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Upper GI Tract Cancer: 12 week home-based exercise study

Research Question:
Will walking and a progressive resistance program improve symptoms in patients with GI cancers with weight loss and cachexia (weakness of the body, and decreasing muscle mass)?

Basic Study Information

Purpose:
We would also like to find out if this exercise intervention improves physical performance, day-to-day function, quality of life, and how the exercise may affect markers of inflammation in the blood over time. Cancer cachexia is a complex condition that can result in weight loss, muscle weakness, and/or tiredness, and may affect your normal daily activities and quality of life. Cachexia is common in patients with upper gastrointestinal tract cancers (esophageal, stomach, bile duct or liver cancer, and pancreatic cancer). There is little information on how these symptoms may develop or change as cachexia progresses, or how exercise may help improve these symptoms. Currently more information is needed on how physical performance and quality of life is affected by cachexia. There are no drugs approved for cachexia so understanding cachexia and its effect on the body may guide the development of interventions to help other patients with cancer cachexia.

Location: University of Rochester Medical Center
Study Reference #: UGIM-16011

Lead Researcher (Principal Investigator)

Lead Researcher:  Richard Dunne

Study Contact Information

Study Coordinator: Nick Gerbino
Phone: (585) 273-2605
Email: Nicholas_Gerbino@URMC.Rochester.edu

Additional Study Details

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