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Genes, Retinoblastoma

"Genes, Retinoblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

This graph shows the total number of publications written about "Genes, Retinoblastoma" by people in the URMC Research Network by year, and whether "Genes, Retinoblastoma" was a major or minor topic of these publication.