URMC Research Network

Find People
Last Name
More Search Options

Inositol 1,4,5-Trisphosphate

"Inositol 1,4,5-Trisphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.

This graph shows the total number of publications written about "Inositol 1,4,5-Trisphosphate" by people in the URMC Research Network by year, and whether "Inositol 1,4,5-Trisphosphate" was a major or minor topic of these publication.