News and Events

2015-2016 Colloquium Series

Click here to view the Department of Pharmacology and Physiology Colloquium Series.

Department News

Dirksen to Head Department of Pharmacology & Physiology

undefined Robert T. Dirksen, Ph.D. will serve as chair of the Department of Pharmacology and Physiology at UR's School of Medicine and Dentistry (SMD) effective July 1, 2015. Bob, who has conducted research and taught medical and graduate students at the University since 1998, is known for his superb track record of federal funding, his collaborative nature, and his ability to inspire and engage trainees and colleagues alike.

Haber awarded $10 million Center Grant

undefined Suzanne N. Haber, Ph.D., Professor in the Department of Pharmacology and Physiology, was awarded a new Center Grant to study OCD at the University of Rochester School of Medicine and Dentistry. The goal of the $10 million grant is to improve understanding of the brain networks that play a central role in obsessive-compulsive disorder (OCD). Read full story here.

Featured August 26, 2015: New patent issued for Professor Hocking

Hocking The patent titled “Chimeric Fibronectin Matrix Mimetics and Uses Thereof” (US 9,072,706) has recently been assigned to the University of Rochester with inventors Denise C. Hocking, Ph.D. (Pharmacology and Physiology, BME, RCBU) and Daniel Roy, Ph.D. (BME PhD 2012 alumnus). The patent relates to a series of recombinant fibronectin peptide mimetics developed to promote wound repair. The technology falls under a new and exciting class of therapies known as wound biologics. The primary commercial application for this technology is to promote healing of hard-to-heal or chronic wounds, including diabetic, venous, and pressure ulcers, which impose a significant health care burden worldwide. Encouraging results from recent studies indicate that topical application of these fibronectin peptide mimetics to full-thickness excisional wounds in diabetic mice accelerates wound closure and promotes granulation tissue deposition, remodeling, and re-vascularization. Denise Hocking is an Associate Professor of Pharmacology and Physiology and of Biomedical Engineering. Daniel Roy is currently a post-doctoral fellow at the US Army Institute of Surgical Research in San Antonio, TX.

Congratulations to the following Graduate Students and Invited Student Speakers for winning poster awards at the 4th Annual Upstate New York Pharmacology Society (UNYPS) meeting G-Protein Coupled Receptor Signaling Systems in Health and Diseasewhich was held at the University of Rochester on May 19th, 2015. Graduate student winners were Hannah Stoveken, working in the lab of Dr. Gregory G. TallIsaac Fisher, working in the lab of Dr. Alan V. SmrckaAlex Hajduczok, working in the lab of Dr. Gregory G. Tall and Rafael Gil de Rubio, working in the lab of Dr. Alan V. SmrckaInvited student speaker winners were Walter Knight, Bharti Patel, graduate student in the lab of Dr. Gregory G. Tall and Jesi Lee Anne To, graduate student in the lab of Dr. Alan V. Smrcka

Congratulations to Hannah Stoveken, Graduate student in the lab of Gregory G. TallAssociate Professor of Pharmacology and Physiology, who took second place in the University's First Falling Walls Competition and $300. Honorable mention went to Yelena Lerman, a graduate student working with Minsoo Kim, Associate Professor of Microbiology and Immunology. Full article in Research Connections at the University of Rochester can be found here

Congratulations to Emma W. Grygotis who was the recipient of an Outstanding Student Presentation Award at the 2015 Therapeutic Ultrasound Winter School held in Les Houches, France on March 9-13, 2015 at the École de Physique des Houches. Emma is a second year graduate student in Pharmacology and Physiology working with Professor Denise C. Hocking (Pharmacology and Physiology, BME) and Professor Diane Dalecki (BME)

Congratulations to Pharmacology and Physiology graduate student Corey Hoffman, currently working in the lab of Dr. Laura M. Calvi. Corey was the winner of the “America’s Got Regulatory Science Talent" Award

