(1):79-85. Epub 2018 Sep 20.

12/13/2018
Charlton JR, Boohaker L, Askenazi D, Brophy PD, Fuloria M, Gien J, Griffin R, Hingorani S, Ingraham S, Mian A, Ohls RK, Rastogi S, Rhee CJ, Revenis M, Sarkar S, Starr M, Kent AL, . "Late onset neonatal acute kidney injury: results from the AWAKEN Study." Pediatric research.. 2018 Dec 13; Epub 2018 Dec 13.

10/12/2018
Kirkley MJ, Boohaker L, Griffin R, Soranno DE, Gien J, Askenazi D, Gist KM, . "Correction to: Acute kidney injury in neonatal encephalopathy: an evaluation of the AWAKEN database." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2018 Oct 12; Epub 2018 Oct 12.

8/24/2018
Walker C, Echternacht H, Brophy PD. "Model for Medical Student Introductory Telemedicine Education." Telemedicine journal and e-health : the official journal of the American Telemedicine Association.. 2018 Aug 24; Epub 2018 Aug 24.

8/2018
Kraut EJ, Boohaker LJ, Askenazi DJ, Fletcher J, Kent AL, . "Incidence of neonatal hypertension from a large multicenter study [Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates-AWAKEN]." Pediatric research.. 2018 Aug 0; 84(2):279-289. Epub 2018 May 23.

1/2018
Starr MC, Askenazi DJ, Goldstein SL, MacDonald JW, Bammler TK, Afsharinejad Z, D Brophy P, Juul SE, Mayock DE, Hingorani SR. "Impact of processing methods on urinary biomarkers analysis in neonates." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2018 Jan 0; 33(1):181-186. Epub 2017 Aug 19.

1/2018
Mink R, Schwartz A, Carraccio C, High P, Dammann C, McGann KA, Kesselheim J, Herman B, . "Creating the Subspecialty Pediatrics Investigator Network." The Journal of pediatrics.. 2018 Jan 0; 192:3-4.e2.

12/2017
Huber JN, Hilkin BM, Hook JS, Brophy PD, Davenport TL, Davis JE, Colaizy TT, Moreland JG. "Neutrophil Phenotype Correlates With Postoperative Inflammatory Outcomes in Infants Undergoing Cardiopulmonary Bypass." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2017 Dec 0; 18(12):1145-1152.

11/7/2017
Rosner MH, Lew SQ, Conway P, Ehrlich J, Jarrin R, Patel UD, Rheuban K, Robey RB, Sikka N, Wallace E, Brophy P, Sloand J. "Perspectives from the Kidney Health Initiative on Advancing Technologies to Facilitate Remote Monitoring of Patient Self-Care in RRT." Clinical journal of the American Society of Nephrology : CJASN.. 2017 Nov 7; 12(11):1900-1909. Epub 2017 Jul 14.

11/2017
Jetton JG, Boohaker LJ, Sethi SK, Wazir S, Rohatgi S, Soranno DE, Chishti AS, Woroniecki R, Mammen C, Swanson JR, Sridhar S, Wong CS, Kupferman JC, Griffin RL, Askenazi DJ, . "Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study." The Lancet. Child & adolescent health.. 2017 Nov 0; 1(3):184-194.

10/2017
Zappitelli M, Ambalavanan N, Askenazi DJ, Moxey-Mims MM, Kimmel PL, Star RA, Abitbol CL, Brophy PD, Hidalgo G, Hanna M, Morgan CM, Raju TNK, Ray P, Reyes-Bou Z, Roushdi A, Goldstein SL. "Developing a neonatal acute kidney injury research definition: a report from the NIDDK neonatal AKI workshop." Pediatric research.. 2017 Oct 0; 82(4):569-573. Epub 2017 Jul 11.

9/2017
Brophy PD, Rasmussen M, Parida M, Bonde G, Darbro BW, Hong X, Clarke JC, Peterson KA, Denegre J, Schneider M, Sussman CR, Sunde L, Lildballe DL, Hertz JM, Cornell RA, Murray SA, Manak JR. "A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans." Genetics.. 2017 Sep 0; 207(1):215-228. Epub 2017 Jul 24.

4/2017
Tokhmafshan F, Brophy PD, Gbadegesin RA, Gupta IR. "Vesicoureteral reflux and the extracellular matrix connection." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2017 Apr 0; 32(4):565-576. Epub 2016 May 02.

4/2017
Brophy P. "The developing kidney: issues and opportunities." Seminars in fetal & neonatal medicine.. 2017 Apr 0; 22(2):57. Epub 2017 Feb 02.

4/2017
Brophy P. "Maternal determinants of renal mass and function in the fetus and neonate." Seminars in fetal & neonatal medicine.. 2017 Apr 0; 22(2):67-70.

