CONTACT INFORMATIONCREDENTIALSAWARDSPUBLICATIONSJing Wu, Ph.D.Contact InformationPhone NumbersOffice: (585) 275-5123Fax: (585) 276-1145LocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 675Rochester, NY 14642Faculty AppointmentsAssistant Professor - Department of Medicine , Nephrology (SMD) Assistant Professor - Department of Pharmacology and Physiology (SMD) - JointBiographyResearchI am interested in mechanisms regulating redox balance and inflammation in renal-cardiovascular health and disease. Specifically, research in my laboratory emphasizes adaptive immunity, vascular-immune interface, gene-environmental interactions, and hemodynamics in the pathogenesis of hypertension and chronic kidney disease. The long-term research objectives are to understand the nature of autoregulation in the kidney, the ability of the renal circulation to regulate electrolyte transport, and the vulnerability of these processes to genetic mutations, oxidative stress and inflammation in hypertension and chronic kidney diseases. Active projects include: 1. Novel Mechanisms Regulating Renal Perfusion and Kidney Redox Biology: Role in Salt Sensitive Hypertension (funded by a NIDDK K01, 2021-2025) 2. The Role of Cullin3 Ubiquitin Ligase in the Vascular-Immune Interface in Hypertension (funded by a University of Rochester Program for Advanced Immune Bioimaging Pilot Award) 3. Roles of Per- and Polyfluoroalkyl Substances (PFAS) in Hypertension and Chronic Kidney Disease (funded by a University of Rochester Environmental Health Science Center Pilot Award) My research is continuously supported by extramural funding from the NIH and American Heart Association. Our original research has been published on JCI, JCI Insight, Circulation Research, Cardiovascular Research, Hypertension, and Function including multiple first-author and/or corresponding-author publications. With a dedication to professional service, I am an Associate Editor at Frontiers in Physiology (Sections of Vascular Physiology and Renal and Epithelial Physiology), and I am a chair on the organization committee for the ASN Basic Research Forum for Emerging Kidney Scientists. I also serve on the AHA Fellowship/IPA Study Sections. I am committed to promoting innovative, collaborative, inclusive academic research and to mentoring young members of the research team. My ultimate career goal is to apply our findings to translational research that may lead to the development of novel therapies for cardiovascular, renal, and metabolic diseases. Email Address: Jing_Wu@URMC.Rochester.edu Twitter Handle: @JingWu_URMCCredentialsEducation2009BMed | Peking UniversityPreventive Medicine2014PhD | Vanderbilt University School of MedicinePharmacologyAwards2023 - 2023URMC Bioimaging Pilot Award: The Vascular-Immune Interface: Role of Cullin3 Ubiquitin LigaseSponsor: NIH/NIAID P01AI102851 (Fowell, Kim, MPI)Location: University of Rochester Program for Advanced Immune Bioimaging2022 - 2023EHSC Pilot Award: Role of PFAS in Hypertension and Chronic Kidney DiseaseSponsor: NIEHS P30ES001247 (PI: Paige Lawrence)Location: University of Rochester Environmental Health Science Center2021 - 2025K01 Research Scientist Development Award: Novel Mechanisms Regulating Renal Perfusion and Kidney Redox BiologySponsor: NIDDK K01 DK1267922021American Heart Association Council on Hypertension Stephanie Watts Career Development AwardSponsor: DataSci International: a radiotelemetry system ($50,000 value)2017 - 2019AHA AWRP Postdoctoral FellowshipSponsor: American Heart Association 17POST33660685 Total: $104,0602013 - 2014AHA Predoctoral FellowshipSponsor: AHA Greater Southeast Affiliate 13PRE14480008 Total: $50,360VIEW ALL expand_morePublicationsJournal Articles3/31/2022Fang S, Wu J, Reho JJ, Lu KT, Brozoski DT, Kumar G, Werthman AM, Silva SD, Muskus Veitia PC, Wackman KK, Mathison AJ, Teng BQ, Lin CW, Quelle FW, Sigmund CD. "RhoBTB1 reverses established arterial stiffness in angiotensin-II hypertension by promoting actin depolymerization." JCI insight.. 2022 Mar 31; Epub 2022 Mar 31. 1/2022Wu J, Sigmund CD. "Comorbidities Caused by a Corrupt Cullin 3: Lessons Learned From Bedside to Bench." Hypertension.. 2022 Jan; 79(1):76-78. Epub 2021 Dec 08. 2022Wu J, Fang S, Lu KT, Kumar G, Reho JJ, Brozoski DT, Otanwa AJ, Hu C, Nair AR, Wackman KK, Agbor LN, Grobe JL, Sigmund CD. "Endothelial Cullin3 Mutation Impairs Nitric Oxide-Mediated Vasodilation and Promotes Salt-Induced Hypertension." Function.. 2022 3(3):zqac017. Epub 2022 Apr 08. Books & Chapters2014 Chapter Title: Oxidative stress and hypertension Book Title: Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases Author List: Wu J, Harrison DG Published By: Springer-Verlag 2014 in LondonVIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Jing Wu, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Jing Wu, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.