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Kevin Frick

TitleResearch Assistant Professor (Part-Time)
InstitutionSchool of Medicine and Dentistry
DepartmentMedicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 675
Rochester NY 14642
 
 Awards And Honors
1976 - 1979NSF Predoctoral Fellow
1975     High Honors in Biochemistry
1975     Distinction in General Scholarship
 
 Selected Publications
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  1. Frick KK, Asplin JR, Culbertson CD, Granja I, Krieger NS, Bushinsky DA. Persistence of 1,25D-induced hypercalciuria in alendronate-treated genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol. 2014 May; 306(9):F1081-7.
    View in: PubMed
  2. Ng AH, Frick KK, Krieger NS, Asplin JR, Cohen-McFarlane M, Culbertson CD, Kyker-Snowman K, Grynpas MD, Bushinsky DA. 1,25(OH)2D 3 Induces a Mineralization Defect and Loss of Bone Mineral Density in Genetic Hypercalciuric Stone-Forming Rats. Calcif Tissue Int. 2014 May; 94(5):531-43.
    View in: PubMed
  3. Frick KK, Asplin JR, Krieger NS, Culbertson CD, Asplin DM, Bushinsky DA. 1,25(OH)2D3-enhanced hypercalciuria in genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol. 2013 Oct; 305(8):F1132-8.
    View in: PubMed
  4. Frick KK, Asplin JR, Favus MJ, Culbertson C, Krieger NS, Bushinsky DA. Increased biological response to 1,25(OH)2D3 in genetic hypercalciuric stone-forming rats. Am J Physiol Renal Physiol. 2013 Mar; 304(6):F718-26.
    View in: PubMed
  5. Frick KK, Bushinsky DA. Effect of metabolic and respiratory acidosis on intracellular calcium in osteoblasts. Am J Physiol Renal Physiol. 2010 Aug; 299(2):F418-25.
    View in: PubMed
  6. Frick KK, Krieger NS, Nehrke K, Bushinsky DA. Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res. 2009 Feb; 24(2):305-13.
    View in: PubMed
  7. Krieger NS, Frick KK, LaPlante Strutz K, Michalenka A, Bushinsky DA. Regulation of COX-2 mediates acid-induced bone calcium efflux in vitro. J Bone Miner Res. 2007 Jun; 22(6):907-17.
    View in: PubMed
  8. Bushinsky DA, Frick KK, Nehrke K. Genetic hypercalciuric stone-forming rats. Curr Opin Nephrol Hypertens. 2006 Jul; 15(4):403-18.
    View in: PubMed
  9. Frick KK, LaPlante K, Bushinsky DA. RANK ligand and TNF-alpha mediate acid-induced bone calcium efflux in vitro. Am J Physiol Renal Physiol. 2005 Nov; 289(5):F1005-11.
    View in: PubMed
  10. Krieger NS, Frick KK, Bushinsky DA. Mechanism of acid-induced bone resorption. Curr Opin Nephrol Hypertens. 2004 Jul; 13(4):423-36.
    View in: PubMed
  11. Krieger NS, Bushinsky DA, Frick KK. Cellular mechanisms of bone resorption induced by metabolic acidosis. Semin Dial. 2003 Nov-Dec; 16(6):463-6.
    View in: PubMed
  12. Frick KK, Bushinsky DA. Metabolic acidosis stimulates RANKL RNA expression in bone through a cyclo-oxygenase-dependent mechanism. J Bone Miner Res. 2003 Jul; 18(7):1317-25.
    View in: PubMed
  13. Frick KK, Bushinsky DA. Molecular mechanisms of primary hypercalciuria. J Am Soc Nephrol. 2003 Apr; 14(4):1082-95.
    View in: PubMed
  14. Krieger NS, Frick KK, Bushinsky DA. Cortisol inhibits acid-induced bone resorption in vitro. J Am Soc Nephrol. 2002 Oct; 13(10):2534-9.
    View in: PubMed
  15. Bushinsky DA, Frick KK. The effects of acid on bone. Curr Opin Nephrol Hypertens. 2000 Jul; 9(4):369-79.
    View in: PubMed
  16. Frick KK, Bushinsky DA. In vitro metabolic and respiratory acidosis selectively inhibit osteoblastic matrix gene expression. Am J Physiol. 1999 Nov; 277(5 Pt 2):F750-5.
    View in: PubMed
  17. Frick KK, Bushinsky DA. Chronic metabolic acidosis reversibly inhibits extracellular matrix gene expression in mouse osteoblasts. Am J Physiol. 1998 Nov; 275(5 Pt 2):F840-7.
    View in: PubMed
  18. Frick KK, Jiang L, Bushinsky DA. Acute metabolic acidosis inhibits the induction of osteoblastic egr-1 and type 1 collagen. Am J Physiol. 1997 May; 272(5 Pt 1):C1450-6.
    View in: PubMed
  19. Furlanetto RW, Harwell SE, Frick KK. Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro. Mol Endocrinol. 1994 Apr; 8(4):510-7.
    View in: PubMed
  20. Frick KK, Scher CD. Platelet-derived growth factor-stimulated c-myc RNA accumulation in MG-63 human osteosarcoma cells is independent of both protein kinase A and protein kinase C. Mol Cell Biol. 1990 Jan; 10(1):184-92.
    View in: PubMed

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