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Maximum Tolerated Dose

"Maximum Tolerated Dose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)

This graph shows the total number of publications written about "Maximum Tolerated Dose" by people in the URMC Research Network by year, and whether "Maximum Tolerated Dose" was a major or minor topic of these publication.