3/20/2017
Kirresh T, Tuteja S, Russo D, Brophy PD, Murry DJ. "Development and validation of a liquid chromatography-mass spectrometric assay for simultaneous determination of tacrolimus and 13-O-desmethyl tacrolimus in rat kidney tissue." Journal of pharmaceutical and biomedical analysis.. 2017 Mar 20; 136:32-37. Epub 2016 Dec 29.

3/2017
Hanna MH, Dalla Gassa A, Mayer G, Zaza G, Brophy PD, Gesualdo L, Pesce F. "The nephrologist of tomorrow: towards a kidney-omic future." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2017 Mar 0; 32(3):393-404. Epub 2016 Mar 09.

1/5/2017
Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL, . "Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults." The New England journal of medicine.. 2017 Jan 5; 376(1):11-20. Epub 2016 Nov 18.

1/2017
Mercier K, McRitchie S, Pathmasiri W, Novokhatny A, Koralkar R, Askenazi D, Brophy PD, Sumner S. "Preterm neonatal urinary renal developmental and acute kidney injury metabolomic profiling: an exploratory study." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2017 Jan 0; 32(1):151-161. Epub 2016 Jul 19.

1/2017
Brophy PD. "Overview on the Challenges and Benefits of Using Telehealth Tools in a Pediatric Population." Advances in chronic kidney disease.. 2017 Jan 0; 24(1):17-21.

10/2016
Schwaderer AL, Wang H, Kim S, Kline JM, Liang D, Brophy PD, McHugh KM, Tseng GC, Saxena V, Barr-Beare E, Pierce KR, Shaikh N, Manak JR, Cohen DM, Becknell B, Spencer JD, Baker PB, Yu CY, Hains DS. "Polymorphisms in ?-Defensin-Encoding DEFA1A3 Associate with Urinary Tract Infection Risk in Children with Vesicoureteral Reflux." Journal of the American Society of Nephrology : JASN.. 2016 Oct 0; 27(10):3175-3186. Epub 2016 Mar 03.

8/2016
Hanna M, Brophy PD, Giannone PJ, Joshi MS, Bauer JA, RamachandraRao S. "Early urinary biomarkers of acute kidney injury in preterm infants." Pediatric research.. 2016 Aug 0; 80(2):218-23. Epub 2016 Apr 07.

8/2016
Harshman LA, Ng BG, Freeze HH, Trapane P, Dolezal A, Brophy PD, Brumbaugh JE. "Congenital nephrotic syndrome in an infant with ALG1-congenital disorder of glycosylation." Pediatrics international : official journal of the Japan Pediatric Society.. 2016 Aug 0; 58(8):785-8. Epub 2016 Jun 21.

4/2016
Dell KM, Matheson M, Hartung EA, Warady BA, Furth SL, . "Kidney Disease Progression in Autosomal Recessive Polycystic Kidney Disease." The Journal of pediatrics.. 2016 Apr 0; 171:196-201.e1. Epub 2016 Jan 28.

3/2016
Selewski DT, Chen A, Shatat IF, Pais P, Greenbaum LA, Geier P, Nelson RD, Kiessling SG, Brophy PD, Quiroga A, Seifert ME, Straatmann CE, Mahan JD, Ferris ME, Troost JP, Gipson DS. "Vitamin D in incident nephrotic syndrome: a Midwest Pediatric Nephrology Consortium study." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2016 Mar 0; 31(3):465-72. Epub 2015 Oct 23.

3/2016
Brophy PD. "Genetic Advances in Childhood Nephrological Disorders." Journal of pediatric genetics.. 2016 Mar 0; 5(1):1. Epub 2016 Jan 28.

2/2016
Elahi S, Homstad A, Vaidya H, Stout J, Hall G, Wu G, Conlon P, Routh JC, Wiener JS, Ross SS, Nagaraj S, Wigfall D, Foreman J, Adeyemo A, Gupta IR, Brophy PD, Rabinovich CE, Gbadegesin RA. "Rare variants in tenascin genes in a cohort of children with primary vesicoureteric reflux." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2016 Feb 0; 31(2):247-53. Epub 2015 Sep 25.

1/2016
Kogon AJ, Matheson MB, Flynn JT, Gerson AC, Warady BA, Furth SL, Hooper SR, , . "Depressive Symptoms in Children with Chronic Kidney Disease." The Journal of pediatrics.. 2016 Jan 0; 168:164-70.e1. Epub 2015 Oct 23.

2016
Jetton JG, Guillet R, Askenazi DJ, Dill L, Jacobs J, Kent AL, Selewski DT, Abitbol CL, Kaskel FJ, Mhanna MJ, Ambalavanan N, Charlton JR, . "Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates: Design of a Retrospective Cohort Study." Frontiers in pediatrics.. 2016 4:68. Epub 2016 Jul 19.

