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URMC / Research / Molecular Imaging Core / Instrumentation

 

Instrumentation

Storm 820 Phosphorimager

Storage phosphorimaging allows extremely sensitive detection and digitized quantization of radiolabeled (32P, 14C, 35S, 125I, and 3H) samples in gels, blots, and microtiter plates. The virtues of this technology include the elimination of the need for film, high sensitivity, linearity over five orders of magnitude and computerized analysis and storage of data. The Storm 820 Phosphorimager is located in 3-7424.

Contact: Hugh Higgins, (585) 275-3743

Typhoon 9410

The Typhoon 9410 is housed within the Center for RNA Biology. The instrument is a versatile system that handles gel sandwiches, agarose and polyacrylamide gels, membranes, microplates, and microarrays. Powerful excitation sources and innovative high-quality confocal optics allow for the sensitive detection of low-abundance targets. Red-, green-, and blue-excitation wavelengths and a wide choice of emission filters enable imaging of an extensive variety of fluorophores. Automated four-color fluorescence scanning allows multiplexing of multiple targets in the same sample ensuring accuracy of analysis, increasing throughput, and saving time. Storage phosphor technology delivers high-resolution imaging and accurate quantitation of 3H, 14C, 125I, 32P, 33P, 35S, and other sources of ionizing radiation. Highly sensitive optics enable direct chemiluminescent imaging without intermediate exposure to films or screens.

Contact: Scott Butler, Ph.D., (585) 275-7921, or Eric Phizicky, Ph.D., (585) 275-7268