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Inna Hughes

TitleSenior Instructor
InstitutionSchool of Medicine and Dentistry
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 631
Rochester NY 14642
 Awards And Honors
2007     Spencer T and Ann W. Olin Medical Scientist Fellow  | Washington University School of Medicine
1998     Minority Undergraduate Summer Internship Program  | Harvard School of Public Health
2004     Merlie Fine Sciences Travel Award  | Washington University School of Medicine
1999 - 2003Medical Scientist Training Program grant  | Washington University School of Medicine
2004     Graduate Student Presentation Award  | Stowers Institute, Mid-West Developmental Biology Meeting
2011     Alpha Omega Alpha Society  | University of Rochester Medical School
2004 - 2007Ruth L. Kirschstein National Research Service Award Individual Fellowship  | National Institutes of Health, National Institute on Deafness
2004     Viktor Hamburger Award  | Washington University School of Medicine
1995 - 1997Acceleration to Excellence Scholarship  | Simon's Rock College of Bard
2011     Upstate New York Regional Champions  | New York State Neurological Society, NeuroStakes
1999     Honors in Biology, Magna cum Laude  | Williams College
Inna Hughes, MD, PhD, is a Senior Instructor of Child Neurology and Epilepsy fellow at the University of Rochester. Her clinical interests are both in pediatric epilepsy and general child neurology. Dr. Hughes completed undergraduate studies at Williams College and graduated from Washington University in St Louis School of Medicine after completion of the combined MD, PhD program. She completed her child neurology residency training at the University of Rochester Medical Center in Rochester, NY. She is currently completing an epilepsy fellowship in addition to seeing general child neurology patients.

Dr. Hughes is board certified in Neurology with Special Qualification in Child Neurology. She is an active member in the American Academy of Neurology, American Epilepsy Society, and the Child Neurology Society. She has several research interests including the development and genetics of childhood onset epilepsy syndromes, dietary therapy in children and teens, and development of teaching and community programs to improve education and awareness for patients with epilepsy.

 Selected Publications
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  1. Hurle B, Marques-Bonet T, Antonacci F, Hughes I, Ryan JF. Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses. BMC Evol Biol. 2011; 11:23.
    View in: PubMed
  2. Wang H, Hughes I, Planer W, Parsadanian A, Grider JR, Vohra BP, Keller-Peck C, Heuckeroth RO. The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function. J Neurosci. 2010 Jan 27; 30(4):1523-38.
    View in: PubMed
  3. Hughes I, Binkley J, Hurle B, Green ED. Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members. BMC Evol Biol. 2008; 8:41.
    View in: PubMed
  4. Hughes I, Saito M, Schlesinger PH, Ornitz DM. Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12023-8.
    View in: PubMed
  5. Thalmann I, Hughes I, Tong BD, Ornitz DM, Thalmann R. Microscale analysis of proteins in inner ear tissues and fluids with emphasis on endolymphatic sac, otoconia, and organ of Corti. Electrophoresis. 2006 Apr; 27(8):1598-608.
    View in: PubMed
  6. Hughes I, Thalmann I, Thalmann R, Ornitz DM. Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development. Brain Res. 2006 May 26; 1091(1):58-74.
    View in: PubMed
  7. Hughes I, Blasiole B, Huss D, Warchol ME, Rath NP, Hurle B, Ignatova E, Dickman JD, Thalmann R, Levenson R, Ornitz DM. Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio. Dev Biol. 2004 Dec 15; 276(2):391-402.
    View in: PubMed
  8. Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM, Milbrandt J. GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 2004 Nov 18; 44(4):623-36.
    View in: PubMed


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