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Genes, BRCA1

"Genes, BRCA1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 17 at locus 17q21. Mutations of this gene are associated with the formation of familial breast and ovarian cancer. It encodes a large, nuclear protein that is a component of DNA repair pathways.

This graph shows the total number of publications written about "Genes, BRCA1" by people in the URMC Research Network by year, and whether "Genes, BRCA1" was a major or minor topic of these publication.