URMC Research Network

Find People
Last Name
More Search Options

Deoxyribonuclease I

"Deoxyribonuclease I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.

This graph shows the total number of publications written about "Deoxyribonuclease I" by people in the URMC Research Network by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publication.