9/2015
Ha IS, Yap HK, Munarriz RL, Zambrano PH, Flynn JT, Bilge I, Szczepanska M, Lai WM, Antonio ZL, Gulati A, Hooman N, van Hoeck K, Higuita LM, Verrina E, Klaus G, Fischbach M, Riyami MA, Sahpazova E, Sander A, Warady BA, Schaefer F, . "Risk factors for loss of residual renal function in children treated with chronic peritoneal dialysis." Kidney international.. 2015 Sep 0; 88(3):605-13. Epub 2015 Apr 15.

7/2015
Gbadegesin RA, Adeyemo A, Webb NJ, Greenbaum LA, Abeyagunawardena A, Thalgahagoda S, Kale A, Gipson D, Srivastava T, Lin JJ, Chand D, Hunley TE, Brophy PD, Bagga A, Sinha A, Rheault MN, Ghali J, Nicholls K, Abraham E, Janjua HS, Omoloja A, Barletta GM, Cai Y, Milford DD, O'Brien C, Awan A, Belostotsky V, Smoyer WE, Homstad A, Hall G, Wu G, Nagaraj S, Wigfall D, Foreman J, Winn MP, . "HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome." Journal of the American Society of Nephrology : JASN.. 2015 Jul 0; 26(7):1701-10. Epub 2014 Oct 27.

6/2015
Hanna MH, Brophy PD. "Metabolomics in pediatric nephrology: emerging concepts." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2015 Jun 0; 30(6):881-7. Epub 2014 Jul 17.

2/26/2015
Basu RK, Kaddourah A, Terrell T, Mottes T, Arnold P, Jacobs J, Andringa J, Goldstein SL, . "Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in critically ill children (AWARE): study protocol for a prospective observational study." BMC nephrology.. 2015 Feb 26; 16:24. Epub 2015 Feb 26.

1/2015
Brophy PD, Shoham DA, , Charlton JR, Carmody J, Reidy KJ, Harshman L, Segar J, Askenazi D. "Early-life course socioeconomic factors and chronic kidney disease." Advances in chronic kidney disease.. 2015 Jan 0; 22(1):16-23.

12/2014
Harshman LA, Muff-Luett M, Neuberger ML, Dagle JM, Shilyansky J, Nester CM, Brophy PD, Jetton JG. "Peritoneal dialysis in an extremely low-birth-weight infant with acute kidney injury." Clinical kidney journal.. 2014 Dec 0; 7(6):582-5. Epub 2014 Sep 11.

10/2014
Khan I, Zimmerman B, Brophy P, Kamath S. "Masking of syndrome of inappropriate antidiuretic hormone secretion: the isonatremic syndrome." The Journal of pediatrics.. 2014 Oct 0; 165(4):722-6. Epub 2014 Jul 01.

2014
Picconi JL, Muff-Luett MA, Wu D, Bunchman E, Schaefer F, Brophy PD. "Kidney-specific expression of GFP by in-utero delivery of pseudotyped adeno-associated virus 9." Molecular therapy. Methods & clinical development.. 2014 1:14014. Epub 2014 May 07.

12/2013
Brophy PD, Alasti F, Darbro BW, Clarke J, Nishimura C, Cobb B, Smith RJ, Manak JR. "Genome-wide copy number variation analysis of a Branchio-oto-renal syndrome cohort identifies a recombination hotspot and implicates new candidate genes." Human genetics.. 2013 Dec 0; 132(12):1339-50. Epub 2013 Jul 13.

9/2013
Al-Uzri A, Matheson M, Gipson DS, Mendley SR, Hooper SR, Yadin O, Rozansky DJ, Moxey-Mims M, Furth SL, Warady BA, Gerson AC, . "The impact of short stature on health-related quality of life in children with chronic kidney disease." The Journal of pediatrics.. 2013 Sep 0; 163(3):736-41.e1. Epub 2013 Apr 26.

7/2013
Gbadegesin RA, Brophy PD, Adeyemo A, Hall G, Gupta IR, Hains D, Bartkowiak B, Rabinovich CE, Chandrasekharappa S, Homstad A, Westreich K, Wu G, Liu Y, Holanda D, Clarke J, Lavin P, Selim A, Miller S, Wiener JS, Ross SS, Foreman J, Rotimi C, Winn MP. "TNXB mutations can cause vesicoureteral reflux." Journal of the American Society of Nephrology : JASN.. 2013 Jul 0; 24(8):1313-22. Epub 2013 Apr 25.

6/2013
Brophy PD. "Changing the paradigm in pediatric acute kidney injury." The Journal of pediatrics.. 2013 Jun 0; 162(6):1094-6. Epub 2013 Feb 28.

