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Primary Faculty

Jean Bidlack
Pharmacology of brain and lymphocytic opioid receptors
Joe Chakkalakal
Contribution of stem cells to the maturation, regeneration and lifelong maintenance of skeletal muscle in growth aging and cancer
Robert Dirksen
Molecular Mechanisms of Calcium Signaling in Striated Muscle
Robert Freeman
Molecular biology of programmed cell death
Angela Glading
Role of cell-cell contact in regulating cellular function in both the normal and disease state
Suzanne Haber
Basal ganglia and degenerative diseases
Denise Hocking
Mechanism by which extracellular matrix protein, fibronectin affects cell and issue functions critical for would repair.
Paul Kammermeier
G protein coupled receptor signaling and modulation of ion channels in neurons
Whasil Lee
Mechanotransduction of musculoskeletal cells and associated human disease; Physiology and pathophysiology of mechanosensitive ion channels
John Lueck
Determining the therapeutic promise of engineered tRNAs for treatment of nonsense associated diseases and investigating the pathomechanisms of skeletal muscle weakness and wasting in myotonic dystrophy
David MacLean
Mechanisms of neurotransmitter receptor function
Trevor Shuttleworth
The nature of the conductances responsible for agonist-induced Ca2+ entry in non-excitable cells, and their roles in modulating overall Ca2+ signals
A. William Tank
Regulation of tyrosine hydroxylase gene expression in the nervous system
Hugh Xia
Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health
Tingting Yang
Structure and function of ion channels. Impact of dysfunction or dysregulation of BESTROPHINS and TMEM16s on disease mechanisms.
David Yule
Mechanisms Underlying Ca2+ Signaling Events in Exocrine Cells
Renjia Zhong
Renjia Zhong, MBBS, M.D.

Secondary Faculty

Doug Anderson
LncRNA control of heart development and disease; Discovery and function of micropeptides encoded by putative lncRNAs; Genome-editing by RNA-guided nucleases.
Bradford Berk
Signaling transduction mechanisms in the vasulcar system
Paul Brookes
Cardioprotection against ischemia-reperfusion (IR) injury. Role of Mitochondria and metabolism in ischemic preconditioning and anesthetic preconditioning.
Laura Calvi
Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow
David Dean
Delineating mechanisms that control DNA-protein complexes’ traffic through the cytoplasm, entry to the nucleus, and targeting to specific domains, and application of this to treat pulmonary diseases.
Ian Dickerson
Molecular mechanisms of neuropeptide signal transduction
Roman Eliseev
Role of Mitochondria in regulation of cell fate in normal stem cells and cancer cells
Fabeha Fazal
Role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permaeability, and apoptosis icute and chronic lung injury
Robert Gross
Molecular pharmacology of neuronal signal transduction and ion channel activity
Stephen Hammes
Androgen Effects on Reproduction and Cancer
J. Christopher Holt
Synaptic pharmaco-physiology of vestibular efferent-afferent interactions
Gail Johnson
Molecular mechanisms of Neurodegeneration, pathogenic processes in Alzheimer's disease and CNS injury
Sergiy Nadtochiy
Human Structure and Function
George Porter
Mechanisms that control the development of the heart
Arshad Rahman
Endothelial cell biology and lung physiology as it relates to molecular analysis of signal transduction and gene regulation in the lung epithelium.
Eileen Redmond
Vascular Effects of Alcohol-role of Notch
Peter Shrager
Neuron-neuroglia interactions
Eric Small
Understanding how a cell can interpret biomechanical and humoral signals and activate a discrete transcriptional program during development or in response to injury.
Richard Waugh
Cell Adhesion, Mechanical and thermodynamic properties of biological membranes; cellular mechanics and function of cytoskeletal proteins
R. White
Role of mitochondria in hypoxic pulmonary vasoconstriction.
Andrew Wojtovich
Optogenetics to study the roles of Reactive Oxygen Species (ROS) in mitochondrial physiology and stress signaling.

Emeritus Faculty

Marion Anders
Metabolism and toxicity of halogen- and sulfur-containing chemicals and on the design and synthesis of mitochondrially targeted drugs
Martha Blair
Neural and neuroendocrine control of cardiovascular function
Patricia Hinkle
Molecular Mechanisms of Cell Regulation
Ingrid Sarelius
Vascular cell communication and signaling