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Protein Key to Nerve Health Hitches a Ride on Brain’s Garbage Truck

Protein Key to Nerve Health Hitches a Ride on Brain’s Garbage Truck

A new study shows that the brain’s waste removal system serves as both trash collector and delivery service, providing neurons with a protein important to maintaining cognitive function while simultaneously cleaning brain tissue.  The research may help explain why different genetic varieties of the protein, called apolipoprotein E (apoE), can indicate risk for Alzheimer’s disease or promote longevity.

3/8/2017
It takes two to tango in HIV-associated brain damage

It takes two to tango in HIV-associated brain damage

HIV-associated brain damage occurs extensively, even in patients who are taking otherwise effective traditional anti-HIV therapy. This is a result of potent cooperation between two types of special immunological cells within the brain called monocytes and platelets. A recent paper published by University researchers in the Journal of Immunology demonstrates the presence of these platelet-monocyte ‘teams’ in HIV infected individuals and how these teams lead to increased neuronal damage.

 

6/3/2014
Bird Song Points to Potential New Huntington’s Treatment

Bird Song Points to Potential New Huntington’s Treatment

Mimicking the biology of canaries, researchers have successfully reprogrammed the brain’s native stem cells to create neurons capable of replacing the cells lost in Huntington’s disease.  The experiments – which were done in both mice and squirrel monkeys – could point to a new treatment strategy for the disease.

6/6/2013