5/2013
Hanna MH, Segar JL, Teesch LM, Kasper DC, Schaefer FS, Brophy PD. "Urinary metabolomic markers of aminoglycoside nephrotoxicity in newborn rats." Pediatric research.. 2013 May 0; 73(5):585-91. Epub 2013 Feb 14.

5/2013
Palevsky PM, Liu KD, Brophy PD, Chawla LS, Parikh CR, Thakar CV, Tolwani AJ, Waikar SS, Weisbord SD. "KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2013 May 0; 61(5):649-72. Epub 2013 Mar 15.

4/2013
Nester CM, Brophy PD. "Eculizumab in the treatment of atypical haemolytic uraemic syndrome and other complement-mediated renal diseases." Current opinion in pediatrics.. 2013 Apr 0; 25(2):225-31.

3/2013
Askenazi DJ, Goldstein SL, Koralkar R, Fortenberry J, Baum M, Hackbarth R, Blowey D, Bunchman TE, Brophy PD, Symons J, Chua A, Flores F, Somers MJ. "Continuous renal replacement therapy for children ?10 kg: a report from the prospective pediatric continuous renal replacement therapy registry." The Journal of pediatrics.. 2013 Mar 0; 162(3):587-592.e3. Epub 2012 Oct 24.

2/2013
Cooper CS, Birusingh KK, Austin JC, Knudson MJ, Brophy PD. "Distal ureteral diameter measurement objectively predicts vesicoureteral reflux outcome." Journal of pediatric urology.. 2013 Feb 0; 9(1):99-103. Epub 2012 Jan 09.

9/2012
Fleming GM, Walters S, Goldstein SL, Alexander SR, Baum MA, Blowey DL, Bunchman TE, Chua AN, Fletcher SA, Flores FX, Fortenberry JD, Hackbarth R, McBryde K, Somers MJ, Symons JM, Brophy PD, . "Nonrenal indications for continuous renal replacement therapy: A report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2012 Sep 0; 13(5):e299-304.

8/2012
Harshman LA, Brophy PD. "PAX2 in human kidney malformations and disease." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2012 Aug 0; 27(8):1265-75. Epub 2011 Dec 03.

4/2012
Harshman LA, Neuberger ML, Brophy PD. "Chronic hemodialysis in pediatric patients: technical and practical aspects of use." Minerva pediatrica.. 2012 Apr 0; 64(2):159-69.

2/9/2012
Nadim MK, Kellum JA, Davenport A, Wong F, Davis C, Pannu N, Tolwani A, Bellomo R, Genyk YS, . "Hepatorenal syndrome: the 8th International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group." Critical care : the official journal of the Critical Care Forum.. 2012 Feb 9; 16(1):R23. Epub 2012 Feb 09.

2/2012
Auron A, Brophy PD. "Hyperammonemia in review: pathophysiology, diagnosis, and treatment." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2012 Feb 0; 27(2):207-22. Epub 2011 Mar 23.

12/2011
Stewart ZA, Shetty R, Nair R, Reed AI, Brophy PD. "Case report: successful treatment of recurrent focal segmental glomerulosclerosis with a novel rituximab regimen." Transplantation proceedings.. 2011 Dec 0; 43(10):3994-6.

9/2011
Brophy PD. "Value of biomarkers to assess renal function following pediatric heart transplantation." Pediatric transplantation.. 2011 Sep 0; 15(6):543-5. Epub 2011 Jul 15.

7/2011
Dagle JM, Fisher TJ, Haynes SE, Berends SK, Brophy PD, Morriss FH, Murray JC. "Cytochrome P450 (CYP2D6) genotype is associated with elevated systolic blood pressure in preterm infants after discharge from the neonatal intensive care unit." The Journal of pediatrics.. 2011 Jul 0; 159(1):104-9. Epub 2011 Feb 24.

6/2011
Nester C, Stewart Z, Myers D, Jetton J, Nair R, Reed A, Thomas C, Smith R, Brophy P. "Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome." Clinical journal of the American Society of Nephrology : CJASN.. 2011 Jun 0; 6(6):1488-94. Epub 2011 May 26.

4/2010
Auron A, Brophy PD. "Pediatric renal supportive therapies: the changing face of pediatric renal replacement approaches." Current opinion in pediatrics.. 2010 Apr 0; 22(2):183-8.

2/2010
Sutherland SM, Zappitelli M, Alexander SR, Chua AN, Brophy PD, Bunchman TE, Hackbarth R, Somers MJ, Baum M, Symons JM, Flores FX, Benfield M, Askenazi D, Chand D, Fortenberry JD, Mahan JD, McBryde K, Blowey D, Goldstein SL. "Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2010 Feb 0; 55(2):316-25. Epub 2009 Dec 30.

3/2009
Gbadegesin R, Zhao S, Charpie J, Brophy PD, Smoyer WE, Lin JJ. "Significance of hemolysis on extracorporeal life support after cardiac surgery in children." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2009 Mar 0; 24(3):589-95. Epub 2008 Nov 12.

