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Axel Wismueller

InstitutionSchool of Medicine and Dentistry
DepartmentImaging Sciences
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 648
Rochester NY 14642
Other Positions
InstitutionSchool of Medicine and Dentistry
DepartmentBiomedical Engineering

InstitutionUniversity of Rochester, River Campus
DepartmentElectrical & Computer Engineering

 Awards And Honors
1996 - 1997Hanns Seidel Foundation Postgraduate Fellowship Award
2011     Upstate New York Translational Research Network (UNYTRN) Award  | Clinical and Translational Sciences Institute (CTSI)
2003 - 2005Ludwig Maximilians University Munich Research Grant
2010     Center for Emerging and Innovative Sciences (CEIS) Research Award  | Funded by NYSTAR
1999     Novartis Pharmaceutical Corporation Grant Award  | Segmentation of Lower Extremity Edema in MRI Data
1996     Wacker Chemical Corporation Research Grant Award
1998 - 1999Marconi Corporation Grant Award  | MRI Segmentation and Registration
2000 - 2001Max Planck Institute of Psychiatry Grant Award
2012     Harry W. Fischer Funds Award, University of Rochester Medical Center  | Imaging for Oncoplastic Resections of Breast Cancer
2012 - 2015Principal Investigator, National Institutes of Health (NIH)/NIDA R01 Award  | Brain Connectivity in HIV-Related Cognitive Impairment
1998     Max Planck Institute of Psychiatry Grant Award  | Explorative Analysis of Functional MRI Data of the Human Brain
1995     Hanns Seidel Foundation Scientific Conference Organization Grant Award
1995     Sun Microsystems Corporation Scientific Conference Organization Grant Award
1999     Institute of Phonetics Grant Award  | Ludwig Maximilians University Munich
2008     Charles and Janet Forbes Entrepreneurial Award for Biomedical Engineering Senior Design Project  | Department of Biomedical Engineering, University of Rochester
1982 - 1986State of Bavaria Scholarship Award for Outstanding Achievements
1997     Hanns Seidel Foundation, Senior Laureate Fellow
1985 - 1989Hanns Seidel Foundation Undergraduate Fellowship Award
2000 - 2003German Research Council (DFG) Graduate Research Program Award
Dr. Wismueller is Professor of Radiology and Biomedical Engineering at the University of Rochester Medical Center, where he directs the Computational Radiology Laboratory at the Department of Imaging Sciences. He received his M.D. (Dr. med.) degree from the Technical University of Munich, School of Medicine, in 1992, which included a scientific dissertation in neurology. In addition, he received a M.Sc. degree (Dipl.-Phys. Univ.) in Physics from the Ludwig Maximilians University Munich in 1996 for a scientific thesis on pattern recognition. From 1997 to 2005, he completed his radiology residency and a fellowship in Diagnostic Radiology at the Ludwig Maximilians University Medical Center in Munich, where he founded and established an interdisciplinary research team on digital image processing in radiology. In 2006, he received a Ph.D. degree (Dr. rer. nat.) from the Department of Electrical and Computer Engineering at the Technical University of Munich for a scientific dissertation on a novel pattern recognition algorithm invented by him (Exploratory Observation Machine - XOM), for which he holds several national and international patents.

Dr. Wismueller is author of more than 170 peer-reviewed scientific publications, holds U.S. and European medical licenses, multiple national and international patents, American and German Board Certifications in Diagnostic Radiology, a state doctorate (Habilitation) and an adjunct professorship (Privatdozent) with venia legendi for radiology at the Ludwig Maximilians University Munich.

Dr. Wismueller is the Principal Investigator of a recently granted active National Institutes of Health (NIH) R01 Award on "Brain connectivity in HIV-related cognitive impairment." Supported by NIDA and its AIDS research program and co-funded by the German Ministry of Research, this project focuses on developing a novel analysis approach for exploring information transfer in the human brain based on functional MRI neuro-imaging studies.

Based on his dual professional qualification in both science and medicine, Dr. Wismueller's main research interest is focused on innovative strategies for computational radiology. He is internationally known for his accomplishments in developing novel data exploration, pattern recognition, visualization, and machine learning methods for biomedical imaging. He introduced unsupervised learning techniques to image sequence processing with numerous clinical applications to functional MRI neuroimaging for human brain mapping, breast cancer workup, molecular imaging analysis, and the diagnosis of stroke.

Dr. Wismueller is an active member of multiple national and international professional societies in both medicine and engineering, such as RSNA and SPIE. He has organized multiple scientific conferences and special focus sessions at major international research conventions, has been active in numerous scientific program committees and as a scientific reviewer for highly renowned journals and conferences, and has served on numerous academic and administrative committees in both the U.S and Europe.

Dr. Wismueller has successfully supervised scientific theses of more than 30 Ph.D. and M.Sc. degree students from engineering, computer science, mathematics, biology, and academic medicine at both leading U.S. and European universities, and has advised three post-doctoral fellows. He has led multiple research studies on big data analysis in computational radiology, including a comprehensive research, publication, and funding track record. Besides several NIH-funded awards, he has served as Principal Investigator in a multi-center Translational Research Network Award of the Clinical and Translational Science Institute and in several NYSTAR-funded public-private research projects on biomedical imaging with leading industry partners.

 Selected Publications
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  1. Meyer-Baese A, Schlossbauer T, Lange O, Wismueller A. Small lesions evaluation based on unsupervised cluster analysis of signal-intensity time courses in dynamic breast MRI. Int J Biomed Imaging. 2009; 2009:326924.
    View in: PubMed
  2. Wismueller A, Behrends J, Hoole P, Leinsinger GL, Reiser MF, Westesson PL. Human vocal tract analysis by in vivo 3D MRI during phonation: a complete system for imaging, quantitative modeling, and speech synthesis. Med Image Comput Comput Assist Interv. 2008; 11(Pt 2):306-12.
    View in: PubMed
  3. Meyer-Baese A, Lange O, Wismueller A, Hurdal MK. Analysis of dynamic susceptibility contrast MRI time series based on unsupervised clustering methods. IEEE Trans Inf Technol Biomed. 2007 Sep; 11(5):563-73.
    View in: PubMed
  4. Meyer-Baese A, Wismueller A, Lange O. Comparison of two exploratory data analysis methods for fMRI: unsupervised clustering versus independent component analysis. IEEE Trans Inf Technol Biomed. 2004 Sep; 8(3):387-98.
    View in: PubMed


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