URMC / Pharmacology & Physiology / Events Seminars & Events The weekly colloquium is generally held on Thursdays at 2:00 p.m. in K-207 Auditorium (2-6408). Unless otherwise noted, our departmental colloquia program is supported by the Alejandro Zaffaroni Endowment Fund and the John R. Murlin Fund. For outside guests, contact Dr. Houhui Xia. For graduate student colloquia, contact Dr. Cesare Orlandi. Upcoming20242023202220212020Research Seminar: Radiation Injury Links Mineral Homeostasis to Hematopoietic Stem Cell Niche ActivationCorey M. Hoffman - Graduate Student in the laboratory of Dr. Laura M. Calvi Dec 17, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)Guest Speaker: Genetic dissection of Activin and Inhibin Signaling in vivo: Some Surprises Along the WayDaniel J. Bernard, Ph.D. - Professor of Pharmacology and Therapeutics, McGill University, Montreal, Ontario, CA Dec 10, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)Host: Dr. Stephen R. Hammes Research Seminar: PI4P Hydrolysis is a Major Mechanism for GPCR-dependent DAG Generation and PKC/PKD ActivationRafael Gil de Rubio - Graduate Student in the laboratory of Dr. Alan V. Smrcka Dec 03, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)PhD Thesis Proposal: Isoform Specific PKC Regulation of the Cardiac Potassium Channel IKsChen Kaplan - Graduate Student in the laboratory of Dr. Coeli Lopes Dec 01, 2015 @ 2:00 p.m. Medical Center | 4-6912 (Anders Room)Faculty Candidate: Multi-faceted Roles of STIM-operated Ca2+ SignalingJonathan Soboloff, Ph.D. - Associate Professor, Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, PA Dec 01, 2015 @ 1:30 p.m. Medical Center | 1-9576 (Ryan Case Method Room)Research Seminar: Frizzled-2 Interacts with the Hippo Pathway to Impede Cardiomyocyte Dedifferentiation and ProliferationJoseph A. Bisson - Graduate Student in the laboratory of Dr. Ethan David Cohen Nov 12, 2015 @ 12:03 p.m. Medical Center | 4-6912 (Anders Room)Faculty Candidate: The Many Faces of RGS2 Protein RegulationBenita Sjogren, Ph.D. - Assistant Professor, Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI Nov 10, 2015 @ 3:00 p.m. Medical Center | 1-9576 (Ryan Case Method Room)PhD Thesis Proposal: The Development of Novel Acute Myocardial Infarction Therapeutics Using Metabolomics and High-Throughput ScreeningJimmy Zhang - Graduate Student in the laboratory of Dr. Paul S. Brookes Nov 09, 2015 @ 9:00 a.m. Medical Center | 4-6912 (Anders Room)Faculty Candidate: Beta-neurexin Proteins at the Synapse: Functional Link with the Endocannabinoid Signaling SystemGarret R. Anderson, Ph.D. - Postdoctoral Scholar, Department of Molecular and Cellular Physiology, Department of Psychiatry and Behavioral Science, Stanford University, Stanford, CA Nov 03, 2015 @ 10:00 a.m. Medical Center | 1-9576 (Ryan Case Method Room)Literature Reviews: Phosphodiesterase 9A Controls Nitric-oxide-independent cGMP and Hypertrophic Heart DiseaseSi (Vivian) Chen - Graduate Student in the laboratory of Dr. Chen Yan Oct 29, 2015 @ 1:00 p.m. Medical Center | 4-6912 (Anders Room)Literature Reviews: CCM1 Inhibits Sprouting Angiogenesis by Activating DELTA-NOTCH SignalingHarsha Swamy - Graduate Student in the laboratory of Dr. Angela J. Glading Oct 29, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)Faculty Candidate: Roles of Glial G Protein-coupled Receptors in Cellular and Cognitive