1/2009
Walters S, Porter C, Brophy PD. "Dialysis and pediatric acute kidney injury: choice of renal support modality." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2009 Jan 0; 24(1):37-48. Epub 2008 May 16.

12/2008
Zappitelli M, Goldstein SL, Symons JM, Somers MJ, Baum MA, Brophy PD, Blowey D, Fortenberry JD, Chua AN, Flores FX, Benfield MR, Alexander SR, Askenazi D, Hackbarth R, Bunchman TE, . "Protein and calorie prescription for children and young adults receiving continuous renal replacement therapy: a report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group." Critical care medicine.. 2008 Dec 0; 36(12):3239-45.

10/2008
Trachtman H, Hainer JW, Sugg J, Teng R, Sorof JM, Radcliffe J, . "Efficacy, safety, and pharmacokinetics of candesartan cilexetil in hypertensive children aged 6 to 17 years." The journal of clinical hypertension.. 2008 Oct 0; 10(10):743-50.

9/2008
Brophy PD. "Renal supportive therapy for pediatric acute kidney injury in the setting of multiorgan dysfunction syndrome/sepsis." Seminars in nephrology.. 2008 Sep 0; 28(5):457-69.

9/2008
Bunchman TE, Brophy PD, Goldstein SL. "Technical considerations for renal replacement therapy in children." Seminars in nephrology.. 2008 Sep 0; 28(5):488-92.

4/2008
Flores FX, Brophy PD, Symons JM, Fortenberry JD, Chua AN, Alexander SR, Mahan JD, Bunchman TE, Blowey D, Somers MJ, Baum M, Hackbarth R, Chand D, McBryde K, Benfield M, Goldstein SL. "Continuous renal replacement therapy (CRRT) after stem cell transplantation. A report from the prospective pediatric CRRT Registry Group." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2008 Apr 0; 23(4):625-30. Epub 2008 Jan 29.

2/2008
Pinsky MR, Brophy P, Padilla J, Paganini E, Pannu N. "Fluid and volume monitoring." The International journal of artificial organs.. 2008 Feb 0; 31(2):111-26.

2008
Gbadegesin R, Kudelka T, Gadegbeku CA, Brophy P, Smoyer WE, Lin JJ. "Arterial compliance in adolescents and young adults receiving chronic hemodialysis." Renal failure.. 2008 30(6):591-6.

2008
Bagshaw SM, Brophy PD, Cruz D, Ronco C. "Fluid balance as a biomarker: impact of fluid overload on outcome in critically ill patients with acute kidney injury." Critical care : the official journal of the Critical Care Forum.. 2008 12(4):169. Epub 2008 Jul 24.

12/2007
Cramer CH, Mills M, Valentini RP, Smoyer WE, Haftel H, Brophy PD. "Clinical presentation and outcome in a cohort of paediatric patients with membranous lupus nephritis." Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.. 2007 Dec 0; 22(12):3495-500. Epub 2007 Jul 29.

12/2007
Hackbarth R, Bunchman TE, Chua AN, Somers MJ, Baum M, Symons JM, Brophy PD, Blowey D, Fortenberry JD, Chand D, Flores FX, Alexander SR, Mahan JD, McBryde KD, Benfield MR, Goldstein SL. "The effect of vascular access location and size on circuit survival in pediatric continuous renal replacement therapy: a report from the PPCRRT registry." The International journal of artificial organs.. 2007 Dec 0; 30(12):1116-21.

12/2007
Betrus C, Remenapp R, Charpie J, Kudelka T, Brophy P, Smoyer WE, Lin JJ. "Enhanced hemolysis in pediatric patients requiring extracorporeal membrane oxygenation and continuous renal replacement therapy." Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia.. 2007 Dec 0; 13(6):378-83.

7/2007
Symons JM, Chua AN, Somers MJ, Baum MA, Bunchman TE, Benfield MR, Brophy PD, Blowey D, Fortenberry JD, Chand D, Flores FX, Hackbarth R, Alexander SR, Mahan J, McBryde KD, Goldstein SL. "Demographic characteristics of pediatric continuous renal replacement therapy: a report of the prospective pediatric continuous renal replacement therapy registry." Clinical journal of the American Society of Nephrology : CJASN.. 2007 Jul 0; 2(4):732-8. Epub 2007 May 18.

12/1/2006
Clarke JC, Patel SR, Raymond RM, Andrew S, Robinson BG, Dressler GR, Brophy PD. "Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage." Human molecular genetics.. 2006 Dec 1; 15(23):3420-8. Epub 2006 Oct 17.