Dr. David Yule invited to join Editorial Board of GastroenterologyYule

David I. Yule, Ph.D., Professor of Pharmacology and Physiology; of Medicine, Gastroenterology/Hepatology; and in the Center for Oral Biology has been invited to join the Editorial Board of Gastroenterology. Gastroenterology is the preeminent journal in the field of gastrointestinal disease. Gastroenterology is ranked 1st of 74 journals in the Gastroenterology and Hepatology category on the 2013 Journal Citation Reports, and has an Impact Factor of 13.926. As the official journal of the American Gastroenterological Association, Gastroenterology delivers up-to-date and authoritative coverage of both basic and clinical gastroenterology. Regular features include articles by leading authorities and reports on the latest treatments for diseases. Original research is organized by clinical and basic-translational content, as well as by alimentary tract, liver, pancreas, and biliary content.

UR Research in the News: Research Connections, October 3, 2014

Diane Dalecki, Professor of Biomedical Engineering and Director of the Rochester Center for Biomedical Ultrasound, and Denise C. Hocking, Associate Professor of Pharmacology & Physiology, have received a $2 million grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) for their project titled "Ultrasound standing wave fields for vascular engineering." The goal of this 4-year project is to advance a novel ultrasound technology to fabricate complex, functional microvascular networks within three-dimensional engineered constructs. Collaborators on this project are Maria Helguera, Associate Professor of Imaging Sciences at RIT; Ingrid H. Sarelius, Professor of Pharmacology and Physiology; and Angela J. Glading, Assistant Professor of Pharmacology and Physiology. New, versatile vascularization strategies are needed to produce small-scale 3D tissue models and are critical for the fabrication of large-scale engineered tissues. The noninvasive capacity of ultrasound also enables innovative capabilities for fabricating microvessel networks within hydrogels injected within tissues. The successful completion of this project will provide new tools for tissue engineering and for a variety of clinical reconstructive and vascular surgery applications. Click here for a video about these researchers' use of ultrasound for tissue engineering.

Featured in this weeks URMC Research Connections, March 14, 2014


Denise C. Hocking, PhD

Crossing Elmwood: Using ultrasound for tissue engineering

Tissue engineering has resulted in some remarkable achievements: skin substitutes, cartilage replacements, artificial bladders, urethral segments, blood vessels, bronchial tubes and corneal tissue substitutes.


Click here to read full article:

Paper of the Week, The Journal of Biological Chemistry, October 11, 2013

Kamil J. Alzayady

Kamil J. Alzayady, Ph.D.

David I. Yule, Ph.D.

David I. Yule, Ph.D.

A journal article by Kamil J. Alzayady, Larry E. Wagner II, Rahul Chandrasekhar, Alina Monteagudo, Ronald Godiska, Gregory G. Tall, Suresh K. Joseph, and David I. Yule was selected as a Paper of the Week by The Journal of Biological Chemistry.

Alzayady KJ, Wagner LE 2nd, Chandrasekhar R, Monteagudo AM, Godiska R, Tall GG, Joseph SK, and Yule DI. (2013) Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits. J Biol Chem. 288:29772-29784. (Paper of the Week)

Click here to view Kamil Alzayady's Author Profile.

2013 Convocation Award, September 12, 2013

Robert T. Dirksen, Ph.D. Dr. Robert T. Dirksen was selected as the 2013 recipient of the Excellence in Postdoctoral Mentoring Award. This award is presented to a postdoctoral mentor who shows dedication to postdoctoral trainees, as well as evidence of contributing significantly to their career development and professional advancement and was presented at the School of Medicine and Dentistry Convocation, September 12, 2013.

Faculty Focus Article

Alan V. Smrcka, Ph.D. Smrcka image

Dr. Alan V. Smrcka's recent article, "Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy," published in Cell was the subject of a faculty focus article published in Inside URMC

Cover Art for Tissue Engineering, Part B: Reviews, February, 2013

Denise C. Hocking, Ph.D. Daniel Roy, Ph.D. Tissue Engineering

An image by Dr. Denise C. Hocking and Dr. Daniel C. Roy was selected as cover art for Tissue Engineering, Part B: Reviews, Volume 19, Number 1, February 2013. This is a human mesenchymal stem cells adherent to a recombinant fibronectin mimetic substrate polymerize an endogenous fibronectin matrix (green) using α5β1 integrins (red).

