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Primary Faculty

Jean Bidlack
Pharmacology of brain and lymphocytic opioid receptors
Joe Chakkalakal
Cellular and molecular mechanisms that regulate skeletal muscle growth, maintenance, and regeneration
Robert Dirksen
Molecular Mechanisms of Calcium Signaling in Striated Muscle
Robert Freeman
Molecular biology of programmed cell death
Angela Glading
Role of cell-cell contact in regulating cellular function in both the normal and disease state
Suzanne Haber
Basal ganglia and degenerative diseases
Denise Hocking
Regulation of cell behavior by the extracellular matrix
Paul Kammermeier
G protein coupled receptor signaling and modulation of ion channels in neurons
Whasil Lee
Mechanotransduction of musculoskeletal cells and associated human disease; Physiology and pathophysiology of mechanosensitive ion channels
John Lueck
Use of engineered tRNAs for suppression of nonsense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) transcripts as therapeutic intervention for cystic fibrosis
David MacLean
Mechanisms of neurotransmitter receptor function
Trevor Shuttleworth
The nature of the conductances responsible for agonist-induced Ca2+ entry in non-excitable cells, and their roles in modulating overall Ca2+ signals
A. William Tank
Regulation of tyrosine hydroxylase gene expression in the nervous system
Hugh Xia
Investigating the role of environmental toxins such as arsenic on the protein phosphatase-1, a regulator of synaptic plasticity and cognition.
Tingting Yang
Structure and function of calcium-activated chloride channels
David Yule
Mechanisms Underlying Ca2+ Signaling Events in Exocrine Cells

Secondary Faculty

Doug Anderson
LncRNA control of heart development and disease; Discovery and function of micropeptides encoded by putative lncRNAs; Genome-editing by RNA-guided nucleases.
Bradford Berk
Signal transduction mechanisms in the vasculature
Paul Brookes
Mitochondria and free radicals in cardiac ischemia-reperfusion
Laura Calvi
Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow
David Dean
Delineating mechanisms that control DNA-protein complexes’ traffic through the cytoplasm, entry to the nucleus, and targeting to specific domains, and application of this to treat pulmonary diseases.
Ian Dickerson
Molecular mechanisms of neuropeptide signal transduction
Roman Eliseev
Role of mitochondria in regulation of apoptosis and differentiation in cancer cells and in normal stem cells
Fabeha Fazal
Understanding the role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis, especially in the settings of acute and chronic lung injury
Robert Gross
Molecular pharmacology of neuronal signal transduction and ion channel activity
Stephen Hammes
How steroids regulate reproduction and hormone-dependent cancers
J. Christopher Holt
Synaptic pharmaco-physiology of vestibular efferent-afferent interactions
Gail Johnson
Defining molecular mechanisms of neurodegeneration, and regulation of cell death and survival processes in the central nervous system.
Sergiy Nadtochiy
Human Structure and Function
George Porter
Mechanisms that control the development of the heart
Arshad Rahman
Determining how exogenous agents change lung microvasculature permeability, leading to pulmonary inflammation.
Eileen Redmond
Vascular Effects of Alcohol-role of Notch
Peter Shrager
Neuron-neuroglia interactions
Eric Small
Understanding how a cell can interpret biomechanical and humoral signals and activate a discrete transcriptional program during development or in response to injury.
Richard Waugh
Cell Adhesion, Mechanical and thermodynamic properties of biological membranes; cellular mechanics and function of cytoskeletal proteins
R. White
Role of mitochondria in hypoxic pulmonary vasoconstriction.
Andrew Wojtovich
Optogenetics to study the roles of Reactive Oxygen Species (ROS) in mitochondrial physiology and stress signaling.

Emeritus Faculty

Marion Anders
Metabolism and toxicity of halogen- and sulfur-containing chemicals and on the design and synthesis of mitochondrially targeted drugs
Martha Blair
Neural and neuroendocrine control of cardiovascular function
Patricia Hinkle
Molecular Mechanisms of Cell Regulation
Ingrid Sarelius
Vascular cell communication and signaling