12/2006
Stanley JC, Criado E, Upchurch GR, Brophy PD, Cho KJ, Rectenwald JE, , Kershaw DB, Williams DM, Berguer R, Henke PK, Wakefield TW. "Pediatric renovascular hypertension: 132 primary and 30 secondary operations in 97 children." Journal of vascular surgery.. 2006 Dec 0; 44(6):1219-28; discussion 1228-9. Epub 2006 Oct 20.

12/2006
Goldstein SL, Hackbarth R, Bunchman TE, Blowey D, Brophy PD, . "Evaluation of the PRISMA M10 circuit in critically ill infants with acute kidney injury: A report from the Prospective Pediatric CRRT Registry Group." The International journal of artificial organs.. 2006 Dec 0; 29(12):1105-8.

7/2006
Clarke JC, Honey EM, Bekker E, Snyman LC, Raymond RM, Lord C, Brophy PD. "A novel nonsense mutation in the EYA1 gene associated with branchio-oto-renal/branchiootic syndrome in an Afrikaner kindred." Clinical genetics.. 2006 Jul 0; 70(1):63-7.

6/2006
Barletta JF, Barletta GM, Brophy PD, Maxvold NJ, Hackbarth RM, Bunchman TE. "Medication errors and patient complications with continuous renal replacement therapy." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2006 Jun 0; 21(6):842-5. Epub 2006 Apr 19.

6/2006
McBryde KD, Kershaw DB, Bunchman TE, Maxvold NJ, Mottes TA, Kudelka TL, Brophy PD. "Renal replacement therapy in the treatment of confirmed or suspected inborn errors of metabolism." The Journal of pediatrics.. 2006 Jun 0; 148(6):770-8.

7/2005
Brophy PD, Somers MJ, Baum MA, Symons JM, McAfee N, Fortenberry JD, Rogers K, Barnett J, Blowey D, Baker C, Bunchman TE, Goldstein SL. "Multi-centre evaluation of anticoagulation in patients receiving continuous renal replacement therapy (CRRT)." Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.. 2005 Jul 0; 20(7):1416-21. Epub 2005 Apr 26.

3/2005
McBryde KD, Bunchman TE, Kudelka TL, Pasko DA, Brophy PD. "Hyperosmolar solutions in continuous renal replacement therapy for hyperosmolar acute renal failure: a preliminary report." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2005 Mar 0; 6(2):220-5.

2/2005
Goldstein SL, Somers MJ, Baum MA, Symons JM, Brophy PD, Blowey D, Bunchman TE, Baker C, Mottes T, McAfee N, Barnett J, Morrison G, Rogers K, Fortenberry JD. "Pediatric patients with multi-organ dysfunction syndrome receiving continuous renal replacement therapy." Kidney international.. 2005 Feb 0; 67(2):653-8.

2005
Mills M, White SC, Kershaw D, Flynn JT, Brophy PD, Thomas SE, Smoyer W. "Developing clinical protocols for nursing practice: improving nephrology care for children and their families." Nephrology nursing journal : journal of the American Nephrology Nurses' Association.. 2005 32(6):599-606; quiz 607.

5/25/2004
Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F. "SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes." Proceedings of the National Academy of Sciences of the United States of America.. 2004 May 25; 101(21):8090-5. Epub 2004 May 12.

4/2004
McBryde KD, Kudelka TL, Kershaw DB, Brophy PD, Gardner JJ, Smoyer WE. "Clearance of amino acids by hemodialysis in argininosuccinate synthetase deficiency." The Journal of pediatrics.. 2004 Apr 0; 144(4):536-40.

1/2004
Goldstein SL, Somers MJ, Brophy PD, Bunchman TE, Baum M, Blowey D, Mahan JD, Flores FX, Fortenberry JD, Chua A, Alexander SR, Hackbarth R, Symons JM. "The Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) Registry: design, development and data assessed." The International journal of artificial organs.. 2004 Jan 0; 27(1):9-14.

12/26/2003
Brophy PD, Lang KM, Dressler GR. "The secreted frizzled related protein 2 (SFRP2) gene is a target of the Pax2 transcription factor." The Journal of biological chemistry.. 2003 Dec 26; 278(52):52401-5. Epub 2003 Oct 15.

12/2003
Bunchman TE, Maxvold NJ, Brophy PD. "Pediatric convective hemofiltration: Normocarb replacement fluid and citrate anticoagulation." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2003 Dec 0; 42(6):1248-52.

10/15/2003
Cai Y, Brophy PD, Levitan I, Stifani S, Dressler GR. "Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation." The EMBO journal.. 2003 Oct 15; 22(20):5522-9.

5/2003
Symons JM, Brophy PD, Gregory MJ, McAfee N, Somers MJ, Bunchman TE, Goldstein SL. "Continuous renal replacement therapy in children up to 10 kg." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2003 May 0; 41(5):984-9.