Upstate New York Pharmacology Society, May 14, 2012

Paul J. Kammermeier, Ph.D.Paul J. Kammermeier, Ph.D., was elected a Councilor of the Upstate New York Pharmacology Society at its Inaugural Annual Meeting, May 14, 2012, at the University at Buffalo.

56th Annual Biophysical Society Meeting, February 24, 2012

Trevor J. Shuttleworth, Ph.D.Trevor J. Shuttleworth, Ph.D., was the Chair and Organizer of a satellite symposium on "Orai Channels -- New Insights, New Ideas," at the 56th Annual Biophysical Society Meeting, San Diego, California, February 24, 2012.

1st International Meeting on Ion Channel Signaling Mechanisms, October 31-November 4, 2011

Trevor J. Shuttleworth, Ph.D.Trevor J. Shuttleworth, Ph.D., was a Plenary Speaker at The First International Meeting on Ion Channel Signaling Mechanisms: from Basic Science to Clinical Application held in Marrakesh, Morocco, October 31-November 4, 2011.

Faculty Recognized at Convocation, October 5, 2011

Three Department of Pharmacology and Physiology faculty members were recognized by Dean Mark B. Taubman, M.D., at the URMC Opening Convocation on October 5, 2011, for appointment to five-year named profesorships:

Jean M. Bidlack, Ph.D. Jean M. Bidlack, Ph.D., Paul Stark Professorship in Pharmacology
Alan V. Smrcka, Ph.D. Alan V. Smrcka, Ph.D., Louis C. Lasagna Professorship in Experimental Therapeutics
A. William Tank, Ph.D. A. William Tank, Ph.D., Lewis Pratt Ross Professorship in Pharmacology and Physiology

NARSAD Distinguished Investigator Award

Suzanne N. Haber, Ph.D.Suzanne N. Haber, Ph.D., was a recipient of the NARSAD Distinguished Investigator Award, "Postnatal development of prefrontal white matter bundles." She also was invited to give a special lecture at the Society for Neuroscience Annual Meeting, entitled: "The Circuit of Reward and Value: Linking connectivity to Function and Disease CME."

University Dean's Award for Meritorious Service

Denise C. Hocking, Ph.D.Denise C. Hocking, Ph.D., was selected for The University Dean's Award for Meritorious Service in Ph.D. Defenses.

Department Press Releases

Suzanne N. Haber, Ph.D. Electrical Brain Stimulation May Strengthen Memory, Study Says
Robert T. Dirksen, Ph.D. Couch Potato Pill Might Stop Heat Stroke Too
Gregory G. Tall, Ph.D.

Scientists Fixate on Ric-8 to Understand Trafficking of Popular Drug Receptor Targets

Brookes Lab

Exploiting the body's own ability to fight a heart attack (February 25, 2010)

Probing New Ways to Reduce Damage from Heart Attack, Stroke (February 14, 2010)

Suzanne N. Haber, Ph.D.

Neuroscience Symposia Highlight Brain Research, Relevance for Patients (June 23, 2010)

$10.5 Million in funding creates center to study OCD (September 30, 2009)


Alan V. Smrcka, Ph.D.

Targeting Flight-or-Fight Hormone Response to Combat Heart Failure (June 24, 2010)

Study Unravels Detail of "Most Important" Cellular Signal (December 3, 2009)

Robert T. Dirksen, Ph.D.

Genetic Source of Muscular Dystrophy Neutralized (July 16, 2009)

Rare Genetic Syndrome May Hold Key to Cure for Heat Stroke (April 8, 2008)

Ingrid H. Sarelius and Denise C. Hocking

Decades-Old Question Answered: How Do Flexing Muscles Call for More Blood? (February 18, 2008)

Shey-Shing Sheu and Robert T. Dirksen

Researchers Unravel Key Mechanism of Cellular Demage in Aging and Disease (July 24, 2008)





Get In Touch

Department of Pharmacology and Physiology

University of Rochester Medical Center
601 Elmwood Avenue, Box 711
Rochester, NY 14642

Phone, (585) 275-1679
Fax, (585) 273-2652