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Jonathan Flax

TitleResearch Assistant Professor
InstitutionSchool of Medicine and Dentistry
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 656
Rochester NY 14642
 Selected Publications
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  1. Flax JD, Soloway PD. Methylation on the mind. Nat Neurosci. 2011 Dec; 14(12):1494-6.
    View in: PubMed
  2. Ahmad I, Hunter RE, Flax JD, Snyder EY, Erickson RP. Neural stem cell implantation extends life in Niemann-Pick C1 mice. J Appl Genet. 2007; 48(3):269-72.
    View in: PubMed
  3. Park KI, Hack MA, Ourednik J, Yandava B, Flax JD, Stieg PE, Gullans S, Jensen FE, Sidman RL, Ourednik V, Snyder EY. Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells. Exp Neurol. 2006 May; 199(1):156-78.
    View in: PubMed
  4. Ourednik V, Ourednik J, Flax JD, Zawada WM, Hutt C, Yang C, Park KI, Kim SU, Sidman RL, Freed CR, Snyder EY. Segregation of human neural stem cells in the developing primate forebrain. Science. 2001 Sep 7; 293(5536):1820-4.
    View in: PubMed
  5. Rowitch DH, S-Jacques B, Lee SM, Flax JD, Snyder EY, McMahon AP. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci. 1999 Oct 15; 19(20):8954-65.
    View in: PubMed
  6. Park KI, Liu S, Flax JD, Nissim S, Stieg PE, Snyder EY. Transplantation of neural progenitor and stem cells: developmental insights may suggest new therapies for spinal cord and other CNS dysfunction. J Neurotrauma. 1999 Aug; 16(8):675-87.
    View in: PubMed
  7. Flax JD, Aurora S, Yang C, Simonin C, Wills AM, Billinghurst LL, Jendoubi M, Sidman RL, Wolfe JH, Kim SU, Snyder EY. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat Biotechnol. 1998 Nov; 16(11):1033-9.
    View in: PubMed
  8. Snyder EY, Yoon C, Flax JD, Macklis JD. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex. Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21):11663-8.
    View in: PubMed
  9. Snyder EY, Park KI, Flax JD, Liu S, Rosario CM, Yandava BD, Aurora S. Potential of neural "stem-like" cells for gene therapy and repair of the degenerating central nervous system. Adv Neurol. 1997; 72:121-32.
    View in: PubMed
  10. Lacorazza HD, Flax JD, Snyder EY, Jendoubi M. Expression of human beta-hexosaminidase alpha-subunit gene (the gene defect of Tay-Sachs disease) in mouse brains upon engraftment of transduced progenitor cells. Nat Med. 1996 Apr; 2(4):424-9.
    View in: PubMed


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