12/2001
Brophy PD, Ostrom L, Lang KM, Dressler GR. "Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene." Development.. 2001 Dec 0; 128(23):4747-56.

12/2001
Bunchman TE, McBryde KD, Mottes TE, Gardner JJ, Maxvold NJ, Brophy PD. "Pediatric acute renal failure: outcome by modality and disease." Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2001 Dec 0; 16(12):1067-71.

12/2001
Li J, Li Y, Brophy PD, Kershawt DB. "Gene structure and alternative splicing of murine podocalyxin: a member of the CD34 sialomucin family." DNA sequence : the journal of DNA sequencing and mapping.. 2001 Dec 0; 12(5-6):407-12.

7/2001
Brophy PD, Mottes TA, Kudelka TL, McBryde KD, Gardner JJ, Maxvold NJ, Bunchman TE. "AN-69 membrane reactions are pH-dependent and preventable." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2001 Jul 0; 38(1):173-8.

7/2001
Flynn JT, Mottes TA, Brophy PD, Kershaw DB, Smoyer WE, Bunchman TE. "Intravenous nicardipine for treatment of severe hypertension in children." The Journal of pediatrics.. 2001 Jul 0; 139(1):38-43.

7/2001
Meyer RJ, Brophy PD, Bunchman TE, Annich GM, Maxvold NJ, Mottes TA, Custer JR. "Survival and renal function in pediatric patients following extracorporeal life support with hemofiltration." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2001 Jul 0; 2(3):238-242.

6/2001
Brophy PD, Thomas SE, McBryde KD, Bunchman TE. "Comparison of polyclonal induction agents in pediatric renal transplantation." Pediatric transplantation.. 2001 Jun 0; 5(3):174-8.

5/2001
Meyer RJ, Flynn JT, Brophy PD, Smoyer WE, Kershaw DB, Custer JR, Bunchman TE. "Hemodialysis followed by continuous hemofiltration for treatment of lithium intoxication in children." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2001 May 0; 37(5):1044-7.

2001
Flynn JT, Kershaw DB, Smoyer WE, Brophy PD, McBryde KD, Bunchman TE. "Peritoneal dialysis for management of pediatric acute renal failure." Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.. 2001 21(4):390-4.

5/2000
Brophy PD, Tenenbein M, Gardner J, Bunchman TE, Smoyer WE. "Childhood diethylene glycol poisoning treated with alcohol dehydrogenase inhibitor fomepizole and hemodialysis." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2000 May 0; 35(5):958-62.

4/2000
Bulloch B, Schubert CJ, Brophy PD, Johnson N, Reed MH, Shapiro RA. "Cause and clinical characteristics of rib fractures in infants." Pediatrics.. 2000 Apr 0; 105(4):E48.

2000
Schuerer DJ, Brophy PD, Maxvold NJ, Kudelka T, Bunchman TE. "High-efficiency dialysis for carbamazepine overdose." Journal of toxicology. Clinical toxicology.. 2000 38(3):321-3.

2/1993
Brophy PD, Borowski TB, Kokkinidis L. "Effects of scopolamine on the rewarding and seizure-inducing properties of amygdaloid stimulation." Pharmacology, biochemistry, and behavior.. 1993 Feb 0; 44(2):425-8.

Kompare M, Hanna M, Segar J and Brophy PD. "Carnitine excretion in ELBW and VLBW infants using a metabolomic approach.".

McConckey S, Pollard D, Brophy PD. "Healthcare Delivery in a developing nation: Lessons learned- Microsystems and reverse innovation". .

Kastl JT, Bunchman EC, Volk KA, Clarke JC, Brophy PD. "Paired-Box 2 Regulation of Disabled-2 Gene Expression.".

Muff-Luett M, Picconi JL, Wu D, Bunchman E, Chen YH, McCray P, Davidson BL, Brophy PD. "AAV9-Mediated Expression in Kidneys Following Systemic Delivery with a kidney specific promoter". .

Books & Chapters

2018
Book Title: Incidence of neonatal hypertension from a large multicenter study [Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates-AWAKEN]
Author List: Kraut EJ, Boohaker LJ, Askenazi DJ, Fletcher J, Kent AL; Neonatal Kidney Collaborative (NKC)
Published By: Pediatric Res.2018

2018
Book Title: Association Between Early Caffeine Citrate Administration and Risk of Acute Kidney Injury in Preterm Neonates: Results From the AWAKEN Study
Author List: Harer MW, Askenazi DJ, Boohaker LJ, Carmody JB, Griffin RL, Guillet R, Selewski DT, Swanson JR, Charlton JR; Neonatal Kidney Collaborative (NKC)
Published By: JAMA Pediatr2018

2012
Chapter Title: Creatinine Clearance in Pediatrics
Book Title: Encyclopedia of Intensive Care Medicine in Kellum
Author List: Nester C. and Brophy PD
Published By: Springer2012