FunctionsAnna G. Orr, Ph.D. - Staff Scientist, Gladstone Institute of Neurological Disease, The J. David Gladstone Institutes, San Francisco, CA Oct 20, 2015 @ 12:30 p.m. Medical Center | 2-6408 (K-207)Faculty Candidate: Where the Kidney Meets the Heart: Calcium Signaling, Cardiomyopathies and Polycystic Kidney DiseaseIvana Y. Kuo, Ph.D. - Postdoctoral Fellow, Department of Pharmacology, Yale University School of Medicine, New Haven, CT Oct 20, 2015 @ 10:00 a.m. Medical Center | 3-6408 (K-307)PhD Thesis Defense: mTOR-mediated Leiomyoma Growth in Uterine-specific Tsc2-null Mice is Exquisitely Dependent of Estradiol Signaling - Implications in the Treatment of Lymphangioleiomyomatosis (LAM)Hen Prizant - Graduate Student in the laboratory of Dr. Stephen R. Hammes Oct 15, 2015 @ 12:30 p.m. Medical Center | 1-9576 (Ryan Case Method Room)Literature Reviews: Loss of Tumor Suppressor REST in Uterine Fibroids (leiomyomas) Activates mTOR Pathway Through Increased GPCR 10 ExpressionManisha Taya - Graduate Student in the laboratory of Dr. Stephen R. Hammes Oct 08, 2015 @ 1:00 p.m. Medical Center | 4-6912 (Anders Room)Literature Reviews: A Novel Mechanism for the Up-regulation of EGF-receptor Levels in GlioblastomasXiaowen (Cindy) Wang - Graduate Student in the laboratory of Dr. Mark D. Noble Oct 08, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)Guest Speaker: Optogenetic Control of Mitochondrial Reactive Oxygen SpeciesAndrew J. Wojtovich, Ph.D. - Assistant Professor, Department of Anesthesiology, University of Rochester Oct 01, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)PhD Thesis Proposal - The Mechanism of Orai1-dependent Pathogenesis in Tubular Aggregate MyopathyLaura McMahon - Graduate Student in the laboratory of Dr. Robert T. Dirksen Sep 29, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)PhD Thesis Proposal - Mechanism of Action of Small Molecule Modulators of G beta-gamma SignalingIsaac J. Fisher - Graduate Student in the laboratory of Dr. Alan V. Smrcka Sep 24, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)PhD Thesis Proposal: Defining the Group IV Adhesion G Protein-coupled Receptor Mechanism of Activation and Therapeutic Potential for Melanoma TreatmentAlexander G. Hajduczok - Graduate Student in the laboratory of Dr. Gregory G. Tall Sep 23, 2015 @ 10:30 a.m. Medical Center | 4-6912 (Anders Room)PhD Thesis Proposal - Acoustic Modification of Collagen Structure and Bioactivity for the Treatment of Chronic and Hard to Heal WoundsEmma W. Grygotis - Graduate Student in the laboratory of Dr. Denise C. Hocking Sep 22, 2015 @ 10:00 a.m. Medical Center | 4-6912 (Anders Room)Literature Reviews: RIT1 Loss of Function Causes ROS-dependent Upregulation of c-JunNicholas Nobiletti - Graduate Student in the laboratory of Dr. Angela J. Glading Sep 17, 2015 @ 1:00 p.m. Medical Center | 4-6912 (Anders Room)Literature Reviews: Identification of a New Therapeutic Target in Relapsed Acute Lymphoblastic LeukemiaEdward Ayoub - Graduate Student in the laboratories of Dr. Archibald Perkins and Dr. Alan Smrcka Sep 17, 2015 @ 12:30 p.m. Medical Center | 4-6912 (Anders Room)Guest Speaker: Molecular Control of Synaptic Vesicle FusionJeremy S. Dittman, M.D., Ph.D. - Associate Professor of Biochemistry, Weill Cornell Medical College, New York, NY Sep 10, 2015 @ 12:20 p.m. Medical Center | 4-6912 (Anders Room)Host: Dr. Paul J. Kammermeier