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Boxing In Cancer Genes, Boxing Out Disease

Boxing In Cancer Genes, Boxing Out Disease

Scientists believe they’ve figured out a way to suppress the growth of tumors by keeping DNA tightly packaged -- essentially burying some of the genes responsible for cancer. It’s a little like keeping the lid on the jack-in-the-box, said Willis Li, Ph.D., a professor of Medicine at UC San Diego, who did the work while in the Department of Biomedical Genetics at URMC.

Origins of Esophageal Cancer: Inflammation in the Gut

Origins of Esophageal Cancer: Inflammation in the Gut

Esophageal cancer is associated with GERD (gastrointestinal reflux disease), obesity, alcohol, and tobacco abuse. But the long march toward malignancy starts 10 to 20 years earlier when the cells, genes, and signaling pathways in the foregut begin a nefarious cooperative dance.

“Fingerprint” of Deadly Brain Cancer Uncovered

“Fingerprint” of Deadly Brain Cancer Uncovered

A team of researchers has successfully pinpointed the unique genetic characteristics of gliomas – a common and potentially deadly form of brain cancer.  The findings present scientists with a rich new set of targets for new therapies.