2011
Book Title: Pediatric AKI- Up To Date
Author List: Jetton J and Brophy PD
Published By: none2011

2009
Chapter Title: Creatinine Clearance. Pediatric Nephrology
Book Title: A Handbook for Training Health Care Providers Publisher
Author List: Kastl JT and Brophy PD
Published By: World Scientific Publishing.2009

2008
Chapter Title: Technical aspects of pediatric renal replacement therapy
Book Title: In Intensive Care Medicine
Author List: Cramer C. Hackbarth R and Brophy PD
Edited By: Ronco C
Published By: none2008

2008
Chapter Title: treatment of Inborn Errors of Metabolism with CRRT
Book Title: Intensive Care Medicine
Author List: Walters S and Brophy PD
Edited By: Ronco C
Published By: none2008

2008
Chapter Title: Pediatric Acute Kidney Injury
Book Title: Clinician's Manual of Pediatric Nephrology Handbook
Author List: Lyon S, Brophy PD and Nester C
Published By: none2008

2008
Chapter Title: Creatinine Clearance
Book Title: Pediatric Nephrology: A Handbook for Training Health Care Providers
Author List: Kastl JT and Brophy PD
Published By: none2008

2008
Chapter Title: Fluid overload and nutrition in ECMO
Book Title: ECMO the red book
Author List: Fleming G and Brophy PD
Published By: none2008

2008
Book Title: Acute Kidney Injury: Prevention, causes and investigations
Author List: Brophy PD and Alexander S.
Edited By: Alexander S. and Schaefer F
Published By: Clinical Pediatric Nephrology2008

2008
Chapter Title: Neonatal Acute Kidney Injury
Book Title: Encyclopedia of Intensive Care Medicine in Kellum
Author List: Baack M. and Brophy PD
Published By: Springer2008

2008
Chapter Title: Acute renal failure: Prevention, causes and investigations
Book Title: Clinical Pediatric Nephrology
Author List: Phan, V, Brophy PD and Fleming G
Edited By: Geary D. and Schaefer F
Published By: Clinical Pediatric Nephrology2008

2008
Book Title: Multiple Organ System Extracorporeal Support in Critically Ill Children
Author List: Carcillo JA, Brophy P, Bunchman T, Butt W, Casey B, Dalton H, Dicarlo JV, Fleming G, Fortenberry J, Gaines B, Han YY, Kiss J, McMaster P, Mitzner S, Mok Q, Moritz M, Peters M, Wearden P.
Published By: Pediatric Clinics of North America2008

2006
Chapter Title: CVVH in Pediatric Patients
Book Title: Dialysis Therapy
Author List: Cramer C and Brophy PD
Edited By: Nissenson AR and Fine RN (
Published By: Hanley & Belfus, Inc2006

2006
Chapter Title: Acute Kidney Injury: Prevention, causes and investigations
Book Title: Clinical Pediatric Nephrology
Author List: Brophy PD and Alexander S.
Edited By: Alexander S. and Schaefer F.
Published By: Clinical Pediatric Nephrology2006

2005
Chapter Title: CVVH In Pediatric Patients
Book Title: Clinical Dialysis
Author List: Brophy PD and Bunchman TE
Edited By: Nissenson AR and Fine R
Published By: Edition McGraw-Hill Inc., Medical Publishing Division2005

2004
Chapter Title: Continuous Renal Replacement Therapies For Children With Acute Renal Failure and Metabolic Disorders
Book Title: Pediatric Dialysis
Author List: Gregory MJ, Bunchman TE and Brophy PD
Edited By: Warady BA, Fine RN, Alexander SR and Schaefer F
Published By: Kluwer Academic Publishers2004

2003
Book Title: Functional Development of The Kidney In Utero
Author List: Brophy PD and Robillard JE
Edited By: Polin R, Fox WW, Abman SH
Published By: Fetal and Neonatal Physiology2003

2002
Chapter Title: CAVH/CVVH In Pediatric Patients.
Book Title: Dialysis Therapy
Author List: Brophy PD, Maxvold NJ, Bunchman TE.
Edited By: Nissenson AR and Fine RN
Published By: Hanley & Belfus, Inc2002

2000
Chapter Title: Congenital Anomalies of the Kidney, Ureter, and Bladder
Book Title: In Kelley's Textbook of Internal Medicine
Author List: Brophy PD, Robillard JE.
Edited By: H. David Humes, MD. ED.
Published By: Lippincott, Williams & Wilkins Chapter2000

1998
Chapter Title: Cardiovascular/Renal, Electrolyte, and Respiratory/Allergy Chapters
Book Title: Pediatric Drug Dosage Handbook
Author List: Contributing Author
Edited By: Ellen Isaacs
Published By: Health Sciences Center, Winnipeg, Manitoba, Canada.1998