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Self Tolerance

"Self Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.

This graph shows the total number of publications written about "Self Tolerance" by people in the URMC Research Network by year, and whether "Self Tolerance" was a major or minor topic of these publication.